2658-6533Research Results in Biomedicine2658-653310.18413/2658-6533-2022-8-2-0-102750Medicine (miscellaneous)<strong>Peculiarities of postural disorders and connections with the blood compliment system in the case of falls syndrome in the elderly</strong><strong>Peculiarities of postural disorders and connections with the blood compliment system in the case of falls syndrome in the elderly</strong>GorkoTatyana S.GorkoTatyana S.mntk@mntk-tambov.ruAgarkovNikolai M.AgarkovNikolai M.vitalaxen@mail.ruLevInna V.LevInna V.michina.inna@mail.ruKorovinEvgeniy N.KorovinEvgeniy N.korovin@saums.vorstu.ruLeonGerman F.LeonGerman F.shukrullo2000@mail.ru20228200

Background:&nbsp;Natural and premature aging is accompanied by postural disorders, which are aggravated in patients with ophthalmic pathology and lead to the occurrence of the falls syndrome, but remain insufficiently studied in patients with angle-closure glaucoma with a change in the blood compliment system. The aim of the study:&nbsp;To study postural disorders and connections with the blood compliment system with angle-closure glaucoma. Materials and methods:&nbsp;The study was conducted in 62 elderly patients with falls syndrome and angle-closure glaucoma (main group) and 49 60-74-year-old patients with no falls and angle-closure glaucoma and other eye diseases. Postural disorders were studied using the Sensori Organization Test on a computer stabilometric complex in 6 functional tests (COND 1-6) and with an assessment of the somatosensory system, visual analyzer and the use of visual information in ensuring postural balance. The components of the blood compliment system were examined by enzyme immunoassay. The study of correlations was checked by the correlation method using the program &quot;Statistica 10.0&quot;. Results:&nbsp;Negative changes in postural balance in the elderly with falls syndrome and angle-closure glaucoma were detected in all 6 functional tests, but the most pronounced deterioration was noted in functional tests COND 2, COND 4 and COND 6. There was a decrease in the participation of the visual analyzer, somatosensory system and preference for using visual information in control of postural balance. Postural disturbances in patients with falls syndrome and angle-closure glaucoma are more associated with C3 C3a and C5a components of the blood compliment system and especially in functional tests COND 4, COND 6.&nbsp;Conclusion:&nbsp;Angle-closure glaucoma leads to impaired postural balance with fall syndrome associated with the blood compliment system.

Background:&nbsp;Natural and premature aging is accompanied by postural disorders, which are aggravated in patients with ophthalmic pathology and lead to the occurrence of the falls syndrome, but remain insufficiently studied in patients with angle-closure glaucoma with a change in the blood compliment system. The aim of the study:&nbsp;To study postural disorders and connections with the blood compliment system with angle-closure glaucoma. Materials and methods:&nbsp;The study was conducted in 62 elderly patients with falls syndrome and angle-closure glaucoma (main group) and 49 60-74-year-old patients with no falls and angle-closure glaucoma and other eye diseases. Postural disorders were studied using the Sensori Organization Test on a computer stabilometric complex in 6 functional tests (COND 1-6) and with an assessment of the somatosensory system, visual analyzer and the use of visual information in ensuring postural balance. The components of the blood compliment system were examined by enzyme immunoassay. The study of correlations was checked by the correlation method using the program &quot;Statistica 10.0&quot;. Results:&nbsp;Negative changes in postural balance in the elderly with falls syndrome and angle-closure glaucoma were detected in all 6 functional tests, but the most pronounced deterioration was noted in functional tests COND 2, COND 4 and COND 6. There was a decrease in the participation of the visual analyzer, somatosensory system and preference for using visual information in control of postural balance. Postural disturbances in patients with falls syndrome and angle-closure glaucoma are more associated with C3 C3a and C5a components of the blood compliment system and especially in functional tests COND 4, COND 6.&nbsp;Conclusion:&nbsp;Angle-closure glaucoma leads to impaired postural balance with fall syndrome associated with the blood compliment system.

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