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DOI: 10.18413/2658-6533-2026-12-2-0-7

Phytochemical and pharmacological properties of acetone extract fromCurcuma vitellina
 

Background:Curcuma vitellina has been recently described as a new species in the flora of Vietnam. To date, it is a rare species and its phytochemical and biological properties are limited. The aim of the study:The present study reports for the first time the chemical components and pharmacological properties of acetone extract of Curcuma vitellina, a native species from Vietnam. Materials and methods: The chemical components, antibacterial and antioxidant activitiesof the studied extract were identified using gas chromatography/mass spectrometry (GC/MS), agar disk-diffusion, and DPPH radical scavenging assays, respectively. Results: Forty-eight compounds were identified in the studied extract of which the major compounds were caryophyllene oxide (14.08%), (E)-labda-8(17),12-dien-15,16-dial (11.30%), longiverbenone (10.53%), 2-pentanone, 4-hydroxy-4-methyl- (9.98%), n-hexadecanoic acid (5.57%), and γ-bicyclohomofarnesal (5.13%). In addition, the studied extract was found to be effective against Gram-positive strains, including S. aureus ATCC 29213, S. aureus ATCC 25923, B. cereus and S. saprophyticus whereas while four Gram-negative strains were not sensitive to this extract. The C. vitellina extract also presented the DPPH scavenging capacity with IC50­ value of 614.55 µg/mL. Conclusion: The results from this report are to provide the potential application of the Curcuma vitellina extract in biomedicine and other related fields

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