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<article article-type="research-article" dtd-version="1.2" xml:lang="ru" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><front><journal-meta><journal-id journal-id-type="issn">2658-6533</journal-id><journal-title-group><journal-title>Научные результаты биомедицинских исследований</journal-title></journal-title-group><issn pub-type="epub">2658-6533</issn></journal-meta><article-meta><article-id pub-id-type="doi">10.18413 / 2313-8955-2015-1-1-54-63</article-id><article-id pub-id-type="publisher-id">350</article-id><article-categories><subj-group subj-group-type="heading"><subject>Архив</subject></subj-group></article-categories><title-group><article-title>КЛИНИЧЕСКИЙ СЛУЧАЙ ОСТРОГО ОТРЫВА ХОРДЫ ЗАДНЕЙ СТВОРКИ МИТРАЛЬНОГО КЛАПАНА У ПОЖИЛОЙ ПАЦИЕНТКИ С КОМОРБИДНОСТЬЮ</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL CASE OF ACUTE CHORD RUPTURE OF THE MITRAL VALVE POSTERIOR LEAFLET IN OLDER PATIENT WITH COMORBIDITIES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Кузнецов</surname><given-names>Игорь Владимирович</given-names></name><name xml:lang="en"><surname>Kuznetsov</surname><given-names>Igor V.</given-names></name></name-alternatives><email>kyznetsov_i_v@mail.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Лопин</surname><given-names>Дмитрий Александрович</given-names></name><name xml:lang="en"><surname>Lopin</surname><given-names>Dmytro O.</given-names></name></name-alternatives><email>doctorlopin@yandex.ru</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Крамаренко</surname><given-names>Ирина Анатольевна</given-names></name><name xml:lang="en"><surname>Kramarenko</surname><given-names>Irina A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Суманова</surname><given-names>Ирина Анатольевна</given-names></name><name xml:lang="en"><surname>Sumanova</surname><given-names>Irina A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Лопина</surname><given-names>Наталия Андреевна</given-names></name><name xml:lang="en"><surname>Lopina</surname><given-names>Natalia A.</given-names></name></name-alternatives><email>alamajor@yandex.ua</email></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="ru"><surname>Журавлёва</surname><given-names>Лариса Владимировна</given-names></name><name xml:lang="en"><surname>Zhuravlyova</surname><given-names>Larysa V.</given-names></name></name-alternatives><email>prof.zhuravlyova@gmail.com</email></contrib></contrib-group><pub-date pub-type="epub"><year>2015</year></pub-date><volume>1</volume><issue>1</issue><fpage>0</fpage><lpage>0</lpage><self-uri content-type="pdf" xlink:href="/media/medicine/2015/1/54-63.pdf" /><abstract xml:lang="ru"><p>В статье рассмотрена этиологическая роль различных факторов возникновения отрыва хорды митрального клапана таких как хроническая ревматическая болезнь сердца, бактериальный эндокардит, стеноз клапана аорты, артериальная гипертензия, ишемическая болезнь сердца, в том числе острый инфаркт миокарда, дегенеративная болезнь клапанов, заболевания соединительной ткани, травма грудной клетки, системная красная волчанка, врожденные пороки сердца, приведена существующая классификация данной нозологии, а также особенности манифестации и клинического течения. Также, описан клинический случай отрыва хорды задней створки митрального клапана у пациента с артериальной гипертензией, ишемической болезнью сердца и хронической обструктивной болезнью лёгких, отражающий все этапы диагностического поиска и трудности, возникшие при постановке диагноза, проанализированы основные концепции медикаментозного и оперативного лечения, особенности выбора лечебной тактики в зависимости от степени недостаточности митрального клапана.</p></abstract><trans-abstract xml:lang="en"><p>The article describes the etiologic role of various factors such as chronic rheumatic heart disease, bacterial endocarditis, aortic valve stenosis, hypertension, coronary heart disease, including acute myocardial infarction, degenerative disease of the valves, connective tissue diseases, chest trauma, systemic lupus erythematosus, congenital heart disease which leading to the mitral valve chords rupture, gives the current classification of the nosology and also features of manifestation and clinical course. The authors also described a clinical case of mitral valve posterior leaflet chord rupture in the patient with hypertension, ischemic heart disease and chronic obstructive pulmonary disease, which reflects all the stages of diagnostic search and the difficulties encountered in making the diagnosis. There were analyzed the basic concepts of medical and surgical treatment, features the choice of treatment strategy depending on the degree of mitral valve insufficiency.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>отрыв хорды</kwd><kwd>сердечная недостаточность</kwd><kwd>недостаточность митрального клапана</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chord rupture</kwd><kwd>congestive heart failure</kwd><kwd>mitral valve insufficiency</kwd></kwd-group></article-meta></front><back><ref-list><title>Список литературы</title><ref id="B1"><mixed-citation>Anderson Y. Fulminant mitral regurgitation due to ruptured chordae tendinae in acute rheumatic fever / Y. Anderson, N. Wilson, R. 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