Pharmacology, clinical pharmacology
FEASIBILITY STUDIES OF THE DESIGN OF PHARMACEUTICAL DEVELOPMENT AND INDUSTRIAL INTRODUCTION OF PARENTERAL PREPARATIONS ON THE BASIS OF RECOMBINANT PROTEINS
Volume 2, Issue №3, 2016
In the conditions of introduction of the proper practice of production of medicinal facilities on pharmaceutical enterprises in Ukraine, it is necessary to develop effective measures of projects management for ...
FORMALIZATION OF CLINICAL INFORMATION FOR OPTIMIZATION OF DIAGNOSTIC AND TREATMENT PROCESS IN THERAPEUTIC PRACTICE
Volume 2, Issue №2, 2016
The creation of common and coherent information space for providing the diagnostic and treatment process expands opportunities of its improvement and optimization based on the computer technologies. The article proves ...
SOFTWARE IMPLEMENTATION OF THE SYSTEM OF COMPUTER ANALYSIS OF ECG WITH ADVANCED AUTOMATED SEARCH FOR CHARACTERISTIC AREAS
Volume 2, Issue №2, 2016
The article considers the system of computer analysis of ECG and the software implementation of this system. The system provides for automatic recognition of singular points of ECG and automatic ...
CLINICAL ANATOMY OF ATLANTO-OCCIPITAL VENOUS SINUS
Volume 2, Issue №1, 2016
A layer-by-layer dissection of the atlanto-occipital area of 25 adult cadavers who died from causes not related to pathology of the vascular system of the head is carried out. The ...
METHODOLOGY ANALYSIS MAPPING ELEMENTAL COMPOSITION OF MYOCARDIAL TISSUE WITH A SCANNING TRANSMISSION MICROSCOPY.
Volume 1, Issue №4, 2015
The article presents a method for the quantitative determination of the distribution of concentrations of chemical elements in biological sample. A method of mapping the macronutrient composition of biological samples ...
THE RELATIONSHIP BETWEEN PARAMETERS OF THE PEYER'S PATCHES OF THE SMALL INTESTINE IN INTACT RATS
Volume 1, Issue №4, 2015
This paper deals with the study of the relationship between parameters of the Peyer’s patches of the small intestine in intact rats of different age groups. The correlation analysis revealed ...
RESEARCH OF BEHAVIOURAL REACTIONS WHEN MODELLING THE TOTAL ISCHEMIA OF THE BRAIN
Volume 1, Issue №4, 2015
Dependence of psychoneurological deficiency at rats from severity of injury of a brain, on four-vascular model of a total ischemia of a brain is investigated. Results of research prove a ...
PHARMACOLOGICAL PRECONDITIONING WITH NICORANDIL AS A POSSIBILITY OF INCREASING THE STABILITY OF TISSUES OF THE RETINA TO ISCHEMIA IN AN EXPERIMENT
Volume 1, Issue №4, 2015
In laboratory rats, we formed an ischemic damage by providing mechanical pressure (110 mm Hg) to the anterior chamber for 30 minutes. The experiment has revealed the fact that nicorandil ...
MICROSCOPIC FEATURES OF BUCCAL EPITHELIUM OF THE INDIAN STUDENTS IN NRU "BSU"
Volume 1, Issue №4, 2015
Studied microscopic features of buccal epithelium Indian students in NRU "BSU". The appearance of the epithelium of the buccal mucosa single leukocytes, doble nuclei in the epithelial cells, cells with ...
MORPHOMETRIC STUDY OF HIPPOCAMPAL NEURONS IN CHRONIC IMMOBILIZATION STRESS
Volume 1, Issue №4, 2015
Hippocampus provides the implementation of the memory mechanisms, behavioral reactions, including avoidance of stress, aversive effects ect. The study was performed on the material of 20 male Wistar rats weighing ...
ENDOTHELIO-AND CARDIOPROTECTIVE EFFECTS OF HMG-Co-A REDUCTASE IN ENDOTOKSIN-INDUCING ENDOTELIAL DYSFUNCTION
Volume 1, Issue №4, 2015
The use of inhibitors of HMG-Co-A reductase inhibitor Simvastatin, Atorvastatin, Rosuvastatin and nanoparticulated Rosuvastatin on the background modeling of endotoxin-induced pathology through introduction of strain 603 Staphylococcusaureus leads to the ...
Correction of ADMA-Induced Preeclampsia with Use of Phosphodiesterase 5 and Selective Inhibitor of Arginase II ZB49-0010.
Volume 1, Issue №4, 2015
Simulation experimental ADMA-like preeclampsia was carried out by administering the rats L-NAME 14 to 20 days of pregnancy. In animals, there was an increase in blood pressure, proteinuria, impaired microcirculation ...
MICROSCOPIC FEATURES OF BUCCAL EPITHELIUM IN SMOKERS STUDENTS INDO-DRAVIDIAN RACE (BY E. HOOTON)
Volume 1, Issue №4, 2015
In smokers students Indo-Dravidian race the microscopic features of buccal epithelium were studied. Revealed in the epithelial cells of the mucous surface of the cheek of smoking students nucleuses with ...
THE ROLE OF MITOCHONDRIAL ATP-DEPENDENT POTASSIUM CHANNELS IN THE CARDIOPROTECTIVE EFFECT OF NICORANDIL ON THE MODEL OF CORONARY OCCLUSIVE MYOCARDIAL INFARCTION
Volume 1, Issue №4, 2015
The paper presents the results of a study of the antiischemic effectiveness of nicorandil (1,8 mg/kg) on the model of coronary occlusive myocardial infarction in rabbits. The coronary occlusion in ...
Perspective materials for drug delivery in the ophthalmic dosage form: a short review of polymers for electrospinning
Volume 4, Issue №4, 2018
Background: The traditional ophthalmological dosage forms have a low bioavailability, a rapid precorneal clearance and a low corneal permeability. The gelling system or system with a prolonged action (prolonged ...
Pharmacological correction of metabolic disturbances in experimental acute pancreatitis on the background of chronic alcohol intoxication
Volume 4, Issue №4, 2018
Background: Acute pancreatitis ranks third among all acute surgical diseases of the abdominal cavity and is one of the important unresolved problems in emergency surgery. The aim of the ...
Development of the composition and analysis of suppositories of antihemorrhoidal action
Volume 4, Issue №4, 2018
Background: The study is devoted to the development of composition and assessment of the quality of two-layered suppositories with an oil extract of rowanberries (<span ...
EVALUATION OF ANTIHYPOXIC ACTIVITY OF ETHYLMETHYLHYDROXIPYRIDINE SUKCINATE IN IN VITRO EXPERIMENTS
Volume 4, Issue №3, 2018
Background: The search for potential cardio- and cerebroprotective agents among the derivatives of oxypyridine is topical, since they are proven to contain the compounds with antihypoxic, antioxidant activity, ...
APPROACHES TO CORRECTION OF ISCHEMIC AND REPERFUSION KIDNEY INJURIES IN EXPERIMENT
Volume 4, Issue №3, 2018
Background: Acute kidney injury is an urgent health problem at the junction of specialties with a high level of disability and ...
THE PROBLEM OF EXPERIMENTAL MODEL CHOICE IN BIOMEDICAL RESEARCHES OF IMPLANTS (REVIEW)
Volume 4, Issue №3, 2018
Background: Biomedical researches and improvement of methods for medical materials manufacturing with certain properties and their pharmacological support caused the integration of achievements in materials science and medicine ...
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