2658-6533Research Results in Biomedicine2658-653310.18413/2313-8955-2015-1-3-28-35470Archive categoriesORGANOMETRIC PARAMETERS OF RATS’ THYROID GLAND IN THE READAPTATION PERIOD AFTER 60-DAY ADMINISTRATION OF TARTRAZINE AND MEXIDOLORGANOMETRIC PARAMETERS OF RATS’ THYROID GLAND IN THE READAPTATION PERIOD AFTER 60-DAY ADMINISTRATION OF TARTRAZINE AND MEXIDOLMorozovVitaliy N.MorozovVitaliy N.vitaliyy-morozov@rambler.ruMorozovaElena N.MorozovaElena N.tiger2910@rambler.ru20151300

In the course of an organometric experiment with 245 white outbred mature male rats it was found that the use of 5% mexidol solution as a corrector (50 mg/kg body weight) results in smoothing changes in organometric parameters of the thyroid gland in mature rats in the period of readaptation caused by 60-day daily intragastric administration of tartrazine. The intensity and duration of the correcting effect of mexidol under experimental conditions were greater in the group using tartrazine with a dosage of 750 mg/kg and decreased at increasing its administered dose up to 1500 mg/kg body weight.

In the course of an organometric experiment with 245 white outbred mature male rats it was found that the use of 5% mexidol solution as a corrector (50 mg/kg body weight) results in smoothing changes in organometric parameters of the thyroid gland in mature rats in the period of readaptation caused by 60-day daily intragastric administration of tartrazine. The intensity and duration of the correcting effect of mexidol under experimental conditions were greater in the group using tartrazine with a dosage of 750 mg/kg and decreased at increasing its administered dose up to 1500 mg/kg body weight.

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