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<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2658-6533</journal-id><journal-title-group><journal-title>Research Results in Biomedicine</journal-title></journal-title-group><issn pub-type="epub">2658-6533</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.18413/2658-6533-2019-5-4-0-6</article-id><article-id pub-id-type="publisher-id">1838</article-id><article-categories><subj-group subj-group-type="heading"><subject>Pharmacology</subject></subj-group></article-categories><title-group><article-title>A comparative analysis of physicians&amp;rsquo; basic knowledge with different work experience in the treatment of community-acquired pneumonia. Project &amp;laquo;КnoCAP&amp;raquo;, II phase (2017-2019)</article-title><trans-title-group xml:lang="en"><trans-title>A comparative analysis of physicians&amp;rsquo; basic knowledge with different work experience in the treatment of community-acquired pneumonia. Project &amp;laquo;КnoCAP&amp;raquo;, II phase (2017-2019)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Gavrilova</surname><given-names>Anna A.</given-names></name><name xml:lang="en"><surname>Gavrilova</surname><given-names>Anna A.</given-names></name></name-alternatives><email>g.annaa@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Bontsevich</surname><given-names>Roman A.</given-names></name><name xml:lang="en"><surname>Bontsevich</surname><given-names>Roman A.</given-names></name></name-alternatives><email>dr.bontsevich@gmail.com</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Prozorova</surname><given-names>Galina G.</given-names></name><name xml:lang="en"><surname>Prozorova</surname><given-names>Galina G.</given-names></name></name-alternatives><email>prozorovagg@gmail.com</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Kompaniets</surname><given-names>Olga G.</given-names></name><name xml:lang="en"><surname>Kompaniets</surname><given-names>Olga G.</given-names></name></name-alternatives><email>olga-kompaniets1@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Kirichenko</surname><given-names>Andrey A.</given-names></name><name xml:lang="en"><surname>Kirichenko</surname><given-names>Andrey A.</given-names></name></name-alternatives><email>andrey.apollonovich@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Krotkova</surname><given-names>Irina F.</given-names></name><name xml:lang="en"><surname>Krotkova</surname><given-names>Irina F.</given-names></name></name-alternatives><email>KROTIRA@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Myronenko</surname><given-names>Elena V.</given-names></name><name xml:lang="en"><surname>Myronenko</surname><given-names>Elena V.</given-names></name></name-alternatives><email>drolenamyronenko@gmail.com</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Luchinina</surname><given-names>Elena V.</given-names></name><name xml:lang="en"><surname>Luchinina</surname><given-names>Elena V.</given-names></name></name-alternatives><email>ELuchinina@gmail.com</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Shagieva</surname><given-names>Tatiana M.</given-names></name><name xml:lang="en"><surname>Shagieva</surname><given-names>Tatiana M.</given-names></name></name-alternatives><email>shagievatatiana@gmail.com</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Barysheva</surname><given-names>Valeriya O.</given-names></name><name xml:lang="en"><surname>Barysheva</surname><given-names>Valeriya O.</given-names></name></name-alternatives><email>valeriya.bar@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Ketova</surname><given-names>Galina G.</given-names></name><name xml:lang="en"><surname>Ketova</surname><given-names>Galina G.</given-names></name></name-alternatives><email>galina_ketova@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Martynenko</surname><given-names>Irina M.</given-names></name><name xml:lang="en"><surname>Martynenko</surname><given-names>Irina M.</given-names></name></name-alternatives><email>irina.martynenko11@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Shestakova</surname><given-names>Natalya V.</given-names></name><name xml:lang="en"><surname>Shestakova</surname><given-names>Natalya V.</given-names></name></name-alternatives><email>shestakovanv@list.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Galkina</surname><given-names>Irina P.</given-names></name><name xml:lang="en"><surname>Galkina</surname><given-names>Irina P.</given-names></name></name-alternatives><email>evseevaip@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Maximov</surname><given-names>Maxim L.</given-names></name><name xml:lang="en"><surname>Maximov</surname><given-names>Maxim L.</given-names></name></name-alternatives><email>maksim_maksimov@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Osipova</surname><given-names>Ol'ga А.</given-names></name><name xml:lang="en"><surname>Osipova</surname><given-names>Ol'ga А.</given-names></name></name-alternatives><email>OOsipova@gnicpm.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Milyutina</surname><given-names>Elena V.</given-names></name><name xml:lang="en"><surname>Milyutina</surname><given-names>Elena V.</given-names></name></name-alternatives><email>milutina.elena2011@yandex.ru</email></contrib></contrib-group><pub-date pub-type="epub"><year>2019</year></pub-date><volume>5</volume><issue>4</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/medicine/2019/4/Биомедицинские_исслеования_4_219-79-93.pdf" /><abstract xml:lang="ru"><p>Background: Community-acquired pneumonia (CAP) is an acute infectious inflammatory disease more often of bacterial etiology that occurs in outside hospital settings. This pathology is an important medical and social problem, which is associated with morbidity and mortality from pneumonia in the Russian Federation. Raising the level of awareness of doctors in pharmacotherapy of CAP will improve the level of care provided to the population. The aim of the study: To conduct a comparative analysis of basic knowledge among medical doctors with different backgrounds on the basic treatment of CAP. Materials and methods: The article represents the results of an anonymous prospective survey within the framework of the KNOCAP (the acronym of the project &amp;laquo;The assessment of physicians&amp;rsquo; knowledge of community-acquired pneumonia basics&amp;raquo;) multi-centered research project aimed at accessing the knowledge and preferences of doctors on the fundamental issues in diagnostics and treatment of community-acquired pneumonia. In 2017-2019, the survey involved 429 physicians from eleven Russian and Ukrainian centers. The method of anonymous questioning was used in this study, for which an original questionnaire was developed on the basis of current clinical recommendations. Results: For both young and more experienced doctors, the following questions caused the greatest difficulties: the choice of starting antimicrobial therapy in patients with and without risk factors, as well as the problem of indicating &amp;ldquo;typical&amp;rdquo; errors in the treatment of CAP. In general, the study showed a significant discrepancy in knowledge in the management of patients with CAP with the current clinical guidelines in 2010 and the draft new clinical guidelines in 2018-2019. Conclusion: In the course of the analysis, it was found that statistical significance in the difference in the management of patients with CAP among doctors with work experience of more than 5 years and less than 5 years is not always present. Also, a multicenter section of knowledge and preferences of specialists in many issues revealed their insufficient level for the correct management of patients with CAP.</p></abstract><trans-abstract xml:lang="en"><p>Background: Community-acquired pneumonia (CAP) is an acute infectious inflammatory disease more often of bacterial etiology that occurs in outside hospital settings. This pathology is an important medical and social problem, which is associated with morbidity and mortality from pneumonia in the Russian Federation. Raising the level of awareness of doctors in pharmacotherapy of CAP will improve the level of care provided to the population. The aim of the study: To conduct a comparative analysis of basic knowledge among medical doctors with different backgrounds on the basic treatment of CAP. Materials and methods: The article represents the results of an anonymous prospective survey within the framework of the KNOCAP (the acronym of the project &amp;laquo;The assessment of physicians&amp;rsquo; knowledge of community-acquired pneumonia basics&amp;raquo;) multi-centered research project aimed at accessing the knowledge and preferences of doctors on the fundamental issues in diagnostics and treatment of community-acquired pneumonia. In 2017-2019, the survey involved 429 physicians from eleven Russian and Ukrainian centers. The method of anonymous questioning was used in this study, for which an original questionnaire was developed on the basis of current clinical recommendations. Results: For both young and more experienced doctors, the following questions caused the greatest difficulties: the choice of starting antimicrobial therapy in patients with and without risk factors, as well as the problem of indicating &amp;ldquo;typical&amp;rdquo; errors in the treatment of CAP. In general, the study showed a significant discrepancy in knowledge in the management of patients with CAP with the current clinical guidelines in 2010 and the draft new clinical guidelines in 2018-2019. Conclusion: In the course of the analysis, it was found that statistical significance in the difference in the management of patients with CAP among doctors with work experience of more than 5 years and less than 5 years is not always present. Also, a multicenter section of knowledge and preferences of specialists in many issues revealed their insufficient level for the correct management of patients with CAP.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>community-acquired pneumonia</kwd><kwd>pharmacotherapy</kwd><kwd>clinical recommendations</kwd><kwd>pharmacoepidemiology</kwd><kwd>level of knowledge</kwd></kwd-group><kwd-group xml:lang="en"><kwd>community-acquired pneumonia</kwd><kwd>pharmacotherapy</kwd><kwd>clinical recommendations</kwd><kwd>pharmacoepidemiology</kwd><kwd>level of knowledge</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>[The incidence of the population of Russia in 2000-2009: Statistical materials]. Moscow: Minzdravsotsrazvitiya Rossii; 2010. Russian.</mixed-citation></ref><ref id="B2"><mixed-citation>Bilichenko TN, Bystritskaya EV, Chuchalin AG, et al. [Mortality of respiratory diseases in 2014-2015 and ways to reduce it].&amp;nbsp;Russian Pulmonology. 2016;26(4):389-397. Russian. DOI: https://doi.org/10.18093/0869-0189-2016-26-4-389-397</mixed-citation></ref><ref id="B3"><mixed-citation>Rachina SA, Sinopalnikov AI. [Clinical recommendations for community-acquired pneumonia in adults: what awaits us in 2019]. Practical pulmonology [Internet]. 2018 [cited 2019 Sept 15];3. Available from: https://cyberleninka.ru/article/n/klinicheskie-rekomendatsii-po-vnebolnichnoy-pnevmonii-u-vzroslyh-chto-nas-zhdet-v-2019-g. Russian.</mixed-citation></ref><ref id="B4"><mixed-citation>Chuchalin AG,&amp;nbsp;Stnopalnikov&amp;nbsp;AI,&amp;nbsp;Stratchounski LS, et al. [Community-acquired pneumonia in adults: guidelines on diagnosis, treatment and prophylaxis]. Klinicheskaya Mikrobiologiya i Antimikrobnaya Khimioterapiya. 2010;12(3):186-225. Russian.</mixed-citation></ref><ref id="B5"><mixed-citation>[Draft clinical guidelines of the Russian Respiratory Society for Community-Based Therapy]; 2018. [cited 2019 Nov 24]. Available from: http://spulmo.ru/download/ВП клинические рекомендац2019.pdf. Russian.</mixed-citation></ref><ref id="B6"><mixed-citation>Bontsevich RA, Schurovskaya KV, Pokrovskaya TG, et al. [Assessment of the knowledge of general practitioners in managing patients with community-acquired pneumonia MAKMAX-2015]. Klinicheskaya Mikrobiologiya i Antimikrobnaya Khimioterapiya. 2015;17(2):20. Russian.</mixed-citation></ref><ref id="B7"><mixed-citation>Bontsevich RA, Shchurovskaya KV, Gashynova K, et al. Assessment of senior medical students&amp;rsquo; knowledge in the reatment of patients with community-acquired pneumonia (KNOCAP project). The European Respiratory Journal. 2017;50(61):PA2767. DOI: 10.1183/1393003.congress-2017.PA2767</mixed-citation></ref><ref id="B8"><mixed-citation>Bontsevich RA, Filinichenko TS, Gavrilova AA, et al. Assessment of physicians&amp;rsquo; and senior medical students&amp;rsquo; knowledge in the treatment of patients with community-acquired pneumonia. Current results of the KNOCAP project. Research Results in Pharmacology. 2018;4(3):27-36.</mixed-citation></ref><ref id="B9"><mixed-citation>Bontsevich RA, Gavrilova AA, Prozorova GG, et al.&amp;nbsp;The assessment of physicians&amp;#39; knowledge of community-acquired pneumonia basics: KNOCAP study. The European Respiratory Journal. 2019;54(63):PA2922.</mixed-citation></ref><ref id="B10"><mixed-citation>Pertseva TA, Sanina NA. [The severity of systemic inflammatory reactions in patients with chronic obstructive pulmonary disease]. Pulmonology. 2013;1:38-41. Russian. DOI: https://doi.org/10.18093/0869-0189-2013-0-1-38-41</mixed-citation></ref><ref id="B11"><mixed-citation>Sinopalnikov AI. [Antibiotics and community-acquired lower respiratory tract infections. To whom? Which one?]. KMAH [Internet]. 2019 [cited 2019 Sept 15];1. Available from: https://cyberleninka.ru/article/n/antibiotiki-i-vnebolnichnye-infektsii-nizhnih-dyhatelnyh-putey-komu-kakoy. Russian.</mixed-citation></ref><ref id="B12"><mixed-citation>Rachina SA, Ivanchik NV, Kozlov RS. [Features of microbiological diagnosis in community-acquired pneumonia in adults]. Prakticheskaya pul&amp;#39;monologiya [Internet]. 2016 [cited 2019 Sept 23];4. Available from: https://cyberleninka.ru/article/n/osobennosti-mikrobiologicheskoy-diagnostiki-pri-vnebolnichnoy-pnevmonii-u-vzroslyh. Russian.</mixed-citation></ref><ref id="B13"><mixed-citation>Spichak TV. [Treatment of community-acquired pneumonia in the outpatient setting: learning to fail forward to success]. Medical Council. 2019;(11):172-178. Russian. DOI: https://doi.org/10.21518/2079-701X-2019-11-172-178</mixed-citation></ref><ref id="B14"><mixed-citation>Pertseva TO, Avramenko IV. [Particularities of laboratory indicators in relieving severe community-acquired pneumonia in patients]. Medical prospects [Internet]. 2017 [cited 2019 Sept 23];2. Available from: https://cyberleninka.ru/article/n/osoblivosti-laboratornih-pokaznikiv-perebigu-tyazhkoyi-negospitalnoyi-pnevmoniyi-u-patsientiv. Ukrainian.</mixed-citation></ref><ref id="B15"><mixed-citation>&amp;Ccedil;illi A, Sayıner A, &amp;Ccedil;elenk B, et al. Antibiotic treatment outcomes in&amp;nbsp;community-acquired&amp;nbsp;pneumonia. The Turkish Journal of Medical Sciences. 2018;48(4):730-736. DOI: 10.3906/sag-1709-144</mixed-citation></ref><ref id="B16"><mixed-citation>Cill&amp;oacute;niz C, Rodr&amp;iacute;guez-Hurtado D, Nicolini A, Journal of Thoracic Imaging. 2018;33(5):273-281. DOI: 10.1097/RTI.0000000000000343</mixed-citation></ref><ref id="B17"><mixed-citation>J, Jiang Q,&amp;nbsp;Isturiz R, et al. Effectiveness of 13-Valent Pneumococcal Conjugate Vaccine Against Hospitalization for Community-Acquired Pneumonia in Older US Adults: A Test-Negative Design. Clinical Infectious Diseases. 2018 Nov;67(10):1498-1506. DOI: 10.1093/cid/ciy312</mixed-citation></ref><ref id="B18"><mixed-citation>Lee MS, Oh JY, Kang CI, et al. Guideline for Antibiotic Use in Adults with Community-acquired Pneumonia. Infection and Chemotherapy. 2018;50(2):160-198. DOI: 10.3947/ic.2018.50.2.160</mixed-citation></ref><ref id="B19"><mixed-citation>Breitling LP, Saum KU, Schottker B, et al. Pneumonia in the noninstitutionalized older population. Dtsch Arztebl Int. 2016 Sep;113:607-614. DOI: 10.3238/arztebl.2016.0607</mixed-citation></ref><ref id="B20"><mixed-citation>Ewig S, Birkner N, Strauss R, et al. New perspectives on community-acquired pneumonia in 388 406 patients Results from a nationwide mandatory performance measurement programme in healthcare quality.&amp;nbsp;Thorax.&amp;nbsp;2009;64:1062-1069. DOI: http://dx.doi.org/10.1136/thx.2008.109785</mixed-citation></ref><ref id="B21"><mixed-citation>Sligl WI, Asadi L, Eurich DT, et al. Macrolides and mortality in critically ill patients with community-acquired pneumonia: a systematic review and meta-analysis. Crit Care Med. 2014;42:420-432. DOI: 10.1097/CCM.0b013e3182a66b9b</mixed-citation></ref></ref-list></back></article>