<?xml version='1.0' encoding='utf-8'?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "http://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd">
<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2658-6533</journal-id><journal-title-group><journal-title>Research Results in Biomedicine</journal-title></journal-title-group><issn pub-type="epub">2658-6533</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.18413/2313-8955-2016-2-3-18-22</article-id><article-id pub-id-type="publisher-id">768</article-id><article-categories><subj-group subj-group-type="heading"><subject>Medicine (miscellaneous)</subject></subj-group></article-categories><title-group><article-title>ATYPICAL COURSE OF BOTULISM IN THE ELDERLY</article-title><trans-title-group xml:lang="en"><trans-title>ATYPICAL COURSE OF BOTULISM IN THE ELDERLY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Gubarev</surname><given-names>Yuri D.</given-names></name><name xml:lang="en"><surname>Gubarev</surname><given-names>Yuri D.</given-names></name></name-alternatives><email>gubarev@bsu.edu.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Shcheblykina</surname><given-names>Olesya V.</given-names></name><name xml:lang="en"><surname>Shcheblykina</surname><given-names>Olesya V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Avdeeva</surname><given-names>Irina V.</given-names></name><name xml:lang="en"><surname>Avdeeva</surname><given-names>Irina V.</given-names></name></name-alternatives><email>Reizer95@rambler.ru</email></contrib></contrib-group><pub-date pub-type="epub"><year>2016</year></pub-date><volume>2</volume><issue>3</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/medicine/2016/3/18-22_D5laPwQ.pdf" /><abstract xml:lang="ru"><p>Despite a well-defined clinical picture, botulism is one of the diseases in which there is a significant number of diagnostic errors, that may be explained by its rarity and lack of knowledge of doctors of various specialties. The presence of symptoms common to many non-communicable diseases usually causes patients to refer to doctors of various specialties (neurologists, ophthalmologists, otolaryngologists, therapists, and others.), who very rarely make a correct primary diagnosis. That may be connected both with the features of the disease (including atypical) and the age of patients usually having an associated therapeutic and/or neurological history, to which many important diagnostic symptoms and syndromes are written off.</p></abstract><trans-abstract xml:lang="en"><p>Despite a well-defined clinical picture, botulism is one of the diseases in which there is a significant number of diagnostic errors, that may be explained by its rarity and lack of knowledge of doctors of various specialties. The presence of symptoms common to many non-communicable diseases usually causes patients to refer to doctors of various specialties (neurologists, ophthalmologists, otolaryngologists, therapists, and others.), who very rarely make a correct primary diagnosis. That may be connected both with the features of the disease (including atypical) and the age of patients usually having an associated therapeutic and/or neurological history, to which many important diagnostic symptoms and syndromes are written off.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>botulism</kwd><kwd>botulinum exotoxin</kwd><kwd>cholinergic structures</kwd><kwd>motor neurons</kwd><kwd>diplopia</kwd><kwd>dysphagia</kwd><kwd>advanced age</kwd><kwd>neutralization reaction</kwd></kwd-group><kwd-group xml:lang="en"><kwd>botulism</kwd><kwd>botulinum exotoxin</kwd><kwd>cholinergic structures</kwd><kwd>motor neurons</kwd><kwd>diplopia</kwd><kwd>dysphagia</kwd><kwd>advanced age</kwd><kwd>neutralization reaction</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Bondarev A.V.&amp;nbsp; The Problem of Diagnosing Botulism / A. V. Bondarev, A.V. Lobanov, V. I. Kuznetsov, S.A. Samarova, T. A. Perminov, D. A. Sretinskaya // Modern High Technologies. 2009. № 9. Pp. 81-82.</mixed-citation></ref><ref id="B2"><mixed-citation>Infectious Diseases: The National Guide / Ed. N.D. Yushchuk, Y.A. Vengerov. M.: GEOTAR Media. 2009. 1047 p.</mixed-citation></ref><ref id="B3"><mixed-citation>The Official Website of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare in Belgorod Region. URL: http://31.rospotrebnadzor.ru (date of access: June 21, 2016).</mixed-citation></ref><ref id="B4"><mixed-citation>The Official Website of FBUZ &amp;quot;Federal Center for Hygiene and Epidemiology&amp;quot; of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare. URL: http://fcgie.ru (date of access: June 21, 2016).</mixed-citation></ref><ref id="B5"><mixed-citation>Pokrovsky V.I., Pak S.G., Briko N.I. Infectious Diseases and Epidemiology: A Textbook for High Schools. M.: GEOTAR Media. 2004. 813 p.</mixed-citation></ref><ref id="B6"><mixed-citation>Sumin S. A. Emergencies: Textbook. 7-y ed., and ext. M.: OOO &amp;quot;Medical News Agency&amp;quot;. 2010. 960 p.</mixed-citation></ref><ref id="B7"><mixed-citation>Urazbakhtina Z.A. Emergency Treatment of Botulism / Z.A. Urazbakhtina, R.R. Tuktarova, V.B. Ivanov, S.H. Sarmanaev // Clinical Medicine. 2014. №1. Pp. 57-59.</mixed-citation></ref><ref id="B8"><mixed-citation>Human Physiology: a Textbook / Ed. V. M. Pokrovsky, G.F. Korotko. 2 nd ed., Revised. and ext. M .: Medicine. 2003. 656 p.</mixed-citation></ref><ref id="B9"><mixed-citation>Cherington M. Botulism: update and review. Semin. Neurol. 2004;24: 155-63.</mixed-citation></ref><ref id="B10"><mixed-citation>Horowitz B.Z. Botulinum toxin. Crit. Care Clin. 2005. 21: 825-39.</mixed-citation></ref><ref id="B11"><mixed-citation>Sobel J. Botulism. Clin. Infect. Dis. 2005. 41: 1167-73.</mixed-citation></ref><ref id="B12"><mixed-citation>Schmidt R.F., Thews G. Human physiology. Berlin; 1983. 1(6.3).</mixed-citation></ref><ref id="B13"><mixed-citation>Simpson L.L. Identification of the major steps in botulinum toxinaction. Annu. Rev. Pharmacol. Toxicol. 2004. 44: 167-93.</mixed-citation></ref><ref id="B14"><mixed-citation>Jaeger A. Botulism as warfare agent: features, management and treatment. Clin. Toxicol. 2002. 40: 244-6.</mixed-citation></ref><ref id="B15"><mixed-citation>&amp;nbsp;</mixed-citation></ref></ref-list></back></article>