FEATURES OF EPIDEMOLOGY OF STOMACH DISEASES, ASSOCIATED WITH HELICOBACTER PYLORI IN COMORBID DISEASES
The aim of the research was to study the frequency of visits of patients with exacerbations of chronic gastritis (CG), peptic ulcer (PU) of the stomach and duodenum, gastroesophageal reflux disease (GERD) in different age groups, depending on sex, Helicobacter pylori detectability, and concomitant pathology in outpatients. Materials and methods. A retrospective analysis of 2023 case histories from September 2016 to September 2017 of patients aged from 18 to 74 years, who underwent outpatient treatment in the polyclinic of Belgorod, was conducted. Results of the study and conclusion. In the study, patients with СG comprised the biggest group – 73.9%, patients with GERD comprised a smaller group – 16%, and patients with PU – 10.1%. An increase in the frequency of treatment of patients with exacerbations of CG is observed from the age of 50 and older, in females this pathology is 28.2% higher than in males. The number of women with GERD is 17.4% higher than the number of men. The debut of the pathology in males is registered from the age of 30-35, in women – at the age of 40-45 years. The peak incidence falls on the age of 55-65 years. PU is significantly more common in males. The highest frequency of morbidity in women is observed at the age of 36-40 years, in men – at the age of 30-35. Among the concomitant diseases the most frequently observed were: arterial hypertension, ischemic heart disease, dyscirculatory encephalopathy. It was revealed that in one and the same patient there were several nosological forms. As a result of the study, it was found that the diagnostics of H. pylori-associated diseases in a large number of patients was not carried out, as a result of this, the possibility of choosing an erroneous treatment tactic can be observed. To exclude this problem, it is necessary to conduct training and targeted advanced training of physicians in relation to gastroenterological diseases.
Kamyshnikova LA, Glavnova ES, Molchanova EG, et al. Features of epidemology of stomach diseases, associated with Helicobacter pylori in comorbid diseases. Research Result. Medicine and Pharmacy. 2017;3(4):3-10 (In Russian). DOI:10.18413/2313-8955-2017-3-4-3-10
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1. Afanasenkova, T.E., Nikitin, G.A., Ilyuschenkov, P.A. (2013), “The prevalence of exacerbations of stomach diseases associated with HELICOBACTER PYLORI, depending on age, gender and season of the year”, Doctor-graduate student, 57 (2, 3), 392-397. Russian.
2. Dvorkin, M.I. (2014), “Etiopatogenetic connection of Helicobacter pylori infection with atherosclerosis”, Vestnik KRSU, 14 (10), 101-104. Russian.
3. Zvenigorodskaya, L.A., Bondarenko, E.Yu., Morozov, I.A. (2007), “Peptic ulcer in the elderly: clinical features and significance of H. pylori”, Clinical gerontology, 1, 9-14. Russian.
4. Kamyshnikova, L.A., Vlasyuk, A.Yu., Vlasyuk, V.Yu. (2014), “Peculiarity of diagnosis and epidemiology of gastric and duodenal ulcer in hospitalized patients”, Research Result Medicine and pharmacy Series, 1 (1), 31-36. Russian.
5. Kamyshnikova, L.A., Efremova, O.A., Guseinli, E.G. (2016), “Modern review: Helicobacter pylori and risk of coronary heart disease”, Research Result.Medicine and pharmacy, 2(3), 3-10. Russian.
6. Lazebnik, L.B., Vasilyev, Yu.V., Shcherbakov, P.L. (2010), “HELICOBACTER PYLORI: prevalence, diagnosis, treatment”, Experimental and clinical gastroenterology, 2, 3-7. Russian.
7. Pakhomova, I.G., Zinovieva, E.N. (2017), “Gastroesophageal reflux disease in a polymorbid patient: features of therapy”, RMJ, 10, 760-764. Russian.
8. Stepanischeva, L.A., Sarsenbaeva, A.S., Fattakhova, N.V. (2013) “On the influence of comorbid diseases and risk factors on the development of a combined gastric ulcer and duodenal ulcer”, Journal of Experimental and Clinical Gastroenterology, 8, 34-40. Russian.
9. Cizginer, S.,Ordulu, Z., Kadayifci, A. (2014), “Approach to Helicobacter pylori infection in geriatric population”, World J Gastrointest Pharmacol Ther, 5 (3), 139-147.
10. Franceschi, F., Niccoli, G., Ferrante, G. Cag (2009), “A antigen of Helicobacter pylori and coronary instability: insight from a clinico-pathological study and a meta-analysis of 4241 cases”, Atherosclerosis, 202, 535-542.
11. Franceschi, M., Di Mario, F., Leandro, G., Maggi, S., Pilotto, A. (2009), “Acid-related disorders in the elderly”, Best Pract Res Clin Gastroenterol,
2, 839-848.
12. Hajimahmoodi, M., Shams-Ardakani, M., Saniee, P., Siavoshi, F., Mehrabani, M., Hosseinzadeh, H., Foroumadi, P., Safavi, M., Khanavi, M., Akbarzadeh, T. (2011), “In vitro antibacterial activity of some Iranian medicinal plant extracts against Helicobacter pylori”, Nat Prod Res, 25, 1059-1066.
13. Lv, Z.F., Wang, F.C., Zheng, H.L., Wang, B., Xie, Y., Zhou, X.J., Lv N.H. (2015), “Meta-analysis: is combination of tetracycline and amoxicillin suitable for Helicobacter pylori infection”, World J Gastroenterol, 21, 2522-2533.
14. Malfertheiner, P., Megraud, F., O’Morain, C.A., Atherton, J., Axon, A.Т.R., Bazzoli, F., Gensini, G.F., Gisbert, J.P., Graham, D.Y., Rokkas, T., El-Omar, E.M., Kuipers, E.J., European Helicobacter Study Group (EHSG) (2012), “Management of Helicobacter pylori infection – the Maastricht–IV/ Florence Consensus Report”, Gut, 61, 646-664.
15. Pentti Sipponen, Heidi-Ingrid Maaroos, Scand (2015), “Chronic gastritis”, J Gastroenterol, 50 (6), 657-667.
16. Rasmi, Y., Raeisi, S. (2009) “Possible role of Helicobacter pylori infection via microvascular dysfunction in cardiac syndrome X”, Cardiol. J., 16 (6), 585-587.
17. Shah, R. (2007), “Dyspepsia and Helicobacter pylori”, BMJ, 334, 41-43.
18. Safavi, M., Sabourian, R., Foroumadi, A. (2016), “Treatment of Helicobacter pylori infection: Current and future insights”, World J Clin Cases, 4 (1), 5-19.
19. Sumanen, M.P.T, Koskenvuo, M.J., Sillanmäki, L.H., Mattila, K.J. (2009), “Peptic ulcer and childhood adversities experienced by working-aged people”, World J Gastroenterol, 15(27), 3405-3410.
20. Taylor, D.N., Blaser M.J. (1991), “The epidemiology of Helicobacter pylori infection”, Epidemiol Rev, 13, 42-59.