STUDIES ON THE DEVELOPMENT OF COMPOSITION AND TECHNOLOGY OF TABLETS FOR TREATMENT OF STOMATITIS
Among various inflammatory diseases of the oral cavity in children, stomatitis occupies a leading position in dentistry. The urgency of this problem is explained not only by the high prevalence of stomatitis in children's practice, but also by the chronicization of the pathological process, contagiousness and disorders of the immune system. According to the frequency of spread, infectious stomatitis of viral, bacterial or fungal etiology is in the first place. Great importance in the treatment of stomatitis in children is given to the local effects of drugs on the oral mucosa. The article substantiates the use of orodispersible tablets containing methylene blue and benzocaine, having a complex antiseptic and analgesic effect in the treatment of stomatitis of different etiologies. The article presents the results of experimental substantiation of the orodispersible tablets composition, the choice of the optimal technology for their production and quality indicators of tablet granulates and the finished product.
Pankrusheva TA, Maravina IN, Chekmareva MS. Studies on the development of composition and technology of tablets for treatment of stomatitis. Research Result. Medicine and Pharmacy. 2018;4(1):77-87 ( In Russian). DOI: 10.18413/2313-8955-2018-4-1-77-87
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