<?xml version='1.0' encoding='utf-8'?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd">
<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2658-6533</journal-id><journal-title-group><journal-title>Research Results in Biomedicine</journal-title></journal-title-group><issn pub-type="epub">2658-6533</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.18413/2313-8955-2015-1-3-118-130</article-id><article-id pub-id-type="publisher-id">482</article-id><article-categories><subj-group subj-group-type="heading"><subject>Archive categories</subject></subj-group></article-categories><title-group><article-title>COMPARATIVE ANALYSIS OF THE EXTRACTION ABILITY OF ETHYL ALCOHOL DIFFERENT CONCENTRATIONS TO ISOLATE A COMPLEX OF FLAVONOIDS FROM JUNIPERUS COMMUNIS L. FRUITS</article-title><trans-title-group xml:lang="en"><trans-title>COMPARATIVE ANALYSIS OF THE EXTRACTION ABILITY OF ETHYL ALCOHOL DIFFERENT CONCENTRATIONS TO ISOLATE A COMPLEX OF FLAVONOIDS FROM JUNIPERUS COMMUNIS L. FRUITS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Novikov</surname><given-names>Oleg O.</given-names></name><name xml:lang="en"><surname>Novikov</surname><given-names>Oleg O.</given-names></name></name-alternatives><email>ole9222@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Pisarev</surname><given-names>Dmitri I.</given-names></name><name xml:lang="en"><surname>Pisarev</surname><given-names>Dmitri I.</given-names></name></name-alternatives><email>juniper05@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Kornienko</surname><given-names>Irina V.</given-names></name><name xml:lang="en"><surname>Kornienko</surname><given-names>Irina V.</given-names></name></name-alternatives><email>indina@bsu.edu.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Malyutina</surname><given-names>Anastasia Yu.</given-names></name><name xml:lang="en"><surname>Malyutina</surname><given-names>Anastasia Yu.</given-names></name></name-alternatives><email>malyutina_a@bsu.edu.ru</email></contrib></contrib-group><pub-date pub-type="epub"><year>2015</year></pub-date><volume>1</volume><issue>3</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/medicine/2015/3/med16.pdf" /><abstract xml:lang="ru"><p>One of the plants, which have for a long time does not get the attention of researchers is the common juniper - Juniperus communis L. The results of the study of the pharmaceutical market of herbal remedies, indicate the absence of drugs of said plant. J. communis L. positioned as aromatic plants, but in the overall pharmacological effects of the plants involved polyphenol complex that is not fully understood. The literature also lacks information about the optimal solvent capable of removing the most complete range of polyphenolic compounds. The chemical composition of the fruit J. communis L. converted via Method-phase high performance liquid chromatography. The presence of 19 components of the flavonoid structure. The main components are glycosides of apigenin, and skutellyareina biflavonoidy. The comparative analysis of the extraction ability of alcohol to extract flavonoids J. communis L. It was found that ethyl alcohol 95% more fully extract apigenin glycosides. Ethyl alcohol concentration of 40%, better glycosides extracts skutellyareina. Biflavonoidy increasingly moving into dilute alcohol. Uniform output of all groups flavonoid extraction observed in 70% ethyl alcohol concentration. The highest total yield of flavonoids the extraction is observed when 95% ethyl alcohol. According to the research concluded that the most appropriate extractant for the fruits of flavonoids J. communis L. is 95% ethyl alcohol.</p></abstract><trans-abstract xml:lang="en"><p>One of the plants, which have for a long time does not get the attention of researchers is the common juniper - Juniperus communis L. The results of the study of the pharmaceutical market of herbal remedies, indicate the absence of drugs of said plant. J. communis L. positioned as aromatic plants, but in the overall pharmacological effects of the plants involved polyphenol complex that is not fully understood. The literature also lacks information about the optimal solvent capable of removing the most complete range of polyphenolic compounds. The chemical composition of the fruit J. communis L. converted via Method-phase high performance liquid chromatography. The presence of 19 components of the flavonoid structure. The main components are glycosides of apigenin, and skutellyareina biflavonoidy. The comparative analysis of the extraction ability of alcohol to extract flavonoids J. communis L. It was found that ethyl alcohol 95% more fully extract apigenin glycosides. Ethyl alcohol concentration of 40%, better glycosides extracts skutellyareina. Biflavonoidy increasingly moving into dilute alcohol. Uniform output of all groups flavonoid extraction observed in 70% ethyl alcohol concentration. The highest total yield of flavonoids the extraction is observed when 95% ethyl alcohol. According to the research concluded that the most appropriate extractant for the fruits of flavonoids J. communis L. is 95% ethyl alcohol.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>fructus Juniperi</kwd><kwd>flavonoids</kwd><kwd>extraction</kwd><kwd>converted-phase high performance liquid chromatography</kwd></kwd-group><kwd-group xml:lang="en"><kwd>fructus Juniperi</kwd><kwd>flavonoids</kwd><kwd>extraction</kwd><kwd>converted-phase high performance liquid chromatography</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Study of flavonoid composition shishkoyagody juniper dlinnohvoynogo / Pisarev D.I., Novikov O.O., Novikova M.J., Zhilyakova E.T.. Bulletin of Experimental Biology and Medicine. T. 150, № 12. 2010: P. 657-660.</mixed-citation></ref><ref id="B2"><mixed-citation>Kostyuchenko O.I. 6-oksiflavony in the plant world. Plant Resources. T.13, №2. 1977: P. 403-417.</mixed-citation></ref><ref id="B3"><mixed-citation>Klyshev L.K., Bandyukova V.A., Alyukina L.S. Flavonoids plants: distribution, physico-chemical properties, methods of research. Alma-Ata: Science, 1978. 220 p.</mixed-citation></ref><ref id="B4"><mixed-citation>Pisarev D.I. Overview of the current state of research in the field of taxonomy, chemistry and pharmacology of genus Juniperus L. Modern problems of phyto: Proceedings of the International scientific and practical conference (Belgorod, 28-31 May 2007). Belgorod: Publishing house BSU. 2007. P. 296-304.</mixed-citation></ref><ref id="B5"><mixed-citation>Sokolov S.I. Phytotherapy and phytopharmacology: a guide for doctors. M.: Med. Inf. Agency, 2000. 976 p.</mixed-citation></ref><ref id="B6"><mixed-citation>European Pharmacopoeia [Text]: 2 vol. &amp;ndash; 8th ed. European Directorate for Quality of Medicines and Health care. Strasbourg: Council of Europe. cop. 2014.</mixed-citation></ref></ref-list></back></article>