ORGANOMETRIC PARAMETERS OF RATS’ THYROID GLAND IN THE READAPTATION PERIOD AFTER 60-DAY ADMINISTRATION OF TARTRAZINE AND MEXIDOL
In the course of an organometric experiment with 245 white outbred mature male rats it was found that the use of 5% mexidol solution as a corrector (50 mg/kg body weight) results in smoothing changes in organometric parameters of the thyroid gland in mature rats in the period of readaptation caused by 60-day daily intragastric administration of tartrazine. The intensity and duration of the correcting effect of mexidol under experimental conditions were greater in the group using tartrazine with a dosage of 750 mg/kg and decreased at increasing its administered dose up to 1500 mg/kg body weight.
Morozov VN, Morozova EN. Organometric parameters of rats’ thyroid gland in the readaptation period after 60-day administration of tartrazine and mexidol. Research Result. Medicine and Pharmacy Series. 2015;1(3): 28-35 (In Russian). DOI: 10.18413/2313-8955-2015-1-3-28-35
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