2658-6533Research Results in Biomedicine2658-653310.18413 / 2313-8955-2014-1-1-31-36228Archive categoriesPECULIARITY OF DIAGNOSIS AND EPIDEMIOLOGY OF GASTRIC AND DUODENAL ULCER IN HOSPITALIZED PATIENTSPECULIARITY OF DIAGNOSIS AND EPIDEMIOLOGY OF GASTRIC AND DUODENAL ULCER IN HOSPITALIZED PATIENTSVlasyukAleksandr Yu.VlasyukAleksandr Yu.doc-vlas@yandex.ruVlasyukVyacheslav Yu.VlasyukVyacheslav Yu.doc-vlas@yandex.ruKamyshnikovaLyudmila A.KamyshnikovaLyudmila A.kamyshnikova@bsu.edu.ru20141100

Peptic ulcer disease remains one of the most common diseases of the gastrointestinal tract. The article covers the clinical manifestations and diagnosis of gastric and duodenal ulcers in patients of different age groups treated in the gastroenterology department. The retrospective analysis of 205 case histories of patients treated in 2013 demonstrates the fact that the majority of patients were not tested on H. pylori- associated peptic ulcer disease and therefore there was a large possibility of a wrong choice of treatment. To solve the problem, there should be arranged the courses of advanced training in gastroenterology for all doctors involved. Besides, to avoid repeated hospitalizations and improve the effectiveness of treatment it is necessary to increase the patients’ compliance (the patients should be carefully instructed on compliance with recommendations given by doctors at discharge and taking medicines).

Peptic ulcer disease remains one of the most common diseases of the gastrointestinal tract. The article covers the clinical manifestations and diagnosis of gastric and duodenal ulcers in patients of different age groups treated in the gastroenterology department. The retrospective analysis of 205 case histories of patients treated in 2013 demonstrates the fact that the majority of patients were not tested on H. pylori- associated peptic ulcer disease and therefore there was a large possibility of a wrong choice of treatment. To solve the problem, there should be arranged the courses of advanced training in gastroenterology for all doctors involved. Besides, to avoid repeated hospitalizations and improve the effectiveness of treatment it is necessary to increase the patients’ compliance (the patients should be carefully instructed on compliance with recommendations given by doctors at discharge and taking medicines).

ulcerdiagnosistreatmenthospital epidemiologyulcerdiagnosistreatmenthospital epidemiologyСписок литературы1.     Vakhrouchev Y.M. Efremov L.I., Ephraim V.A. Yazvennaya bolezn': osobennosti techeniya na sovremennom etape i prognoz na blizhayshie gody / Terapevticheskiy arkhiv [Peptic Ulcer Disease: Characteristics of the Course at the Present Stage and the Forecast for the Next Few Years // Archives of Therapy]. 2008. № 8. pp.26-29.2.     Islamova E.A., Gromov M.S., Osadchuk M.A., Lipatov T.E. Vozrastnye aspekty kliniko-morfologicheskoy kharakteristiki i lecheniya yazvennoy bolezni dvenadtsatiperstnoy kishki //  Voenno-meditsinskiy zhurnal [Age Aspects of Clinical and Morphological Characteristics and Treatment of Duodenal Ulcer // Military Medical Journal]. 2008. № 11. pp.43-49.3.     Isakov V.A. Diagnostika i lechenie infektsii, vyzvannoy Helicobacter pylori: IV Maastrikhtskoe soglashenie / Novye rekomendatsii po diagnostike i lecheniyu infektsii H.pylori – Maastrikht IV (Florentsiya). Best Clinical Practice / Russkoe izdanie [Diagnostics and Treatment of Infections Caused by Helicobacter pylori: IV Maastricht Treaty / New guidelines for the Diagnosis and Treatment of H.pylori Infection – Maastricht IV (Florence ). Best Clinical Practice // Russian Edition]. 2012. Issue 2. pp.4 -23.4.     Lazebnik L.B., Sokolov G.N., Chernyaev A.Ya. Khronicheskie yazvy u lits pozhilogo vozrasta / Eksperimental'naya i klinicheskaya gastroenterologiya [Chronic Ulcers in the Elderly / // Experimental and Clinical Gastroenterology]. 2002. № 1. pp.3-7.5.     Lazebnik L.B., Drozdov V.N. Klinicheskie proyavleniya bolezni i pozhiloy vozrast // Zabolevaniya organov pishchevareniya u pozhilykh [Clinical Manifestations of the Disease and the Old Age // Diseases of the Digestive System in the Elderly]. M.: Anacharsis. 2003. pp. 25-34.6.     Maev I.V., Samsonov A.A. Yazvennaya bolezn' [Peptic Ulcer]. M. Miklos, 2009. 428 p.7.     Gorshenin T.L., Obolensky T.I., Sidorenko V.A., Smirnov A.A., Rusakievich K.I., Koloskov V.V. Osobennosti techeniya yazvennoy bolezni  dvenadtsatiperstnoy kishki u lyudey pozhilogo i starcheskogo vozrasta // Fundamental'nye issledovaniya [Peculiarities of Duodenal Ulcer Disease in the Elderly and Senile // Fundamental Research]. 2012. № 2. pp. 192-197.8.     Lazebnik L.B., Huseynzadeh M.G.o., Lee I.A., Efremov L.I. Epidemiologiya yazvennoy bolezni zheludka i dvenadtsatiperstnoy kishki (analiz statisticheskikh materialov) / Terapevticheskiy arkhiv [Epidemiology of Gastric Ulcer and Duodenal Ulcer (Statistical Analysis of Materials) // Therapeutic Archives. 2007. № 2. P. 12-16.9.     Admission Rates for Peptic Ulcer in the Trend Region, UK, 1972-2000, Changing Pattern, a Changing Disease? / Bardhan K.D., Williamson M., Royston C., Lyon C. // Dig Liver Dis. 2004. Vol.36. N9. pp. 577-588.10.                       Calvet Х. Accuracy of Monoclonal Stool Tests for Determining Cure of Helicobacter Pylori Infection after Treatment / Calvet Х, Lario S, Ramirez-Lazaro MJ // Helicobacter. 2010. 15. 201e5.11.                       Correa P. Natural History of Helicobacter pylori Infection / Correa P., Piazuelo M.B. // Dig Liver Dis. 2008. Vol.40. N7. pp. 490-496.12.                       Кonturek S.J. Нelicobacter pylori and its Involvement in Gastritis and Peptic Ulcer Formation / Кonturek S.J., Кonturek Р.С. // J. Рhysiol Рharmacol. 2006.  Vol. 57. № 3. pp. 29-50.13.                       Prevalence of Peptic Ulcer in Dyspeptic Patients and the Influence of Age, Sex, and Helicobacter Pylori Infection / H.C. Wu, B.G. Tuo, W.M. Wu et al. // Dig Dis Sci. 2008. Vol.53. N10.  pp. 2650-2656.14.                       Schwarzer А. Evaluation of а Novel Rapid One-step Monoclonal Chromatographic Immunoassay for Detection of Helicobacter pylori in Stool From Children / Schwarzer А, Lottspeich С, Russmann Н // Eur J Clin Microbiol Infect Dis. 2007. 26. 475е80.15.                       Shirin Н. Eradication of Helicobacter Pylori can be Accurately Confirmed 14 Days after Termination of Triple Therapy Using а High-dose Citric Acid-based 13С Urea Breath Test / Shirin Н, Levine А, Shevab О, еt al. // Digestion 2005;71: 208е12.16.                       Vogt, W. Gastroenterology in the Elderly // Praxis (Bern 1994). 2005. Vol. 94(48). pp. 1913-1918.