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Research Results in Biomedicine

Volume 8, Issue №3, 2022 PDF
Genetics

Genetic variation of ERN1 and susceptibility to type 2 diabetes

Background: The endoribonuclease IRE1 (ERN1) is an important sensor for the endoplasmic reticulum unfolded protein response (UPR), and its activation happens as a result of the accumulation of ...

Genetic markers of severe preeclampsia

Background: In modern medicine, close attention is paid to the issues of reducing maternal morbidity and mortality, to the structure of which hypertensive disorders of gestation, especially ...
Pharmacology

In silico identification of the potential natural inhibitors of SARS-CoV-2 Guanine-N7 methyltransferase

Background: The outbreak of the COVID-19 pandemic caused by the SARS-CoV-2 has triggered intense scientific research into the possible therapeutic strategies that can combat the ravaging disease. One ...

Correction of mitochondrial dysfunction with cinnamic acids in experimental hypercytokinemia

Background: Mitochondrial dysfunction is an essential component of the hypercytokine neurotoxicity pathogenesis and is a promising pharmacotherapeutic target. The aim of the study: To evaluate the effect of ...
Medicine (miscellaneous)

Abnormal uterine bleeding: etiology and pathogenesis (descriptive review)

Background: Despite advances in medicine, uterine bleeding remains a well-known medical problem. Abnormal uterine bleeding has a negative impact on the physical, emotional, social, incl. material well-being of ...

Features of postural balance in working women aged 60-69

Background: The formation of the state policy for optimizing healthy and active aging, aimed at creating an incentive for older people to work longer, requires new knowledge ...

Effect of melanocortin neuropeptides on the level of apoptotic and neurotrophic factors under «social» stress

Background: Currently, scientific papers reflecting the results of studying the pathological influence of stress factors, including "social" stress, on various body systems are of particular interest. It ...