CHANGES IN THE LIPID COMPOSITION OF CELL MEMBRANES IN THE CONDITIONS OF PESTICIDES INTOXICATION AND METHODS OF THEIR PREVENTION
Today, the problem of high-toxic substances use in the agricultural sphere has a significant character. As a result, the number of intoxication cases has been growing both in warm-blood animals and humans. First of all, the most important toxic effect of pesticides is shown up in the damage of lipid metabolism. To predict the possibility of reducing the harmful pesticide effects, the potential of prophylactic use of Mexidol was studied for normalization of lipid metabolism in rats’ blood in the background of chronic pesticide intoxication. The study showed that Mexidol has a protective effect for the following lipid fractions: cholesterol and triacylglycerols.
Korolev VA, Korolev IV, Kharlanov NA, et al. Changes in the lipid composition of cell membranes in the conditions of pesticides intoxication and methods of their prevention. Research Result. Medicine and Pharmacy. 2017;3(4):11-16 (In Russian). DOI: 10.18413/2313-8955-2017-3-4-11-16
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