Research Results in Biomedicine
Volume 10, Issue №3, 2024
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Genetics
Mycobacterium tuberculosis gene variants associated with drug resistance to fluoroquinolones (literature review)
Background: The spread of M. tuberculosis drug resistance to fluoroquinolones poses a threat to their long-term clinical efficacy. Understanding the mechanisms of formation of drug resistance to ...
Relationship between polymorphism rs1546155 of the GGT7 gene and the risk of ischemic stroke
Background: Since oxidative stress plays a role in the pathogenesis of ischemic stroke (IS), it is important to investigate the molecular mechanisms contributing to redox homeostasis and ...
Circulating platelet-derived microRNAs as potential biomarkers of STEMI in patients with hypertension
Background: Circulating extracellular platelet-derived microRNAs have been actively studied over the last decade as promising biomarkers of cardiovascular disease (CVD), since platelet activation plays a key role ...
Assessment of the relationship between marriage and migration characteristics of the population of the Belgorod region in dynamics over 130 years
Background: The importance of studying the dynamics of the population-demographic structure of the population of the south of Central Russia over several generations dictates the need to ...
Geno-phenotypic features of cystic fibrosis in Russian children from the Chechen and Karachay-Cherkess Republics
Background: Cystic fibrosis (CF) is an autosomal recessive disease that occurs with a frequency of 1:1,500 to 1:5,000 newborns, according to the World Health Organization. In the ...
Pharmacology
Effects of taftsin-pro-gly-pro peptide on heart rate variability indices in rats in different motor activities
Background: The cardiotropic effects of a synthetic peptide with the anxiolytic activity of taftsin-Pro-Gly-Pro (taftsin-PGP) under stress was investigated. Previously, the effect of this peptide on the state ...
Selection of rational tools for the analysis of polyphenols of sandy everlasting flowers and artichoke leaves in the complex of pharmacological studies
Background: Pathology of the hepatobiliary system includes a heterogeneous group of diseases of the liver and biliary system caused by viral, bacterial and parasitic infections, neoplasms, toxic chemicals, ...
Medicine (miscellaneous)
LHCGR gene variants are associated with ovarian response and miscarriage risk following fresh and frozen embryo transfer
Background: Currently, infertility is a widespread problem. Despite recent advances in assisted reproductive technologies, success rates still need to be improved. Understanding patients' variability and addressing it ...
Seasonal changes in students' sleep quality as predictors of «adaptation» insomnia
Background: Sleep disorders occur even at a young age and may result from environmental factors such as circannual fluctuations in hormonal background and social sleep restriction, leading ...
Gerontological features of the effect of the new coronavirus infection on the interleukin profile, inflammation and endogenous intoxication in mature and elderly patients with coronary heart disease
Background: Coronary heart disease (CHD) is considered as an independent risk factor for COVID-19, however, the indicators of inflammation and endogenous intoxication in patients with CHD 3-4 ...
