2658-6533Research Results in Biomedicine2658-653310.18413/2658-6533-2024-10-4-0-93597Medicine (miscellaneous)<strong>Quality of life of women with breast cancer after radical mastectomy and its socio-demographic determinants</strong><br /> &nbsp;<strong>Quality of life of women with breast cancer after radical mastectomy and its socio-demographic determinants</strong><br /> &nbsp;ZiminDmitry A.ZiminDmitry A.dmitriyzimin029@gmail.comPostoevVitaly A.PostoevVitaly A.ispha@nsmu.ruMenshikovaLarisa I.MenshikovaLarisa I.menshikova1807@gmail.comSonIrina M.SonIrina M.sonirinami@gmail.comSidorenkoKirill D.SidorenkoKirill D.kirillsidorenko451@gmail.com202410400

Background: Breast cancer is the most common malignant neoplasm among women. One of the main methods of treating breast cancer is surgery, including radical mastectomy, which, along with increased survival, can lead to a significant decrease in the quality of life. The aim of the study: To assess long-term quality of life and factors influencing it in patients of different ages after radical mastectomy using the Russian version of the BREAST-Q questionnaire. Materials and methods: A cross-sectional study was conducted with the participation of 150 patients of different ages who underwent radical mastectomy for breast cancer and are under dispensary supervision by an oncologist. Quality of life was assessed using the BREAST-Q questionnaire. To assess the impact of socio-demographic factors, the questionnaire included questions on age, social status, marital status, education, disability, self-rated health status on a scale from very poor to excellent, and self-rated physical pain on a scale from 0 to 5 points. Results: According to the results of the assessment of individual domains of quality of life using the BREAST-Q questionnaire, the following results were obtained: median breast satisfaction was 44 points, satisfaction with the psychosocial state was 52 points, satisfaction with the sexual state was 24 points, satisfaction with the physical condition was 40 points, satisfaction with the surgeon was 78 points, satisfaction with the medical staff was 80 points satisfaction with non-medical staff - 73 points. According to the results of multivariate analysis, significant predictors of breast satisfaction were self-assessment of physical health (&beta;corr=-5.83 (95%CI:-11.27; -0.39); satisfaction with psychosocial condition &ndash; age (&beta;corr=0.54 (95%CI:0.12; 0.95)), self-assessment of physical health &beta;corr=-8.28 (95%CI:-14.71; -1.84) and pain syndrome &beta;corr= -3.29 (95%CI:-6.42; -0.16), satisfaction with sexual state &ndash; age (&beta;corr=-0.57 (95% CI:-0.99; -0.15)), education &beta;corr=-8.88 (95%CI:-18.41; -0.64) for the average special and &beta;corr=-14.33 (95%CI:-26.65; -1.99) for the average)&nbsp; and marital status &beta;corr=-10.26 (95%CI:-17.90; -2.62), and satisfaction with physical condition &ndash; self-assessment of pain syndrome &beta;corr=5.83 (95%CI:3.57; 8.11). Conclusion: A low self-assessment of the quality of life of women of different ages was revealed with a sufficiently high variability of satisfaction by domains: self-assessment of health, pain syndrome and age, which were significant determinants of quality of life for the largest number of domains

Background: Breast cancer is the most common malignant neoplasm among women. One of the main methods of treating breast cancer is surgery, including radical mastectomy, which, along with increased survival, can lead to a significant decrease in the quality of life. The aim of the study: To assess long-term quality of life and factors influencing it in patients of different ages after radical mastectomy using the Russian version of the BREAST-Q questionnaire. Materials and methods: A cross-sectional study was conducted with the participation of 150 patients of different ages who underwent radical mastectomy for breast cancer and are under dispensary supervision by an oncologist. Quality of life was assessed using the BREAST-Q questionnaire. To assess the impact of socio-demographic factors, the questionnaire included questions on age, social status, marital status, education, disability, self-rated health status on a scale from very poor to excellent, and self-rated physical pain on a scale from 0 to 5 points. Results: According to the results of the assessment of individual domains of quality of life using the BREAST-Q questionnaire, the following results were obtained: median breast satisfaction was 44 points, satisfaction with the psychosocial state was 52 points, satisfaction with the sexual state was 24 points, satisfaction with the physical condition was 40 points, satisfaction with the surgeon was 78 points, satisfaction with the medical staff was 80 points satisfaction with non-medical staff - 73 points. According to the results of multivariate analysis, significant predictors of breast satisfaction were self-assessment of physical health (&beta;corr=-5.83 (95%CI:-11.27; -0.39); satisfaction with psychosocial condition &ndash; age (&beta;corr=0.54 (95%CI:0.12; 0.95)), self-assessment of physical health &beta;corr=-8.28 (95%CI:-14.71; -1.84) and pain syndrome &beta;corr= -3.29 (95%CI:-6.42; -0.16), satisfaction with sexual state &ndash; age (&beta;corr=-0.57 (95% CI:-0.99; -0.15)), education &beta;corr=-8.88 (95%CI:-18.41; -0.64) for the average special and &beta;corr=-14.33 (95%CI:-26.65; -1.99) for the average)&nbsp; and marital status &beta;corr=-10.26 (95%CI:-17.90; -2.62), and satisfaction with physical condition &ndash; self-assessment of pain syndrome &beta;corr=5.83 (95%CI:3.57; 8.11). Conclusion: A low self-assessment of the quality of life of women of different ages was revealed with a sufficiently high variability of satisfaction by domains: self-assessment of health, pain syndrome and age, which were significant determinants of quality of life for the largest number of domains

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