Research Results in Biomedicine
Volume 1, Issue №4, 2015
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Pharmacology
THE ROLE OF MITOCHONDRIAL ATP-DEPENDENT POTASSIUM CHANNELS IN THE CARDIOPROTECTIVE EFFECT OF NICORANDIL ON THE MODEL OF CORONARY OCCLUSIVE MYOCARDIAL INFARCTION
The paper presents the results of a study of the antiischemic effectiveness of nicorandil (1,8 mg/kg) on the model of coronary occlusive myocardial infarction in rabbits. The coronary occlusion in ...
ENDOTHELIO-AND CARDIOPROTECTIVE EFFECTS OF HMG-Co-A REDUCTASE IN ENDOTOKSIN-INDUCING ENDOTELIAL DYSFUNCTION
The use of inhibitors of HMG-Co-A reductase inhibitor Simvastatin, Atorvastatin, Rosuvastatin and nanoparticulated Rosuvastatin on the background modeling of endotoxin-induced pathology through introduction of strain 603 Staphylococcusaureus leads to the ...
CORRECTION OF ADMA-INDUCED PREECLAMPSIA WITH THE USE OF PHOSPHODIESTERASE 5 AND SELECTIVE INHIBITOR OF ARGINASE II ZB49-0010
Simulation experimental ADMA-like preeclampsia was carried out by administering the rats with L-NAME during 14-20 days of pregnancy. In animals, there was an increase in blood pressure, proteinuria, impaired microcirculation ...
SIMULATION OF TOTAL BRAIN ISCHEMIA IN RATS
This paper deals with the study of the dependence of psycho neurological deficit in rats on the severity of brain damage, conducted on the four-vascular models of total cerebral ischemia. ...
PHARMACOLOGICAL PRECONDITIONING WITH NICORANDIL AS A POSSIBILITY OF INCREASING THE STABILITY OF TISSUES OF THE RETINA TO ISCHEMIA IN AN EXPERIMENT
In laboratory rats, we formed an ischemic damage by providing mechanical pressure (110 mm Hg) to the anterior chamber for 30 minutes. The experiment has revealed the fact that nicorandil ...
Medicine (miscellaneous)
CLINICAL EFFICIENCY OF AZILEKT IN THE THERAPY OF PRIMARY PROGRESSING MULTIPLE SCLEROSIS
Multiple sclerosis − the chronic multifactorial progressing autoimmune disease of the central nervous system developing at any age, but mainly in young people. One of the factors of progression, along ...
THE THERAPY OF MULTIPLE SCLEROSIS WITH NUKLEO-СMF FORTE AND PK-MERZ MULTIDIRECTIONAL DRUGS
Multiple sclerosis − the multifactorial autoimmune disease affecting the head and spinal cord, demanding application in therapy of medicines of multidirectional action. In the group of patients, we used the ...
PHARMACOLOGICAL CORRECTION OF IMMUNE DISORDERS IN PATIENTS WITH CHRONIC HEART FAILURE AND ISCHEMIC HEART DISEASE
Currently, there are few data on the effect of cardiovascular drugs on the immune status of patients with heart failure (HF). This paper provides information on the impact of ß-adrenergic ...
COGNITIVE IMPAIRMENT IN PATIENTS WITH IDIOPATHIC SYMMETRICAL CALCIFICATION OF BASAL GANGLIA
Cognitive impairment is a subjectively and/or objectively detectable deterioration of cognitive functions (such as speech, memory, gnosis, praxis, thinking, etc.) compared with the initial individual or middle age ...
PECULIARITIES OF POLYNEUROPATHY IN THE PERIPHERAL T-CELL LYMPHOMA WITH CYTOSTATICS
The number of patients with malignant tumors has increased steadily. Every year more than 12 million new cases are registered, including non-Hodgkin's lymphoma. A modern problem in medicine consists of ...
METHODOLOGY ANALYSIS MAPPING ELEMENTAL COMPOSITION OF MYOCARDIAL TISSUE WITH A SCANNING TRANSMISSION MICROSCOPY.
The article presents a method for the quantitative determination of the distribution of concentrations of chemical elements in a biological sample. The authors suggest a method of mapping ...
Archive categories
MICROSCOPIC FEATURES OF BUCCAL EPITHELIUM OF THE INDIAN STUDENTS STUDYING AT BELGOROD STATE NATIONAL RESEARCH UNIVERSITY
The authors studied the microscopic features of buccal epithelium of the Indian students studying at Belgorod State National Research University. The appearance in the buccal mucosa epithelium of single leukocytes, ...
MICROSCOPIC FEATURES OF BUCCAL EPITHELIUM IN SMOKING STUDENTS OF INDO-DRAVIDIAN RACE (BY E. HOOTON)
We have studied the microscopic features of buccal epithelium in smoking students of Indo-Dravidian race. In the epithelial cells of the mucous cheek surface of smoking students we revealed the ...
THE RELATIONSHIP BETWEEN PARAMETERS OF THE PEYER'S PATCHES OF THE SMALL INTESTINE IN INTACT RATS
This paper deals with the study of the relationship between parameters of the Peyer’s patches of the small intestine in intact rats of different age groups. The correlation analysis revealed ...
MORPHOMETRIC STUDY OF HIPPOCAMPAL NEURONS IN CHRONIC IMMOBILIZATION STRESS
Hippocampus ensures the implementation of the memory mechanisms, behavioral reactions, including avoidance of stress, aversive effects etc. The study was performed on the material of 20 male Wistar rats weighing ...
ANALYSIS OF WORLD AND RUSSIAN TRENDS IN CANCER INCIDENCE IN THE TWENTY-FIRST CENTURY
The review analyses and compares the main materials of the International Agency for Research on Cancer (cancer on 5 continents) and statistic indicators characterizing the state of cancer ...
OPTIMIZATION OF INFORMATION SUPPORT FOR PHARMACIES IN THE FIELD OF PHARMACEUTICAL AID TO CHILDREN WITH ARTHROPATHY
The paper presents an analysis of information awareness of pharmaceutical personnel on aspects of pharmaceutical aid to children with joint diseases; we analyzed the product portfolio of medicines for treating ...
MARKET RESEARCH OF RUSSIAN MEDICINAL PRODUCTS USED FOR TREATMENT OF ACUTE RESPIRATORY VIRAL INFECTION IN PREGNANT WOMEN
This paper deals with the conducted market research of Russian medicinal preparations used for treatment of acute respiratory viral infection in pregnant women.
DEVELOPMENT PROSPECTS OF NATUROTSEVTIKA
Today, humanity is experiencing another round of interest in naturaceutics. The study of new types of plant materials and their introduction into the official medicine in the form of drugs ...
MARKETING ANALYSIS OF THE MARKET OF MEDICINES USED IN THE TREATMENT OF DYSTONIA IN CHILDREN
The authors conducted a market research of the Russian market of medicinal preparations used in the therapy of vegetovascular dystonia. The results of the content analysis demonstarte that 1198 medicinal ...
STUDYING THE EFFICIENCY OF THE ESSENTIAL DRUGS SUPPLY PROGRAM IN BELGOROD REGION
The authors have studied the efficiency of the Essential Drugs Supply Program (EDSP) in Belgorod Region. After reviewing the results of inspections in medical institutions and the data of the ...
OPTIMIZATION OF METHODS OF STEROID DRUG QUALITY CONTROL ON THE EXAMPLE OF GLUCOCORTICOSTEROIDS
This paper presents an original method for the analysis of corticosteroids with the use of reversed-phase high performance liquid chromatography. A mixture of 1% aqueous formic acid and ethyl alcohol ...
THE CHEMICAL STUDY OF THE ANTHOCYANINS IN OCIMUM BASILICUM L. HERB
Sweet basil − Ocimum basilicum L. contains a wide spectrum of biologically active compounds: essential oils, phenolic compounds, including flavonoids and anthocyanins. The violet variety is a rich ...
ANALYTICAL CHARACTERISTICS OF CARBON DISULFIDE DERIVATIVES
This article is a literature review of modern methods of determining carbon disulfide when it is present in any objects in small quantities. Since taking into account the toxicity of ...
