Research Results in Biomedicine
Volume 11, Issue №4, 2025
Genetics
Common CNVs modulate phenotypes in neurodevelopmental disorders (autism and intellectual disability): focus on SHANK3 and CHAMP1
Background: Common copy number variations (CNVs) are rarely considered as causative in genomic research dedicated to uncovering mechanisms of neurodevelopmental diseases. However, analyzing complex systems of interactions ...
Frequency, spectrum, and functional significance of mutations in the MIR-142 gene in diffuse large B-cell cell lymphoma
Background: MIR-142 is the only human microRNA gene that is highly mutated in diffuse large B-cell lymphoma (DLBCL). Early studies of abnormalities in this gene were based on ...
The relationship between the genetic determinants of SHBG and the hormonal profile of patients with uterine fibroids
Background: Uterine fibroids are benign hormone-dependent tumors that affect the muscle layer of the uterus and are common in women of reproductive age. Genetic factors are important ...
Pharmacology
Chemical composition and antimicrobial activities of Boesenbergia xiphostachya
Background: Boesenbergia xiphostachya is a rare species, recently discovered in Vietnam. Information about the chemical compositions and biological properties of distinct parts of this plant ...
An investigation into the acute and sub-chronic toxicityof ethanol extract of Ardisia sylvestris Pitard leaves in vivo
Background: The global rise in the usage of herbal medicine has prompted a critical examination of its safety. Despite widespread assumptions of safety, there remains a need for ...
