Keyword "2" found in the following publications:
Background: Preeclampsia (PE) is one of the most serious pregnancy complications and is the leading cause of maternal and ...
Introduction: The review provides relevant information about arginase 2, the role of this enzyme in the formation of endothelial dysfunction ...
The author of the article focuses on the experience of Hannah Arendt's perception of Hegelian political philosophy as interpreted by ...
Introduction: Searching for new compounds with anti-anxiety activity resulting from the combination of privileged scaffolds is a promising direction ...
Background: One of the most common diseases of the female population is breast cancer (BC), which is ...
REPRODUCTION OF VOLUNTEER ACTIVITY OF YOUNG PEOPLE IN THE CONDITIONS OF UNCERTAINTY AND RISK
The article discusses the conditions, external and internal factors influencing the degree of implementation of the tasks necessary for the ...
Background: Breast cancer (BC) is a malignant breast tumor, which occupies a leading place both in the structure of ...
CONTRIBUTION OF RS11927381 POLYMORPHISM OF THE IGF2BP2 GENE TO THE PATHOGENESIS OF TYPE 2 DIABETES
Background: Pancreatic beta-cell dysfunction, along with the insulin resistance of peripheral tissues, is a key element in the ...
The relevance of this study is due to the need to develop the industrial sector in the EAEU countries and ...
Background: The authors note that special literature does not make mention of drugs for targeted, specific correction of retinal ...
This paper examines the effect of the National Plan 2010-2020 policy that focuses on the development of the ...
Background: Placental insufficiency (PI) is a key feature of pregnancies with fetal growth restriction (FGR). FGR is defined ...
MANIFESTATION OF THE BLOOD RESPIRATORY FUNCTION IN THE SETTING OF HYPERGLYCEMIA
It was determined that the red blood respiratory function was depressed in middle aged men with type 2 diabetes mellitus. ...THE STATE OF THE TOURIST B2C MARKET IN RUSSIA
The influence of the market economy on the tourism industry in Russia is great and it is impossible ...
Background: Glycogen synthase 2 (GYS2) catalyzes a key step in glycogenesis in the liver. Loss-of-function mutations in the GYS2 ...
Background: Chromosomal heteromorphisms (CHMs) in human are still understudied. This is partially due to the fact that heterochromatic ...
Introduction: According to statistical data, the tendency towards an increase in the number of patients with keloid and hypertrophic ...
TERMINOLOGY USE IN SCHOOL TEXTBOOKS: CORPUS ANALYSIS
The article presents the methods and results of the study that investigated the use of terminology in textbooks for ...
Background: HPV infection leads to an imbalance of pro- and anti-inflammatory cytokines, which contributes to the long-term persistence of ...
Background: Multidrug resistance bacteria are a serious problem for health specialists and all the people in the ...
Introduction: The search for new compounds with antihypoxic and cardioprotective effects among 3-oxypyridine derivatives is promising.
Research objectives: ...
Background: The superoxide dismutase 2 (SOD2) gene encodes a mitochondrial enzyme whose main function is to convert superoxide ...
Introduction: The present paper provides a study of the activity of the new 1,3-diazinon-4 derivatives and their acyclic precursors ...
Bacteriocins are ribosomally synthesized antibacterial peptides secreted by certain types of bacteria and are active against both closely related species,and ...
TRADITIONAL ASIAN EDUCATION AND EDUCATION 2.0: HOW CLOSE IS THE FIT?
This paper is situated in the global context where Asia is seeking to redefine itself as an entity with values ...
The purpose of the research was to assess the intima media thickness of the common carotid artery (IMT CCA) ...
GENETIC VARIATION OF ERN1 AND SUSCEPTIBILITY TO TYPE 2 DIABETES
Background: The endoribonuclease IRE1 (ERN1) is an important sensor for the endoplasmic reticulum unfolded protein response (UPR), and its ...
Background: According to statistics, the first place among the causes of death worldwide is occupied by cardiovascular diseases ...
ROLE OF OREXIN PEPTIDE SYSTEMINEMOTIONAL OVEREATINGINDUCED BY BRAIN REWARD STIMULATION IN FED RATS
Introduction: The purpose of this work was to prove that the reaction of food self-deprivation in “fed up” rats is ...
Background: Metabolic syndrome (MS) and its components are the reasons of the development and progression of cardiovascular ...
PROSPECTS FOR THE INVESTIGATION OF RETROELEMENTS FOR COVID-19 THERAPY (REVIEW)
Background: The search for methods to detect COVID-19 using genetic advances can become the basis for an effective ...
The paper presents results of a study of antioxidant (in vitro) and anti-ischemic effect of a number derivatives of 3-(2,2,2-trimethylhydrazinium) ...
- Use of selective inhibitors of arginase 2 in combination with tadalafil on in the course of modeling of homocysteine-induced endothelial ...
STRATEGIES FOR L2 LECTURE COMPREHENSION: AN INTERVENTION STUDY
The study reported in this article set out to investigate the effect of an intervention into the strategies for second ...
CONTINUITY OR RUPTURE? ON THE CONSTITUTIONAL ACTS OF THE GERMAN CONFEDERATION OF 1815 AND 1820
The article is devoted to the analysis of two main documents of the Constitution of the German Confederation – the Federal ...
Background: Arterial hypertension (AH) is the most common disease of the cardiovascular system. Intracellular chemical and oxidative stress, ...
The study aim was to explore pharmacological effects of 2-aminoaethansulfonic acid compounds in reperfusion-induced heart injury.
Materials and ...
EDUCATION BY 2030 AND 2035: FORESIGHT TECHNOLOGIES AND TELEOLOGY OF RISKS AND BENEFITS
 The article examines the content, goals and super-tasks of business foresight projects for the future of Russian education, created by ...
Introduction: Many anti-tumor drugs have a high potential for toxic damage to liver cells, which makes it necessary to ...
Background: Miscarriages are one of the most common complications of the first term of pregnancy. The rate of early ...
RUSSIA-2050: RESULTS OF THE SOCIOLOGICAL RESEARCH
The results of the complex sociological research of representations and expectations of citizens of Russia for 2050 are covered in ...
- The article presents the data about the characteristic parameters of the physical state of the human body. This data is ...
ARABIC IN THE LEAD-UP TO THE ARAB SPRING: FUSION OR DIFFUSION
This article aims to place the Arabic language in its recent historical context and proposes to describe the situation of ...
Introduction: The search for new compounds with cardioprotective activity amongst the 3-(2,2,2-trimethylhydrazinium) propionate derivatives looks promising.
Research objectives: ...
The art of the repressed is a relatively new and little-studied concept in scientific discourse, meaningfully referring to the history ...
ADAPTIVE DESIGN IN CLINICAL DEVELOPMENT OF NEXT-IN-CLASS DRUGS
Introduction: The next-in-class drugs are the original drugs that by chemical structure and mode of action similar to their ...
PHARMACOLOGICAL CORRECTION OF FETOPLACENTAL INSUFFICIENCY WITH FETAL GROWTH RETARDATION SYNDROME
Introduction: fetoplacental insufficiency (FPI) is an important problem of obstetrics. This pathological condition leads to the development of fetal ...
This paper deals with the study of correction of L-NAME-induced endothelial dysfunction by means of 3-(2,2,2-trimethylhydrazinium) propionate derivatives. We have ...
STUDY OF ANALEPTIC ACTIVITY OF TETRAHYDROPYRIDO [2,1-B] [1,3,5] TIADIAZINE DERIVATIVES
Abstract
Introduction: Our goal is to conduct an investigation of the analeptic activity of the tetrahydropyrido [2,1-b] [1,3,5] ...
In experiments on the isolated rat heart there were studied the effects of different doses (21.43 mg/kg/day and 85.72 ...
FIRST MOLECULAR CYTOGENETIC CHARACTERIZATION OF THE MMT 060562 MURINE BREAST CANCER CELL LINE
Background: Murine cell lines are working horses applied as model systems in multiple research studies in many laboratories. ...
DEVELOPMENT OF ECOLOGICAL TOURISM IN PROTECTED
The article discusses the prospects for the development of eco-tourism on the basis of specially protected natural territories of the ...
USE OF E-COMMERCE IN MODERN CONDITIONS OF DOMESTIC COMPANIES
The article covers the state and prospects of E-commerce development worldwide. The author provides some recommendations on how to improve ...
Introduction: The retinoprotective effect of the 11-amino acid fragment of darbepoetin PRK-002 on the models of hypertensive retinal angiopathy and ...
METAL-CONTAINING TAURINE COMPOUNDS PROTECT RAT’S BRAIN IN REPERFUSION-INDUCED INJURY
 Introduction: The study aim was to explore a neuroprotective action of magnesium (LKhT-317) and zinc (LKhT-318) taurine salts on experimental ...
Relevance. Insulin and insulin-like growth factor-1 are regarded as a single signal system that regulates the metabolism and processes ...
In the course of the study, there were examined 40 patients with hypertension, including 19 patients with associated type 2 ...
Introduction: Regardless of belonging of NSAIDs to one or another chemical group, they all have common side effects that ...
The purpose of the research is to assess the fractalkine and asymmetric dimethylarginine (АDМА) levels in patients with coronary artery ...
ABOUT TRENDS OF THE MANAGEMENT MODEL OF A MODERN UNIVERSITY
In an increasingly uncertain and unpredictable environment, the higher education system’s adherence to general trends in the development of ...
GENETIC MARKERS OF SEVERE PREECLAMPSIA
Background: In modern medicine, close attention is paid to the issues of reducing maternal morbidity and mortality, to the ...
MODERN APPROACHES TO PHARMACOTHERAPY OF COMMUNITY-ACQUIRED PNEUMONIA
Introduction: The study presents current views on the pharmacotherapy of community-acquired pneumonia (CAP). This study also describes in general ...
- The purpose of this article is to present the results of sociological research on a number of issues of modern ...
2Q14 DE NOVO INTERSTITIAL DELETION IN A GIRL WITH INTELLECTUAL DISABILITIES AND MALFORMATIONS
Background: Neurodevelopmental disorders have a prevalence of approximately 3% in the population, the genetic factor is involved in ...
MODERN GENOMICS IN STUDYING THE PROBLEMS OF HUMAN ADAPTATION TO CLIMATE IN NORTH SIBERIA
Background: Indigenous people of north Siberia live in some of the harshest natural conditions on Earth, experiencing prolonged ...
The purpose of this paper was to explore the social actor’s representation and find the themes in Imran ...
ON THE WAY FROM SARS-COV-SENSITIVE MICE TO MURINE COVID-19 MODEL
The coronavirus disease 2019 (COVID-19) is a master killer which appeared suddenly and which has already claimed more than 200,000 ...
Background: Type 2 diabetes mellitus (T2DM) is an expanding global health problem of the 21st century. There has been ...
Background: The outbreak of the COVID-19 pandemic caused by the SARS-CoV-2 has triggered intense scientific research into the possible ...
ABOUT THE ORIGIN OF THE ACROCENTRIC PART OF NON-ACROCENTRIC SATELLITED CHROMOSOMES IN HUMANS
 Background: Variants in size of the acrocentric short arms (acro-ps) are normally not reported and considered as chromosomal ...
CHOICE OF ANTIHYPERTENSIVE THERAPY IN HYPERTENSIVE PATIENTS WITH CRITICAL CORONARY ARTERY STENOSIS
Sixty patients with stages II-III AH were studied. ABPM was performed in all the patients. DBPP was assessed by the ...
Background: Numerous epidemiological studies have shown the role of unhealthy diet, smoking, low physical activity, and psycho-emotional stress in ...
Introduction: The aim of this study was to explore the antiarrhythmic activity of the new antiarrhythmic drug, succinic acid ester ...
Background: Genetic and environmental factors are involved in the development of chronic pancreatitis. The aim of the study: To determine ...
MAXIMUM TOLERANT DOSE AND ANALGESIC ACTIVITY OF PT1 PEPTIDE
Introduction: The article presents the results of the study of the maximum tolerant dose (MTD) and the analgesic activity of ...
Background: Bacterial vaginosis (BV) is a common vaginal infection that causes significant gynecological and obstetric morbidity. Despite ...
APELIN-ADDITIONAL MARKER OF INSULIN RESISTANCE
The purpose of the present study was to determine the correlations between the state of carbohydrate metabolism and concentrations of ...
Background: Phosphatidylethanolamine N-methyltransferase (PEMT) is the enzyme of lipid metabolism that catalyzes the conversion of phosphatidylethanolamine to phosphatidylcholine ...
PHYTODRUGS, ANALYSIS OF RUSSIAN FEDERATION PHARMACEUTICAL MARKET
Up to know plant raw material and drugs based on it (tinctures, extracts, highly purified extracts, individual substance drugs) ...
CORRELATION OF BIOCHEMICAL ABNORMALITIES WITH THE SEVERITY OF HOSPITALIZED COVID-19 PATIENTS
Background: Coronavirus Disease-19 (COVID-19) has a global impact. The laboratory assessments in Covid-19 illness help in better understanding the disease ...
Background: Herpesvirus infections are one of the most common human infections that play a special role in children with ...
HSPD1 GENE POLYMORPHISM IS ASSOCIATED WITH AN INCREASED RISK OF ISCHEMIC STROKE IN SMOKERS
 Background: Ischemic stroke (IS) is a leading cause of death and disability worldwide. Since the influence of vascular ...
The concomitant use of non-selective S-(2-boron-ethyl)-L-cysteine (BEC) arginase inhibitor with simvastatin, atorvastatin, rosuvastatin and nanoparticulated rosuvastatin on the background of ...
Background: Disturbances in the differentiation of cells and the processes of cellular renewal of the buccal epithelium, which occur ...
Background: Ischemic stroke (IS) is the leading cause of death and disability worldwide. Chaperone proteins protect brain cells from the ...
Relevance. Glutamate-cysteine ligase (GCL) is the first enzyme of the glutathione cycle, intra- and extracellular antioxidant, whose impaired metabolism ...
Background: The study of possible ways of effective correction of retinal ischemia-reperfusion injury, which accompanies a number of eye ...
LITERATURE AND EMPTINESS: THE STRATEGIES OF DESTRUCTIVENESS IN RUSSIAN LITERATURE OF THE SILVER AGE
The article deals with the main variants of destructive strategies implemented by the Russian literature of the 19-20th centuries in relation ...
