Morphological changes in gum tissue during thiram intoxication followed by correction with resveratrol and sea buckthorn oil

Volume 10, Issue №1, 2024
Background: The widespread use of pesticides can lead to a violation of the ecological balance between the environment and the human body, provoking the development of oxidative ...

Targeting the Bap1 protein of Vibrio cholerae for screening potent inhibitors and predicting the mutant protein stability: in silico analyses

Volume 10, Issue №1, 2024
Background: Bap1 is reported to be a major protein in Vibrio cholerae which aids in biofilm formation. Hence, inhibition of the protein molecule can no longer support the ...

Curcumin Ameliorates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Endoplasmic Reticulum Stress in The Liver

Volume 9, Issue №4, 2023
Background: Nonalcoholic fatty liver disease (NAFLD) is a chronic pathological condition of the liver due to excess triglyceride accumulation in hepatocytes. The antioxidant properties of curcumin improve lipid ...

Seasonal periodontal microcirculation by combined stress in rats corrected with complex phytoadaptogen

Volume 9, Issue №4, 2023
Background: One of the negative inducers of the internal environment is inflammation; amongst external factors the most significant is polyetiological stress. One of the promising pharmacological methods of ...

Effect of pyrimidine derivative on cytokine levels in experimental generalized staphylococcal infection

Volume 9, Issue №3, 2023
Background: To date, bacterial infections caused by microorganisms characterized by antibiotic resistance are one of the leading causes of the protracted course of infectious and inflammatory diseases that occur with ...

Stress-protective activity of Astragalus physodes extract on the model of «social» stress

Volume 9, Issue №3, 2023
Background: In recent decades, in the conditions of human existence, special attention has been paid to the problem of stress and the body's response to the impact of stress ...

Effects of complex phytoadaptogens in matobolic syndrome

Volume 9, Issue №2, 2023
Background: The widespread prevalence of metabolic syndrome (MS) is becoming a serious problem for the population around the world, increasing the risk of developing type 2 diabetes and complications ...

Correction of mitochondrial dysfunction with cinnamic acids in experimental hypercytokinemia

Volume 8, Issue №3, 2022
Background: Mitochondrial dysfunction is an essential component of the hypercytokine neurotoxicity pathogenesis and is a promising pharmacotherapeutic target. The aim of the study: To evaluate the effect of cinnamic acids ...

Effect of sodium-glucose cotransporter type 2 inhibitors on the dynamics of functional and structural disorders in the simulation of post-contrast acute kidney injury

Volume 8, Issue №1, 2022
Background: Sodium-glucose cotransporter type 2 inhibitors have significantly changed nephroprotection strategies in various categories of patients over the past few years. However, there is no data on their ...
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