Research Results in Biomedicine
Volume 8, Issue №3, 2022
PDF
Genetics
Genetic variation of ERN1 and susceptibility to type 2 diabetes
Background: The endoribonuclease IRE1 (ERN1) is an important sensor for the endoplasmic reticulum unfolded protein response (UPR), and its activation happens as a result of the accumulation of unfolded ...
C9orf16 (BBLN) gene, encoding a member of Hero proteins, is a novel marker in ischemic stroke risk
Background: Ischemic stroke (IS) is the leading cause of death and disability worldwide. Chaperone proteins protect brain cells from the ischemic damage by restoring the structures of damaged proteins. Chaperone ...
Study of the cytokine genes SNPs association with the characteristics of the immunological status of children with recurrent respiratory infection
Background: Herpesvirus infections are one of the most common human infections that play a special role in children with recurrent respiratory infection cohort formation. The immunological status of such ...
Genetic markers of severe preeclampsia
Background: In modern medicine, close attention is paid to the issues of reducing maternal morbidity and mortality, to the structure of which hypertensive disorders of gestation, especially preeclampsia, make ...
Pharmacology
Studies to elucidate the effect and antiapoptotic mechanism of 2-ethyl-3-hydroxy-6-methylpyridine-n-acetyltaurinate in a rat model of retinal ischemia–reperfusion
Background: The study of possible ways of effective correction of retinal ischemia-reperfusion injury, which accompanies a number of eye diseases, is relevant today. The aim of the study: To study ...
In silico identification of the potential natural inhibitors of SARS-CoV-2 Guanine-N7 methyltransferase
Background: The outbreak of the COVID-19 pandemic caused by the SARS-CoV-2 has triggered intense scientific research into the possible therapeutic strategies that can combat the ravaging disease. One of ...
Correction of mitochondrial dysfunction with cinnamic acids in experimental hypercytokinemia
Background: Mitochondrial dysfunction is an essential component of the hypercytokine neurotoxicity pathogenesis and is a promising pharmacotherapeutic target. The aim of the study: To evaluate the effect of cinnamic acids ...
Medicine (miscellaneous)
Abnormal uterine bleeding: etiology and pathogenesis (descriptive review)
Background: Despite advances in medicine, uterine bleeding remains a well-known medical problem. Abnormal uterine bleeding has a negative impact on the physical, emotional, social, incl. material well-being of the ...
Features of postural balance in working women aged 60-69
Background: The formation of the state policy for optimizing healthy and active aging, aimed at creating an incentive for older people to work longer, requires new knowledge about the ...
Effect of melanocortin neuropeptides on the level of apoptotic and neurotrophic factors under «social» stress
Background: Currently, scientific papers reflecting the results of studying the pathological influence of stress factors, including "social" stress, on various body systems are of particular interest. It has been ...
