Keyword "DIABETES" found in the following publications:
Background: Glycogen synthase 2 (GYS2) catalyzes a key step in glycogenesis in the liver. Loss-of-function mutations in the GYS2 ...
ADAPTIVE DESIGN IN CLINICAL DEVELOPMENT OF NEXT-IN-CLASS DRUGS
Introduction: The next-in-class drugs are the original drugs that by chemical structure and mode of action similar to their ...
Relevance. Glutamate-cysteine ligase (GCL) is the first enzyme of the glutathione cycle, intra- and extracellular antioxidant, whose impaired metabolism ...
Background: Type 2 diabetes mellitus (T2DM) is an expanding global health problem of the 21st century. There has been ...
APELIN-ADDITIONAL MARKER OF INSULIN RESISTANCE
The purpose of the present study was to determine the correlations between the state of carbohydrate metabolism and concentrations of ...
In the course of the study, there were examined 40 patients with hypertension, including 19 patients with associated type 2 ...
GENETIC VARIATION OF ERN1 AND SUSCEPTIBILITY TO TYPE 2 DIABETES
Background: The endoribonuclease IRE1 (ERN1) is an important sensor for the endoplasmic reticulum unfolded protein response (UPR), and its ...
The purpose of the research was to assess the intima media thickness of the common carotid artery (IMT CCA) ...
Introduction: A promising compound for the treatment of inflammatory periodontal diseases is benzofuracaine (BFC). BFC has pronounced anti-inflammatory, analgesic, reparative, hypoglycemic and ...
Introduction: The search for and development of new highly active medications and their combinations of the appropriate direction of ...
Introduction: We glad to introduce several variants of pharmacological correction of ischemic hepatic injury by imidazoline I2 receptor agonistС7070.
...CONTRIBUTION OF RS11927381 POLYMORPHISM OF THE IGF2BP2 GENE TO THE PATHOGENESIS OF TYPE 2 DIABETES
Background: Pancreatic beta-cell dysfunction, along with the insulin resistance of peripheral tissues, is a key element in the ...
Background: Ageing is an evolutionary long-term biological process that leads to a decline in the functional capacity ...
PHYTODRUGS, ANALYSIS OF RUSSIAN FEDERATION PHARMACEUTICAL MARKET
Up to know plant raw material and drugs based on it (tinctures, extracts, highly purified extracts, individual substance drugs) ...
Background: The high incidence of diabetes mellitus in modern conditions dictates the need to search for new, ...
EFFECTS OF DIMEPHOSPHONE ON SKIN SURVIVAL IN CONDITIONS OF REDUCED BLOOD CIRCULATION
Introduction: The search for and creation of drugs with dermatoprotective and metabotropic activity is one of the priorities of modern ...
MANIFESTATION OF THE BLOOD RESPIRATORY FUNCTION IN THE SETTING OF HYPERGLYCEMIA
It was determined that the red blood respiratory function was depressed in middle aged men with type 2 diabetes mellitus. ...Background: Currently, the proportion of elderly patients is increasing all over the world (more than 20% of patients over ...
Background: Phosphatidylethanolamine N-methyltransferase (PEMT) is the enzyme of lipid metabolism that catalyzes the conversion of phosphatidylethanolamine to phosphatidylcholine ...
The purpose of the research is to assess the fractalkine and asymmetric dimethylarginine (АDМА) levels in patients with coronary artery ...
Background: Numerous epidemiological studies have shown the role of unhealthy diet, smoking, low physical activity, and psycho-emotional stress in ...
BIOLOGICAL AGE AS A RISK FACTOR FOR OPHTHALMOLOGICAL COMPLICATIONS IN TYPE 2 DIABETES MELLITUS
Background: An increase in the incidence of type 2 diabetes mellitus in many countries is simultaneously accompanied by an ...
Relevance. Insulin and insulin-like growth factor-1 are regarded as a single signal system that regulates the metabolism and processes ...
Background: Diabetes is a major global disease with a high mortality rate.The impact of exercise on bone tissue ...
PECULIARITIES OF THE OXIDATIVE STATUS IN ELDERLY PATIENTS WITH TYPE 2 DIABETES MELLITUS
Background: With age, diabetes mellitus becomes a frequent health problem in many people. However, to date, various clinical and ...
Experiments in rats showed that the 9-diethylaminoethyl-2-(3,4-dioxyphenyl)-imidazo-[1,2-a]-benzimidazole dihydrobromide with the provisional name of enoxifol (0.94 – 15 mg/kg), rexod (recombinant ...
Background: The superoxide dismutase 2 (SOD2) gene encodes a mitochondrial enzyme whose main function is to convert superoxide ...
