2658-6533Research Results in Biomedicine2658-653310.18413/2658-6533-2024-10-1-0-83339Medicine (miscellaneous)<strong>The role of negative childhood experiences and internal stigma in the formation of motivation for the treatment of patients with mental disorders</strong><strong>The role of negative childhood experiences and internal stigma in the formation of motivation for the treatment of patients with mental disorders</strong>GerasimchukEkaterina S.GerasimchukEkaterina S.katherine.gerasimchuk@mail.ruSorokinMikhail Yu.SorokinMikhail Yu.m.sorokin@list.ruLutovaNatalia B.LutovaNatalia B.lutova@mail.ruPortenierSergey N.PortenierSergey N.bekhterev_nii_2otd@mail.ruGorbunovaOlga V.GorbunovaOlga V.rybka200@mail.ru202410100

Background: Motivation for treatment is an important component of patients&#39; compliance to treatment of mental disorders, and its formation can be affected by different factors. The aim of the study: To analyze relationship between adverse childhood experiences, internal stigma and the intensity and structure of motivation to pharmaco-psychotherapy in patients with mental disorders. Materials and methods: The study involved 102 patients treated at the V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology, the Kashchenko Hospital, and the City Psychiatric Hospital No. 6. The study used the Adverse Childhood Experience (ACE) questionnaire, the Internalized Stigma of Mental Illness (ISMI) questionnaire, and the Treatment Motivation Assessment Questionnaire (TIMQ). Statistical analysis was performed using the SPSS 26.0 software package. Results: According to the results of multiple regression analysis, patients with higher education determined the improvement of patients&#39; motivation for treatment, increasing the probability of its high intensity by 5.92 times. The presence of each additional type of adverse experience in childhood also 1.4-fold increase the odds of intensive motivation of patients. Among individual variants of negative experience, emotional abuse was associated with a tenfold decrease in odds, while observing violence against a mother or stepmother in childhood was conversely associated with a fifteenfold increase in the odds of forming an intense motivation for treatment. Conclusion: Integrative role of adverse childhood experiences is important, but, unlike the internal stigma of mental disorder, it can be equally associated with both less adaptive motivational patterns during treatment. to both more and less adaptive motivational patterns in patients in the process of their treatment

Background: Motivation for treatment is an important component of patients&#39; compliance to treatment of mental disorders, and its formation can be affected by different factors. The aim of the study: To analyze relationship between adverse childhood experiences, internal stigma and the intensity and structure of motivation to pharmaco-psychotherapy in patients with mental disorders. Materials and methods: The study involved 102 patients treated at the V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology, the Kashchenko Hospital, and the City Psychiatric Hospital No. 6. The study used the Adverse Childhood Experience (ACE) questionnaire, the Internalized Stigma of Mental Illness (ISMI) questionnaire, and the Treatment Motivation Assessment Questionnaire (TIMQ). Statistical analysis was performed using the SPSS 26.0 software package. Results: According to the results of multiple regression analysis, patients with higher education determined the improvement of patients&#39; motivation for treatment, increasing the probability of its high intensity by 5.92 times. The presence of each additional type of adverse experience in childhood also 1.4-fold increase the odds of intensive motivation of patients. Among individual variants of negative experience, emotional abuse was associated with a tenfold decrease in odds, while observing violence against a mother or stepmother in childhood was conversely associated with a fifteenfold increase in the odds of forming an intense motivation for treatment. Conclusion: Integrative role of adverse childhood experiences is important, but, unlike the internal stigma of mental disorder, it can be equally associated with both less adaptive motivational patterns during treatment. to both more and less adaptive motivational patterns in patients in the process of their treatment

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