2658-6533Research Results in Biomedicine2658-653310.18413/2658-6533-2025-11-2-1-03775Medicine (miscellaneous)<strong>Effect of visual impairment and arterial hypertension on the prevalence of geriatric syndromes in elderly patients</strong><br /> &nbsp;<strong>Effect of visual impairment and arterial hypertension on the prevalence of geriatric syndromes in elderly patients</strong><br /> &nbsp;AryevAlexander L.AryevAlexander L.alex.l.ariev@gmail.comVoroninaNatalia V.VoroninaNatalia V.mdvoronina@yandex.ruParfenovYuri A.ParfenovYuri A.sav@expertsud.ruKlaritskayaIrina L.KlaritskayaIrina L.klira3@yandex.ruBelovVladislav N.BelovVladislav N.ovp.idpo@vrngmu.ruOdinaevShukhrat F.OdinaevShukhrat F.nnnn70@mail.ruSafuanovaGuzyal Sh.SafuanovaGuzyal Sh.kaf-kaf-tovpg@bashgmu.ruTolstovSergey N.TolstovSergey N.therapydpo@yandex.ru202511200

Background: Arterial hypertension and visual impairment due to various ophthalmopathologies are common age-related diseases, but their combined effect on the geriatric profile of patients has not been practically analyzed. The aim of the study: To analyse the effect of visual impairment and arterial hypertension on the prevalence of geriatric syndromes in elderly patients. Materials and methods: In accordance with the selected criteria, two clinical groups were formed: control group of 380 people with visual impairment due to cataracts, glaucoma or age-related macular degeneration;&nbsp; main group of 385 people with visual impairment due to the above-mentioned ophthalmological diseases and arterial hypertension. All patients underwent a comprehensive geriatric assessment to identify functional deficiencies. The association of functional deficits was performed on the basis of calculations of relative risk indicators according to a generally accepted formula with the determination of 95% confidence intervals. Results: The greatest differences in the prevalence of functional deficits between patients with visual impairment and patients with visual impairment and hypertension were found for falls syndrome (53.9&plusmn;2.9 and 68.0&plusmn;3.6 per 100 people, respectively, p&lt;0.01), sarcopenia (27.1&plusmn;1.6 and 42.1&plusmn;2.2 per 100 people, respectively, p&lt;0.001), depression (31.8&plusmn;1.9 and 46.0&plusmn;2.2 per 100 people, respectively, p&lt;0.001), sleep disorders (28.9&plusmn;2.0 and 40.5&plusmn;1.9 per 100 people, respectively, p&lt;0.01). There were no statistically significant differences in the compared groups in the prevalence of anxiety syndrome, hypomobility syndrome and malnutrition. Evaluation of the conjugation of functional deficits in elderly patients with visual impairment and arterial hypertension showed the strongest association with cognitive dysfunction (OR=2.012, 95% CI 1.975-2.248, p&lt;0.001). A significant effect of hypertension and visual impairment on the development of functional deficits was also found for depression (OR=1.835, 95% CI 1.642-2.104, p&lt;0.001), falls syndrome (OR=1.817, 95% CI 1.724-1.948, p&lt;0.001), sarcopenia (OR=1.956, 95% CI 1.804-2.237, p&lt;0.001). Conclusion: Visual impairment and hypertension increase the prevalence of geriatric syndromes in elderly patients and the risk of falls, cognitive impairment, sarcopenia, and depression by an average of 18-20%, which should be taken into account when implementing gerontoprophylactic measures

Background: Arterial hypertension and visual impairment due to various ophthalmopathologies are common age-related diseases, but their combined effect on the geriatric profile of patients has not been practically analyzed. The aim of the study: To analyse the effect of visual impairment and arterial hypertension on the prevalence of geriatric syndromes in elderly patients. Materials and methods: In accordance with the selected criteria, two clinical groups were formed: control group of 380 people with visual impairment due to cataracts, glaucoma or age-related macular degeneration;&nbsp; main group of 385 people with visual impairment due to the above-mentioned ophthalmological diseases and arterial hypertension. All patients underwent a comprehensive geriatric assessment to identify functional deficiencies. The association of functional deficits was performed on the basis of calculations of relative risk indicators according to a generally accepted formula with the determination of 95% confidence intervals. Results: The greatest differences in the prevalence of functional deficits between patients with visual impairment and patients with visual impairment and hypertension were found for falls syndrome (53.9&plusmn;2.9 and 68.0&plusmn;3.6 per 100 people, respectively, p&lt;0.01), sarcopenia (27.1&plusmn;1.6 and 42.1&plusmn;2.2 per 100 people, respectively, p&lt;0.001), depression (31.8&plusmn;1.9 and 46.0&plusmn;2.2 per 100 people, respectively, p&lt;0.001), sleep disorders (28.9&plusmn;2.0 and 40.5&plusmn;1.9 per 100 people, respectively, p&lt;0.01). There were no statistically significant differences in the compared groups in the prevalence of anxiety syndrome, hypomobility syndrome and malnutrition. Evaluation of the conjugation of functional deficits in elderly patients with visual impairment and arterial hypertension showed the strongest association with cognitive dysfunction (OR=2.012, 95% CI 1.975-2.248, p&lt;0.001). A significant effect of hypertension and visual impairment on the development of functional deficits was also found for depression (OR=1.835, 95% CI 1.642-2.104, p&lt;0.001), falls syndrome (OR=1.817, 95% CI 1.724-1.948, p&lt;0.001), sarcopenia (OR=1.956, 95% CI 1.804-2.237, p&lt;0.001). Conclusion: Visual impairment and hypertension increase the prevalence of geriatric syndromes in elderly patients and the risk of falls, cognitive impairment, sarcopenia, and depression by an average of 18-20%, which should be taken into account when implementing gerontoprophylactic measures

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