Research Results in Biomedicine
Volume 4, Issue №4, 2018
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Genetics
Association of the ITGB3 gene T1565C polymorphism with the development of atherosclerosis and in-stent restenosis in patients with stable coronary artery disease
Background: Today, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery disease (CAD). Despite all technical advances in stent designs and techniques, in-stent restenosis (ISR) remains ...
Study of IL5, IL1 and TNFα genes polymorphisms in the predisposition to chronic polypoid rhinosinusitis
Background: Chronic rhinosinusitis (CRS) is a common disease of the nose and paranasal sinuses with a protracted, relapsing course, whose treatment is often ineffective. Two forms of chronic ...
Population genetic characteristics and genetic epidemiological research of candidate genes associations with multifactorial diseases
Background: When studying associations of candidate genes with multifactorial diseases, the formation of samples for research is important. One of the factors that should be considered in the formation ...
Pharmacology
Perspective materials for drug delivery in the ophthalmic dosage form: a short review of polymers for electrospinning
Background: The traditional ophthalmological dosage forms have a low bioavailability, a rapid precorneal clearance and a low corneal permeability. The gelling system or system with a prolonged action (prolonged ...
Pharmacological correction of metabolic disturbances in experimental acute pancreatitis on the background of chronic alcohol intoxication
Background: Acute pancreatitis ranks third among all acute surgical diseases of the abdominal cavity and is one of the important unresolved problems in emergency surgery. The aim of the ...
Development of the composition and analysis of suppositories of antihemorrhoidal action
Background: The study is devoted to the development of composition and assessment of the quality of two-layered suppositories with an oil extract of rowanberries (Sorbus aucuparia) ...
Medicine (miscellaneous)
Effects of KED peptide on connexin and sirutin expression in atherosclerosis and restinosis in elderly people
Background: Despite the wide range of application of the KED peptide, the molecular mechanisms of its action are still not fully understood. The aim of the study: To study ...
The value of determining concentrations of calcidiol and vascular endothelial growth factor to predict non-developing pregnancy
Background: Non-developing pregnancy is one of the most difficult medical and social problems of modern obstetrics and gynecology, which has no tendency to decrease. Previously occurred non-developing pregnancy is ...
The influence of operational stress on the progression of cognitive dysfunction in middle-aged and senior patients with ischemic heart disease and valvular dysfunction
Background: The relevance of this study is determined by the search for reserves to improve and increase the quality of life of patients undergoing open-heart surgery, especially the elderly ...
Nonpsychotic mental disorders in patients with benign hypersplasia of the prostate gland (clinic and therapy)
Background: Benign prostatic hyperplasia (BPH) is the most common disease of the genitourinary system in elderly men. It hampers social functioning and reduces the quality of life. The aim ...
