SIMULATION OF TOTAL BRAIN ISCHEMIA IN RATS
This paper deals with the study of the dependence of psycho neurological deficit in rats on the severity of brain damage, conducted on the four-vascular models of total cerebral ischemia. The obtained results demonstrate a tendency to deterioration of neuropsychiatric status of the animals with increasing severity of ischemic brain damage that allows suggesting the severity of ischemic brain damage and its correction by the degree of behavioral disorders.
Martynova OV, Gureev VV, Pokrovskiy MV, et al. Simulation of total brain ischemia in rats. Research Result. Medicine and Pharmacy Series. 2015;1(4):69-74 (In Russian). DOI: 10.18413 / 2313-8955-2015-1-4-69-74
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1. Gannushkina I.V. Cerebral blood flow in different types of circulatory brain hypoxia // Bulletin of the Russian Academy of Medical Sciences. 2000. No. 9. Pp. 22-27.
2. Miasishcheva O.V., Pokrovskii M.V., Gureev V.V., Antsiferov O.V., Martynov M.A. The experimental model of ischemic brain damage // Scientific papers of Belgorod State University. Medicine. Pharmacy. 2012. No. 11 (182) Edition 26/1. Pp. 123-127.
3. Shmonin A.A., Panov I.Iu., Simanenkova A.V., Prosvirnina M.S., Chekanov S.S., Melnikova E.V., Vlasov T.D. Endogenous neuroprotection in brain ischemia: erythropoietin, pre- and postconditioning // Annals of Clinical and Experimental Neurology. 2010. No. 3 (Vol. 4). Pp. 29-35.
4. Galagudza M.M., Blokhin I.O., Shmonin A.A., Mischenko K.A. Reduction of myocardial ischemia-reperfusion injury with pre- and postconditioning: molecular mechanisms and therapeutic targets// CardiovascHematolDisord Drug Targets. -2008. №8(1). P.47-65.
5. McGraw C.P., Pashayan A.G., Wendel O.T. Cerebral infarction in the Mongo- lian gerbil exacerbated by phenoxybenzamine treatment// Stroke. 1976; 7(5):485- 488.
6. Mitsuo Y., Calvert J.W., Kusaka G., Zhang J. H. One-Stage Anterior Approach for Four-Vessel Occlusion in Rat// Stroke. 2005. № 36. Р. 2212 2214.