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Research Results in Biomedicine

Volume 5, Issue №1, 2019
Genetics

Using the method of Multifactor Dimensionality Reduction (MDR) and its modifications for analysis of gene-gene and gene-environment interactions in genetic-epidemiological studies (review)

Background: In the genetic and epidemiological study of multifactorial signs (diseases), an important task is to assess the genetic and genetic-environmental interactions associated with the ...

First report on a 20qh+ heteromorphism characterized by molecular cytogenetics as amplification of D20Z1 sequences

Background: Chromosomal heteromorphisms (CHMs) in human are still understudied. This is partially due to the fact that heterochromatic regions are not well documented in human ...

Molecular cytogenetic study of preterm infants: genomic anomalies detection

Background: The intensive implementation of molecular cytogenetic technologies into medical practice has made it possible to detect genomic rearrangements with previously unavailable resolution (molecular karyotyping), ...
Pharmacology, clinical pharmacology

Comparative evaluation of the effectiveness of DMAE derivative 7-16, carbamilated darbepoetin and substance C7070 in correction of hypertensive neuroretinopathy in rats

Background: Increasing the effectiveness of drug therapy for hyperintensive neuroretinopathy is one of the important tasks of pharmacology and ophthalmology. The aim of the study: To assess the effectiveness ...
Clinical Medicine

Signal molecules involved in the formation of new nerve endings in endometriosis (review)

Background: The mechanism of the development of pain syndrome in endometriosis is heterogeneous. The study has been established that in the recently formed endometriotic implants there are neoneurogenesis processes, ...

Anorexia nervosa: prevalence, diagnostic criteria and psychosomatic relations (review)

Background: The problem of anorexia nervosa has become more and more important in recent years due to the increasing incidence ...

Expression of MMP proteins in the aging of the myocardium in normal conditions and dilated cardiomyopathy

Background: Matrix metalloproteinases (MMP), their TIMP inhibitor, adhesion molecules, sirtuins, and apoptosis markers are among the signaling molecules that may have an important prognostic value in dilated ...

Complex geriatric assessment of osteoarthrosis of knee joints in the senior age

Background: The diseases of the musculoskeletal system are a serious problem among patients of older age groups, as they can lead to ...