Research Results in Biomedicine
Volume 9, Issue №3, 2023
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Genetics
The role of DNA methylation in lung cancer (review)
Background: Lung cancer has been a difficult-to-treat disease for decades, despite the efforts of oncologists and pharmaceutical companies. One of the reasons for this is the heterogeneity of the ...
Outcomes of ROHs (runs of homozygosity)/LCSHs (long contiguous stretches of homozygosity) spanning the imprinted loci of chromosomes 7, 11 and 15 among children with neurodevelopmental disorders
Background: Runs of homozygosity or long contiguous stretches of homozygosity (ROHs/LCSHs) are common in the human genome. ROHs/LCSHs spanning the imprinted loci have been previously associated with neurodevelopmental disorders. ...
Analysis of polymorphic variants of serotonin and gamma-aminobutyric acid receptor genes in patients with type 2 diabetes mellitus
Background: Type 2 diabetes mellitus (T2DM) is an expanding global health problem of the 21st century. There has been a global increase in the number of patients with T2DM. ...
Associations of polymorphic variants of candidate genes with the development of H. pylori-negative duodenal ulcer in residents of the Central Chernozem region of Russia
Background: Peptic ulcer disease (PUD) is a chronic recurrent disease that occurs with alternating periods of exacerbation and remission, the leading manifestation of which is the formation of a ...
Pharmacology
Stress-protective activity of Astragalus physodes extract on the model of «social» stress
Background: In recent decades, in the conditions of human existence, special attention has been paid to the problem of stress and the body's response to the impact of stress ...
Effect of pyrimidine derivative on cytokine levels in experimental generalized staphylococcal infection
Background: To date, bacterial infections caused by microorganisms characterized by antibiotic resistance are one of the leading causes of the protracted course of infectious and inflammatory diseases that occur with ...
Medicine (miscellaneous)
Features of intestinal microbiota diversity in elderly patients with metabolic disorders (literature review)
Background: Currently, the proportion of elderly patients is increasing all over the world (more than 20% of patients over the age of 60 in the Russian Federation), most of ...
Biological age as a risk factor for ophthalmological complications in type 2 diabetes mellitus
Background: An increase in the incidence of type 2 diabetes mellitus in many countries is simultaneously accompanied by an increase in the frequency of diabetic retinopathy, which is the ...
Effects of sarcopenia on hemodynamics in patients with cardiovascular diseases and pathological aging
Background: The number of patients with comorbid pathology and geriatric syndromes, particularly sarcopenia, increases with age. For the diagnosis of sarcopenia, the method of bioimpedance analysis with an ...
Dynamics of detection of narcotic compounds for 2013-2021: a case study of the Republic of Bashkortostan
Background: The consumption of psychoactive substances remains an urgent problem for modern society. The convenient geographical location on the way from China to central Russia and Europe makes ...
