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Research Results in Biomedicine

Volume 4, Issue №3, 2018
Genetics

EXPRESSION OF TOLL-LIKE RECEPTORS IN THE FEMALE REPRODUCTIVE TRACT AND ITS HORMONE REGULATION (REVIEW)

Background: Toll-like receptors (TLR) are the main receptors of the innate immune system, recognizing ligands of bacteria, viruses, fungi and protozoa ...

MOLECULAR-GENETIC ANALYSIS OF ASSOCIATIONS OF POLYMORPHOUS GENES COMBINATIONS OF THE XENOBIOTICS BIOTRANSFORMATION WITH THE ISOLATED VENTRICULAR SEPTAL DEFECT DEVELOPMENT IN THE KRASNODAR TERRITORY

Background: The study of the involvement of polymorphisms of candidate genes of the biotransformation system of xenobiotics in the formation of congenital malformations in children is one of the ...

MOLECULAR-GENETIC DETERMINANTS OF INFERTILITY IN GENITAL ENDOMETRYOSIS

Background: Genital endometriosis is an urgent problem of modern medicine. It is one of the hard-to-explain diseases and is the cause of reproductive health disorders, a decline in the ...

EVOLUTIONARY-GENETIC ANALYSIS OF THE ROLE OF REGULATORY REGIONS IN CORO2A GENE IN THE DEVELOPMENT OF HEREDITARY PREDISPOSITION TO PREECLAMPSIA IN RUSSIAN AND YAKUT ETHNIC GROUPS

Background: Preeclampsia (PE) is one of the most serious pregnancy complications and is the leading cause of maternal and perinatal morbidity and mortality, because there are currently no prognostic ...
Pharmacology, clinical pharmacology

THE PROBLEM OF EXPERIMENTAL MODEL CHOICE IN BIOMEDICAL RESEARCHES OF IMPLANTS (REVIEW)

Background: Biomedical researches and improvement of methods for medical materials manufacturing with certain properties and their pharmacological support caused the integration of achievements in materials science and medicine and ...

EVALUATION OF ANTIHYPOXIC ACTIVITY OF ETHYLMETHYLHYDROXIPYRIDINE SUKCINATE IN IN VITRO EXPERIMENTS

Background: The search for potential cardio- and cerebroprotective agents among the derivatives of oxypyridine is topical, since they are proven to contain the compounds with antihypoxic, antioxidant activity, and ...
Clinical Medicine

FACTORS AFFECTING THE DISSEMINATION AND PATOMORPHOSIS OF DISORDERS OF SEXUAL IDENTITY AND SEXUAL PREFERENCES (REVIEW)

Background: Disorders of sexual preferences and especially gender identity in recent years have attracted increasing attention due to the numerous media campaigns organized by LGBT people, which are becoming ...

PECULIARITIES OF THE OXIDATIVE STATUS IN ELDERLY PATIENTS WITH TYPE 2 DIABETES MELLITUS

Background: With age, diabetes mellitus becomes a frequent health problem in many people. However, to date, various clinical and pathophysiological aspects of the development and prevention of hypoglycemic conditions ...

ЭКСПРЕССИЯ БЕЛКОВ P16, P21 И P53 В БУККАЛЬНОМ ЭПИТЕЛИИ У ЛЮДЕЙ РАЗНОГО ВОЗРАСТА В НОРМЕ И ПРИ ХРОНИЧЕСКОМ ПАРОДОНТИТЕ

Background: Disturbances in the differentiation of cells and the processes of cellular renewal of the buccal epithelium, which occur when the functional activity of cells change, or with aging ...