<?xml version='1.0' encoding='utf-8'?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd">
<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2658-6533</journal-id><journal-title-group><journal-title>Research Results in Biomedicine</journal-title></journal-title-group><issn pub-type="epub">2658-6533</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.18413/2658-6533-2024-10-1-0-7</article-id><article-id pub-id-type="publisher-id">3338</article-id><article-categories><subj-group subj-group-type="heading"><subject>Medicine (miscellaneous)</subject></subj-group></article-categories><title-group><article-title>&lt;strong&gt;Features of geriatric status in patients with arterial hypertension and coronary heart disease (review)&lt;/strong&gt;</article-title><trans-title-group xml:lang="en"><trans-title>&lt;strong&gt;Features of geriatric status in patients with arterial hypertension and coronary heart disease (review)&lt;/strong&gt;</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Agarkov</surname><given-names>Nikolai M.</given-names></name><name xml:lang="en"><surname>Agarkov</surname><given-names>Nikolai M.</given-names></name></name-alternatives><email>vitalaxen@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Kopylov</surname><given-names>Andrey E.</given-names></name><name xml:lang="en"><surname>Kopylov</surname><given-names>Andrey E.</given-names></name></name-alternatives><email>mntk@mntk-tambov.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Titov</surname><given-names>Anton A.</given-names></name><name xml:lang="en"><surname>Titov</surname><given-names>Anton A.</given-names></name></name-alternatives><email>anton-titov-2001@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Negrebetsky</surname><given-names>Victor A.</given-names></name><name xml:lang="en"><surname>Negrebetsky</surname><given-names>Victor A.</given-names></name></name-alternatives><email>va_ivanov@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Osmanov</surname><given-names>Ruslan E.</given-names></name><name xml:lang="en"><surname>Osmanov</surname><given-names>Ruslan E.</given-names></name></name-alternatives><email>mntk@mntk-tambov.ru</email></contrib></contrib-group><pub-date pub-type="epub"><year>2024</year></pub-date><volume>10</volume><issue>1</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/medicine/2024/1/Биомед_исслед-113-126.pdf" /><abstract xml:lang="ru"><p>Background: Among the geriatric syndromes associated with the pathology of the cardiovascular system, in particular arterial hypertension (AH) and coronary heart disease as one of the causes of their occurrence, researchers call the syndrome of falls, senile asthenia syndrome (SAS), depression and cognitive impairment. The listed reasons indicate the relevance of their study and the implementation of preventive measures to reduce the prevalence in conceptual terms. The aim of the study: To analyze the geriatric status in patients with arterial hypertension and coronary heart disease, which will allow creating a plan for preventive measures to reduce the prevalence of geriatric syndromes in patients with arterial hypertension and coronary heart disease. Materials and methods: The analysis of the literature data on the geriatric status of patients with arterial hypertension and coronary heart disease published over the last decade was carried out: PubMed, Elibrary, Scopus. Results: Analysis of literature sources has shown that in the age cohort of senile persons, the prevalence of falls syndrome occurs in almost every second person, while 15-30% is in the group of 60-74 years. It has been shown that in predicting non-fatal complications with existing hypertension in geriatric patients with SAS, the pulse rate, systolic pressure, and laboratory parameters should be taken into account. The prevalence of depressive symptoms in patients with hypertension and coronary heart disease with various geriatric syndromes in different populations of countries ranges from 0.5 to 73.0% and its frequency depends on the diagnostic method used by the researchers. Despite the heterogeneity of the available information, it is indicated that depression occurs on average in 26.8% of AH patients with geriatric syndromes. Cognitive impairments were observed in 60.0% of AH and coronary heart disease patients with geriatric syndromes, and they develop due to the fact that in patients over 65 years of age, previous drug treatment has been ineffective for many years.Conclusion: The collected data may make it possible to create a plan for preventive measures to reduce the prevalence of geriatric syndromes in patients with arterial hypertension and coronary heart disease. Further research in this area will improve the quality of life of this population, which accounts for a significant proportion of hospitalizations and outpatient visits</p></abstract><trans-abstract xml:lang="en"><p>Background: Among the geriatric syndromes associated with the pathology of the cardiovascular system, in particular arterial hypertension (AH) and coronary heart disease as one of the causes of their occurrence, researchers call the syndrome of falls, senile asthenia syndrome (SAS), depression and cognitive impairment. The listed reasons indicate the relevance of their study and the implementation of preventive measures to reduce the prevalence in conceptual terms. The aim of the study: To analyze the geriatric status in patients with arterial hypertension and coronary heart disease, which will allow creating a plan for preventive measures to reduce the prevalence of geriatric syndromes in patients with arterial hypertension and coronary heart disease. Materials and methods: The analysis of the literature data on the geriatric status of patients with arterial hypertension and coronary heart disease published over the last decade was carried out: PubMed, Elibrary, Scopus. Results: Analysis of literature sources has shown that in the age cohort of senile persons, the prevalence of falls syndrome occurs in almost every second person, while 15-30% is in the group of 60-74 years. It has been shown that in predicting non-fatal complications with existing hypertension in geriatric patients with SAS, the pulse rate, systolic pressure, and laboratory parameters should be taken into account. The prevalence of depressive symptoms in patients with hypertension and coronary heart disease with various geriatric syndromes in different populations of countries ranges from 0.5 to 73.0% and its frequency depends on the diagnostic method used by the researchers. Despite the heterogeneity of the available information, it is indicated that depression occurs on average in 26.8% of AH patients with geriatric syndromes. Cognitive impairments were observed in 60.0% of AH and coronary heart disease patients with geriatric syndromes, and they develop due to the fact that in patients over 65 years of age, previous drug treatment has been ineffective for many years.Conclusion: The collected data may make it possible to create a plan for preventive measures to reduce the prevalence of geriatric syndromes in patients with arterial hypertension and coronary heart disease. Further research in this area will improve the quality of life of this population, which accounts for a significant proportion of hospitalizations and outpatient visits</p></trans-abstract><kwd-group xml:lang="ru"><kwd>geriatric status</kwd><kwd>geriatric syndromes</kwd><kwd>arterial hypertension</kwd><kwd>coronary heart disease</kwd><kwd>elderly</kwd></kwd-group><kwd-group xml:lang="en"><kwd>geriatric status</kwd><kwd>geriatric syndromes</kwd><kwd>arterial hypertension</kwd><kwd>coronary heart disease</kwd><kwd>elderly</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Gorelik SG, Ilnitskii AN, Zhuravleva YaV, et al. Basic clinical syndromes in geriatrics. Nauchnyye vedomosti Belgorodskogo gosudarstvennogo universiteta. Seriya: Meditsina. Farmatsiya. 2011;22(117)(16/1):100-104. Russian.</mixed-citation></ref><ref id="B2"><mixed-citation>Sharashkina NV, Runikhina NK, Litvina JUS, et al. Falls and geriatric syndromes in older adults with comorbidity. Clinical gerontology. 2020;26(1):9-14. Russian. DOI: https://doi.org/10.26347/1607-2499202001-02009-014</mixed-citation></ref><ref id="B3"><mixed-citation>Rausch C, Liang Y, Bultmann, et al. Social position and geriatric syndromes among Swedish older people: a population-based study. BMC Geriatrics. 2019;19(1):267. DOI: https://doi.org/10.1186/s12877-019-1295-8</mixed-citation></ref><ref id="B4"><mixed-citation>Naumov AV, Khovasova NO, Demenok DV, et al. Age-related musculoskeletal diseases as the leading risk factor for falls. Lechebnoye delo. 2019;1:62-73. Russian. DOI: https://doi.org/10.24411/2071-5315-2019-12091</mixed-citation></ref><ref id="B5"><mixed-citation>Gazibara T, Kurtagis I, Kisis-Tepavcevic D, et al. Falls, risk factors and fear of falling among persons older than 65 years of age. Psychogeriatrics. 2017;17(4):215-223. DOI: https://doi.org/10.1111/psyg.12217</mixed-citation></ref><ref id="B6"><mixed-citation>Edeleva AN, Sabgayda TP. Screening for senile asthenia syndrome among patients of primary care physicians and patients of nursing care department. Social aspects of population health. 2019;65(5):2. Russian. DOI: https://doi.org/10.21045/2071-5021-2019-65-5-2</mixed-citation></ref><ref id="B7"><mixed-citation>Alenskaya TL, Konevalova NY, Belov DF, etc. The clinical and social characteristic of the hypomobility syndrome at the patients with arterial hypertension in the concept of geriatric syndromes. Modern Problems of Science and Education. 2015;3:35. Russian</mixed-citation></ref><ref id="B8"><mixed-citation>Chudiak A, Uchmanowicz I, Mazur G. Relation between cognitive impairment and treatment adherence in elderly hypertensive patients. Clinical Interventions in Aging. 2018;13:1409-1418. DOI: https://doi.org/10.2147/CIA.S162701</mixed-citation></ref><ref id="B9"><mixed-citation>Zdrojewski T, Wizner B, Wiecek A, et al. Prevalence, awareness, and control of hypertension in elderly and very elderly in Poland: results of a cross-sectional representative survey. Journal of Hypertension. 2016;34(3):532-538. DOI: https://doi.org/10.1097/HJH.0000000000000823</mixed-citation></ref><ref id="B10"><mixed-citation>Tsyrlin VA, Kuzmenko NV, Pliss NG. Hypertension and cognitive disorders: causes and underlying mechanisms. Arterial Hypertension (Russian Federation). 2018;24(5):496-507. Russian. DOI: https://doi.org/10.18705/1607-419X-2018-24-5-496-507</mixed-citation></ref><ref id="B11"><mixed-citation>Seben R, Reichardt LA, Aarrden JJ, et al. The Course of Geriatric Syndromes in Acutely Hospitalized Older Adults: The Hospital-ADL Study. Journal of the American Medical Directors Association. 2019;20(2):152-158. DOI: https://doi.org/10.1016/j.jamda.2018.08.003</mixed-citation></ref><ref id="B12"><mixed-citation>Ostroumova OD, Cherniaeva MS, Morozov AP. Target blood pressure levels in patients with arterial hypertension and frailty. Systemic Hypertension. 2019;16(4):52-60. Russian. DOI: https://doi.org/10.26442/2075082X.2019.4.190577</mixed-citation></ref><ref id="B13"><mixed-citation>Shevchenko IN, Vlasenko VD. Features of modulation of cognitive functions of older patients with physiological and pathological aging. Mezhdunarodny studencheskiy nauchny vestnik. 2020;2:45. Russian.</mixed-citation></ref><ref id="B14"><mixed-citation>Jahan Y, Moriyama M, Rahman MM, et al. Disease perception and experiences among rural Bangladeshi hypertensive women: a qualitative approach. Health Promotion Perspectives. 2020;10(1):66-73. DOI: https://doi.org/10.15171/hpp.2020.11</mixed-citation></ref><ref id="B15"><mixed-citation>Yano Y, Bakris GI, Ohba Y, et al. Association of cognitive dysfunction with cardiovascular disease events in elderly hypertensive patients. Journal of Hypertension. 2014;32(2):423-431. DOI: https://doi.org/10.1097/HJH.0000000000000025</mixed-citation></ref><ref id="B16"><mixed-citation>Yurekli AA, Bilir N, Husain MJ. Projecting burden of hypertension and its management in Turkey, 2015-2030. PLoS ONE. 2019;14(9):e0221556. DOI: https://doi.org/10.1371/journal.pone.0221556</mixed-citation></ref><ref id="B17"><mixed-citation>Moskalenko MI, Ponomarenko IV, Polonikov AV, et al. The role of stress factors and genetic predisposition in the development of stroke in patients with essential hypertension. Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova. 2019;119(3‑2):11‑17. Russian. DOI: https://doi.org/10.17116/jnevro201911903211</mixed-citation></ref><ref id="B18"><mixed-citation>Almas A, Patel J, Ghori U, et al. Depression is linked to uncontrolled hypertension: a case-control study from Karachi, Pakistan. Journal of Mental Health. 2014;23(6):292-296. DOI: https://doi.org/10.3109/09638237.2014.924047</mixed-citation></ref><ref id="B19"><mixed-citation>Li H, Zheng D, Li Z, et al. Association of Depressive Symptoms With Incident Cardiovascular Diseases in Middle-Aged and Older Chinese Adults. JAMA network open. 2019;2(12)e1916591. DOI: https://doi.org/10.1001/jamanetworkopen.2019.16591</mixed-citation></ref><ref id="B20"><mixed-citation>Ena LM, Hristoforova GM, Akhaladze MG. Heriatric syndrome of depression in the patient of a pohilogo i starchekogo viku with hypertonic illness. Arterial hypertension. 2020;13(2):61-65. Russian. DOI: https://doi.org/10.22141/2224-1485.13.2-3.2020.205338</mixed-citation></ref><ref id="B21"><mixed-citation>Olenskaya TL, Konevalova NU, Gubarev YuD, et al. Prediction of the development of nonfatal outcomes in patients with hypertension of older age groups in the concept of geriatric syndromes. Modern Problems of Science and Education. 2015;1:1383. Russian.</mixed-citation></ref><ref id="B22"><mixed-citation>Sandstrom YK, Ljunggren G, Wandell P, et al. Psychiatric comorbidities in patients with hypertension &amp;ndash; a study of registered diagnoses 2009-2013 in the total population in Stockholm County, Sweden. Journal of Hypertension. 2016;34(3):414-420. https://doi.org/10.1097/HJH.0000000000000824</mixed-citation></ref><ref id="B23"><mixed-citation>Polishchuk YuI, Letnikova ZV. The syndrome of senile asthenia in gerontology and geriatrics from the point of view of gerontopsychiatry. Sotsialnaya i klinicheskaya psikhiatriya. 2018;28(4):71-74. Russian.</mixed-citation></ref><ref id="B24"><mixed-citation>Lavrinova EA, Bryliakova DN, Kukharchik GA. Influence of frailty syndrome on the course of non-ST-segment elevation acute coronary syndrome and outcomes in elderly and senile patients. Emergency medical care. 2020;21(2):48-54. Russian. DOI: https://doi.org/10.24884/2072-6716-2020-21-2-48-54</mixed-citation></ref><ref id="B25"><mixed-citation>Correa A, Rochlani Y, Khan MH, et al.&amp;nbsp;Pharmacological management of hypertension in the elderly and frail populations. Expert Review of Clinical Pharmacology. 2018;11(8):805-817. DOI: https://doi.org/10.1080/17512433.2018.1500896</mixed-citation></ref><ref id="B26"><mixed-citation>Tkacheva ON, Belenkov YuN, Karpov YuA, et al. Gerontology Issues in Cardiology Practice. Kardiologiia. 2019;59(12):54-63. Russian. DOI: https://doi.org/10.18087/cardio.2019.12.n876</mixed-citation></ref><ref id="B27"><mixed-citation>Runikhina NK, Tkacheva ON, Kotovskaya YuV, et al. Management of patients with senile asthenia in primary health care. Moscow: Izdatel&amp;#39;stvo RAMN; 2016. Russian.</mixed-citation></ref><ref id="B28"><mixed-citation>Ilnitski AN, Prashchayeu KI, Matejovska-Kubesova H, et al. Resilience in gerontology and geriatrics (review). Research Results in Biomedicine. 2019;5(4):102-116. Russian. DOI: https://doi.org/10.18413/2658-6533-2019-5-4-0-8</mixed-citation></ref><ref id="B29"><mixed-citation>Ostapenko VS, Runikhina NK, Tkacheva ON, et al. Screening tools for frailty in ambulatory care. Advances in Gerontology. 2016;29(2):306-312. Russian.</mixed-citation></ref><ref id="B30"><mixed-citation>Tuna F, Ustundag A, Can HB, et al. Rapid Geriatric Assessment, Physical Activity, and Sleep Quality in Adults Aged more than 65 Years: A Preliminary Study. Journal of Nutrition, Health and Aging. 2019;23(7):617-622. DOI: https://doi.org/10.1007/s12603-019-1212-z</mixed-citation></ref><ref id="B31"><mixed-citation>Ellis HL, Wan B, Yeung M, et al. Complementing chronic frailty assessment at hospital admission with an electronic frailty index (FI-Laboratory) comprising routine blood test results. CMAJ. 2020;192(1):E3-E8. DOI: https://doi.org/10.1503/cmaj.190952</mixed-citation></ref><ref id="B32"><mixed-citation>Tkacheva ON, Runikhina NK, Ostapenko VS, et al. Validation of the questionnaire for screening frailty. Advances in Gerontology. 2017;30(2):236-242. Russian.</mixed-citation></ref><ref id="B33"><mixed-citation>Chuvashova MS, Ivlichev AV, Kozlov AE. Optimization of medical and social care for the elderly by identifying &amp;quot;fragile&amp;quot; patients. Bulletin of Medical Internet Conferences. 2017;7(6):815. Russian.</mixed-citation></ref><ref id="B34"><mixed-citation>Aleksanyan YaN, Mileeva LV. The prevalence of obesity in elderly patients with senile astenia syndrome. Smolenskiy meditsinskiy al&amp;#39;manakh. 2020;1:194-195. Russian.</mixed-citation></ref><ref id="B35"><mixed-citation>Larina VN, Runikhina NK, Bart BY, et al. Risk of cardiovascular complications and geriatric syndromes among elderly women. Kardiologiia. 2017;57(3):58-64. Russian.</mixed-citation></ref><ref id="B36"><mixed-citation>Kocyigit SE, Soysal P, Bulut EA, et al. What is the relationship between frailty and orthostatic hypotension in older adults? Journal of Geriatric Cardiology. 2019;16(3):272-279. DOI: https://doi.org/10.11909/j.issn.1671-5411.2019.03.005</mixed-citation></ref><ref id="B37"><mixed-citation>Peters LL, Boter H, Burgerhof JGМ, et al. Construct validity of the Groningen Frailty Indicator established in a large sample of home-dwelling elderly persons: Evidence of stability across age and gender. Experimental Gerontology. 2015;69:129-141. DOI: https://doi.org/10.1016/j.exger.2015.05.006</mixed-citation></ref><ref id="B38"><mixed-citation>Daniels R, Rossum E, Beurskens A, et al. The predictive validity of three self-report screening instruments for identifying frail older people in the community.&amp;nbsp;BMC Public Health. 2012;12:69. DOI: https://doi.org/10.1186/1471-2458-12-69</mixed-citation></ref><ref id="B39"><mixed-citation>Gobbens RJ, Uchmanowicz I. Assessing Frailty with the Tilburg Frailty Indicator (TFI): A Review of Reliability and Validity. Clinical Interventions in Aging. 2021;16:863-875. DOI: https://doi.org/10.2147/CIA.S298191</mixed-citation></ref><ref id="B40"><mixed-citation>Olenskaya TL. The possibility of using the personality questionnaire of the Bechter Institute in patients with hypertension of older age groups in the concept of geriatric syndromes. Modern Problems of Science and Education. 2015;1:1310. Russian.</mixed-citation></ref></ref-list></back></article>