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Pharmacology

Pharmacological effect of indolicidin-like peptides on vasoactive substances content in experimental periodontitis

Volume 7, Issue №1, 2021
Background: The anti-inflammatory effect of indolicidin-like peptides, which have a wide range of antimicrobial effects, has been already reported in several studies. The inflammation of the periodontium is ...

Effects of first-line anti-TB drugs on the level of toxic plasma phospholipids
 

Volume 6, Issue №4, 2020
Background: The target of any toxic effect of anti-tuberculosis chemotherapy is primarily the cell. Changes in the structure and functions of cells affect the lipid composition of their ...

Morphofunctional changes in the retina when modeling the glaucoma process in rats
 

Volume 6, Issue №4, 2020
Background: Neuroprotective approaches are considered to be the most promising among existing modern directions in the development of antiglaucomatous drugs. The aim of the study: The detection of ...

Investigation of cerebroprotective properties of the drug «Mexidol» on the model of pneumococcal bacterial meningitis in experimental conditions

Volume 6, Issue №3, 2020
Background: Pneumococcal meningitis is a severe infectious disease, which is characterized by high mortality and frequent development of residual neurological damage. Effective cerebroprotection can improve the outcome of ...

Modern possibilities of using the release-active drug Tenoten for Children in the clinical practice of autonomic disorders in children
 

Volume 6, Issue №2, 2020
Background: Among the pathological conditions found in children and adolescents, vegetative disorders occupy one of the leading places. The development of autonomic dysfunction is due to an imbalance ...

Exhaled nitric oxide as a predictor of the effectiveness of basic therapy for bronchial asthma in children
 

Volume 6, Issue №2, 2020
Background: The article discusses the predictive ability of monitoring nitric oxide in exhaled air relative to the level of control and the likelihood of developing exacerbations of bronchial ...

A study of neuroprotective properties of the MGLUR4 receptor agonist – ZC64-0001 in comparison with Mexidol
 

Volume 6, Issue №2, 2020
Background: One of the most common neurodegenerative diseases is Parkinson's disease, which is based on the degeneration of dopaminergic neurons of the substantia nigra. The modern treatment for ...

Feasibility study of the eye drops composition with vitamins for the treatment of allergic conjunctivitis

Volume 5, Issue №4, 2019
Background: Today, quite a lot of people suffer from allergic conjunctivitis, despite the sufficient market of monocomponent medicines, there is a shortage of combined medicines based on modern substances ...

Determination of the antioxidant activity of the infusion of common sorrel herba in vitro

Volume 5, Issue №3, 2019
Background: Common sorrel (Rumex acetosa L.), a plant from the buckwheat family, is promising for introduction into medicine. Phytochemical studies of common sorrel herba showed that the raw material ...

The study of neurodynamic disturbances in rats with cranial injury

Volume 5, Issue №3, 2019
Background: Domestic and occupational injuries, including traumatic brain injury (TBI), are diseases that are a major public health problem in all industrialized countries and result in incapacitation, as well ...

The study of adaptogenic activity and toxicological safety of the Nigella damascena seed fatty oil extract

Volume 5, Issue №3, 2019
Background: Nigella damascena L. is a plant, extracts from which are characterized by a multicomponent composition of biologically active substances, which have an extensive spectrum of pharmacological properties. In ...

Practical aspects of the analysis of pharmaceutical substances by the indicator «bacterial endotoxins»

Volume 5, Issue №2, 2019
Background: Safety is one of the basic medicine requirements. «Bacterial endotoxins» is the most important safety indicator of parenteral drug ...
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