Research Results in Biomedicine
Volume 12, Issue №3, 2026
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Genetics
Impact of the angiotensin-converting enzyme 2 gene polymorphism on essential hypertension in the southern region of Bangladesh
Background: Hypertension (HTN) is a major global health issue influenced by genetic, environmental and demographic factors. The angiotensin-converting enzyme 2 (ACE2), important for blood pressure regulation, has ...
Polymorphisms of the aquaporin-1 gene associated with the fetal growth retardation development
Background: The study of the insufficient fetal growth causes remains one of the priorities in modern obstetrics. In the absence of widely recognised maternal risk factors, genetic ...
Role of the genes of glutathione-related enzymes involved in the antioxidant defense in survival and longevity
Background: Human longevity is characterized by maintaining cellular homeostasis in the age-related changes of the internal conditions. The efficiency of many redox endogenous processes depends on the ...
Pharmacology
Secondary metabolites of Reynoutria sachalinensis – a potential reserve of pharmacological drugs (review)
Background: This literature review focuses on the perennial herbaceous plant Reynoutria sachalinensis, which belongs to the Polygonaceae family. This species is considered invasive in many countries, and ...
Immunomodulatory effect of saponins from Agave brittoniana subsp. brachypus (Trel.) in a model of fetal alcohol toxicity
Background: Prenatal exposure to ethanol can result in immunosuppression in the foetus due to alterations in tissue architecture and cellular composition, as well as reduced immune system ...
Anti-Proliferative Activity of [Cu(phen)(D-threo)]NO₃ + F⁻ Against Colorectal and Ovarian Cancer Cell Lines
Background: Cancer is a malignant disease characterized by the uncontrolled division of cells, leading to the invasion and destruction of healthy tissues. Copper(II) complexes of 1,10-phenanthroline and ...
Medicine (miscellaneous)
Genetic predictors of efficacy and safety of clozapine therapy (review)
Background: Clozapine remains an indispensable antipsychotic for patients with treatment-resistant schizophrenia, but its use can induce adverse drug reactions. Genetic characteristics of patients explain interindividual variability in ...
Personalized telerehabilitation in the context of modern determinant of gerontological care (review)
Background: Stroke is one of the leading causes of disability in the elderly. Modern healthcare systems face workforce shortages and limited access to inpatient rehabilitation, especially in remote ...
Inhibitors of intracellular signaling affect the production of soluble endoglin by JEG-3 trophoblast cells upon interaction with NK cells
Background: The cytotoxic activity of natural killer (NK) cells is essential for the proper invasion of trophoblasts into the uterine mucosa. Endoglin (Eng) plays an important role ...
Prognostic biomarkers of low-energy fractures in older patients
Background: Low-energy fractures are common among elderly and senile patients, but the predictive ability of individual blood biomarkers in relation to these fractures remains poorly understood. The ...
