Research Results in Biomedicine
Volume 11, Issue №2, 2025
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Genetics
Clinic-laboratory blood parameters and the contribution of renin-angiotensin system gene polymorphisms in pregnant women with preeclampsia
Background: Preeclampsia (PE) is a pregnancy-related condition linked to hypertension and proteinuria. It is a major cause of maternal and perinatal mortality. The aim of the study: ...
The role of transposable elements in formation of evolutionary diversity of eukaryotic proteomes (review)
Background: Transposable elements make up a significant proportion of eukaryotic genomes and are objects of modern genetic research, including in the design of targeted tumor therapies. For ...
Associations of polymorphic loci of candidate genes with the level of sex hormones in patients with endometrial hyperplasia
Background: Endometrial hyperplasia (EH) is one of the most common gynaecological conditions in which sex hormones play an important role in the pathophysiology. The occurrence of hyperestrogenia against ...
Pharmacology
In-silico insights into α-Synuclein mediated pathology of Parkinson’s disease using molecular docking and molecular dynamics simulation studies
Background: The precise cause of neuronal loss in Parkinson's disease (PD) is multifactorial, involving genetic and environmental factors. Genetic mutations, affecting many proteins such as α-Synuclein, Leucine-rich repeat ...
Investigating Phytochemical Constituent and Anti-Anemic Properties of Polyphenol-Rich Extract from Carica papaya Leaves in a Rat Model
Background: Anemia, affecting 24.8% of the global population, is a common blood disorder caused by deficiencies in haemoglobin or red blood cells due to factors like chronic illness, ...
Metabolic and functional effects of complex therapy of renal and cardiovascular pathology with sodium-glucose cotransporter type 2 inhibitors in patients with diabetes mellitus and Covid-19 (review)
Background: Studying the mechanisms of development of chronic kidney pathology and concomitant disorders of the cardiovascular system in patients with type 2 diabetes mellitus (DM2) and its combination ...
Medicine (miscellaneous)
Effect of Cigarette Smoke on Female Reproductive System: A Sytematic Review
Background: The closest toxic exposure is cigarette smoke, and nowadays smokers are not only men but also women. Although the number of smokers has dropped, cigarettes remain ...
Suicidalbehaviorandcomorbidsomaticdiseases (review)
Background: Suicidal behavior continues to be one of the most acute medical problems, the relevance of which continues to remain at a high level. The article presents ...
The etiology and pathogenesis of atherosclerosis: modern insights and age-dependent aspects (review)
Background: Atherosclerosis is a leading cause of morbidity and mortality worldwide. It is a systemic pathological process attributed to the deposition of atherogenic lipoproteins in the intima of ...
Effect of visual impairment and arterial hypertension on the prevalence of geriatric syndromes in elderly patients
Background: Arterial hypertension and visual impairment due to various ophthalmopathologies are common age-related diseases, but their combined effect on the geriatric profile of patients has not been practically ...
