Research Results in Biomedicine
Volume 9, Issue №4, 2023
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Genetics
Prospects for the investigation of retroelements for COVID-19 therapy (review)
Background: The search for methods to detect COVID-19 using genetic advances can become the basis for an effective fight against this viral infection. Targeted therapy using non-coding RNAs ...
Study of microbiome aberrations in patients with irritable bowel syndrome with diarrhea by next-generation sequencing
Background: Irritable bowel syndrome (IBS) is a common functional disorder of the gastrointestinal tract (GIT). Despite the prevalence of this disease, our understanding of the etiology remains limited. ...
The link of single nucleotide polymorphism rs4880 of the SOD2 gene to the development of microvascular complications of type 2 diabetes mellitus
Background: The superoxide dismutase 2 (SOD2) gene encodes a mitochondrial enzyme whose main function is to convert superoxide anion to hydrogen peroxide. A genetically determined decrease in the ...
Clinical and genetic characteristics of cystic fibrosis in the Republic of Bashkortostan
Background: According to estimates of the World Health Organization, 40-50 thousand children worldwide are born each year with cystic fibrosis (CF), a monogenic disease with genetic heterogeneity and ...
NOS3 gene polymorphism variants and main characteristics of heart rate variability in Northerners
Background: Heart rate variability as a demonstration of autonomic nervous system function reflects human health and well-being. By monitoring heart rate variability indices and focusing on the imbalance ...
Pharmacology
Seasonal periodontal microcirculation by combined stress in rats corrected with complex phytoadaptogen
Background: One of the negative inducers of the internal environment is inflammation; amongst external factors the most significant is polyetiological stress. One of the promising pharmacological methods of ...
Curcumin Ameliorates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Endoplasmic Reticulum Stress in The Liver
Background: Nonalcoholic fatty liver disease (NAFLD) is a chronic pathological condition of the liver due to excess triglyceride accumulation in hepatocytes. The antioxidant properties of curcumin improve lipid ...
Medicine (miscellaneous)
Assessment of malnutrition risk in post-stroke patients: a systematic literature review
Background: Stroke is one of the main causes of death, especially when associated with malnutrition. Assessment of nutritional status in all stages of the disease is therefore mandatory ...
Comorbidity and syntropy of benign proliferative diseases of the female reproductive system: non-genetic, genetic, and epigenetic factors (review)
Background: Benign proliferative diseases of the female reproductive system (endometriosis, endometrial hyperplasia, and uterine leiomyoma) are comorbid and often occur together. The aim of the study: To establish ...
Features of the psychological deficit profile of elderly patients with age-associated comorbid cardiopathology
Background: With increasing age, there is an increased likelihood of cognitive impairment, anxiety-depressive syndrome among patients with comorbid arterial hypertension (AH) and coronary heart disease (CHD), which are ...
