Keyword "POLYMORPHISM" found in the following publications:
SELECTION OF POLYMORPHIC LOCI FOR ASSOCIATION ANALYSIS IN GENETIC-EPIDEMIOLOGICAL STUDIES
Background. The study of the role of hereditary factors in the formation of multifactorial signs is relevant, and ...
Background: Bacterial vaginosis (BV) is a common vaginal infection that causes significant gynecological and obstetric morbidity. Despite ...
Background: Primary open-angle glaucoma (POAG) is a serious form of eye diseases leading to blindness and disability. Glaucoma ...
Background: Folate cycle enzymes regulate key reactions in folate-mediated single-carbon metabolism. The folate cycle disturbances may be associated ...
Relevance. Glutamate-cysteine ligase (GCL) is the first enzyme of the glutathione cycle, intra- and extracellular antioxidant, whose impaired metabolism ...
Background: Breast cancer (BC) is a malignant breast tumor, which occupies a leading place both in the structure of ...
Background: Fetal growth restriction is a common complication of pregnancy that has been associated with a variety ...
Background: Fetal growth retardation (FGR) is one of the most common pregnancy complications that can adversely affect the short- ...
Background: Glycogen synthase 2 (GYS2) catalyzes a key step in glycogenesis in the liver. Loss-of-function mutations in the GYS2 ...
Background: Schizophrenia is a multifactorial and clinically polymorphic disease with a significant hereditary component. The study of the influence ...
ASSOCIATION OF VEGFA, FACTOR V AND PROTHROMBIN GENE POLYMORPHISMS WITH EARLY PREGNANCY LOSS
Background: Many studies conducted to assess the associations between the gene polymorphisms of factor V, prothrombin, and vascular endothelial ...
RELATIONSHIP BETWEEN POLYMORPHISM RS1546155 OF THE GGT7 GENE AND THE RISK OF ISCHEMIC STROKE
Background: Since oxidative stress plays a role in the pathogenesis of ischemic stroke (IS), it is important ...
Background: The problem of chronic polyposis rhinosinusitis is one of the most common diseases in modern otorhinolaryngology with an ...
Background: Studying the genetic foundations of primary open-angle glaucoma (POAG) is an urgent task due to the fact ...
Background: Host-pathogenic interaction is a necessary but not sufficient precondition for the development of the disease. The immune response ...
POLYMORPHIC LOCI OF AC026703.1 AND HFE GENES ARE ASSOCIATED WITH SEVERE HYPERTENSION
 Background: Hypertension (HT) is characterized by high blood pressure (BP) and is one of the most common diseases in ...
GENETIC MARKERS OF KNEE OSTEOARTHRITIS IN WOMEN OF THE CENTRAL CHERNOZEM REGION OF RUSSIA
Background: Knee osteoarthritis (KO) is a multifactorial disease. Among the many risk factors for the disease, the role of ...
Background: Mitochondria play a major role in providing cells with energy, but at the same time they are a ...
Background: One of the important tasks is to study the molecular genetic basis of gastric and duodenal ulcer. This ...
Background: The superoxide dismutase 2 (SOD2) gene encodes a mitochondrial enzyme whose main function is to convert superoxide ...
MOLECULAR AND GENETIC CHARACTERISTICS OF PATIENTS WITH HYPERPLASIA AND ENDOMETRIC POLYPS
Background. Hyperplastic processes of the endometrium (GGE) are among the most frequent gynecological diseases, leading to a loss of ...
Background: Placental insufficiency (PI) is a key feature of pregnancies with fetal growth restriction (FGR). FGR is defined ...
Background: The dysfunction of vascular endothelial growth factor A (VEGFA) is one of the leading factors of macro- and ...
MOLECULAR GENETIC DETERMINANTS OF PRE-ECLAMPSIA
Background: Pre-eclampsia (PE) is still one of the most severe complications of pregnancy. Molecular genetic factors are involved in ...
Background: When studying associations of candidate genes with multifactorial diseases, the formation of samples for research is important. One ...
RS34845949 POLYMORPHISM OF THE SASH1 GENE IS ASSOCIATED WITH THE RISK OF PREECLAMPSIA
 Background: Preeclampsia (PE) is a multisystem pathological condition that occurs in the second half of pregnancy (after the ...
GENETIC DETERMINANTS OF SEX HORMONE LEVELS IN ENDOMETRIOSIS PATIENTS
 Background: Endometriosis is a chronic hormone-dependent inflammatory disease determined by the presence of foci of the endometrial ...
Background: Eczema is a multifactorial disease. Its development is determined by the polygenic basis and the action of inciting ...
Background: The level of IL-1β in blood plasma is determined not only by pro-inflammatory stimuli, but also by ...
Background: Pregnancy complications have a high prevalence and important medical and social implications. Genetic factors are involved ...
MODERN GENOMICS IN STUDYING THE PROBLEMS OF HUMAN ADAPTATION TO CLIMATE IN NORTH SIBERIA
Background: Indigenous people of north Siberia live in some of the harshest natural conditions on Earth, experiencing prolonged ...
Background: In the genetic and epidemiological study of multifactorial signs (diseases), an important task is to assess the genetic ...
Background: It is well known that gene polymorphisms of antioxidant defense enzymes contribute to the ischemic stroke (IS) predisposition and ...
Background: The study of the involvement of polymorphisms of candidate genes of the biotransformation system of xenobiotics in the ...
Background: Genome-wide association studies (GWAS) are a type of genetic research whose purpose is to analyze the associations ...
Background: Atherosclerosis obliterans (AO) and diabetic angiopathy (DA) are known to be peripheral artery diseases (PAD) of multifactorial origin, ...
SEX-SPECIFIC FEATURES OF INTERLOCUS INTERACTIONS DETERMINING SUSCEPTIBILITY TO HYPERTENSION
 Background: Hypertension (HT) belongs to a group of widespread diseases in both men and women, but at the ...
Background: The most common complications of pregnancy associated with metabolic and hemodynamic disorders in the mother-placenta-fetus system are ...
Background: Coronary heart disease (CHD) is a common disease with a high mortality rate in Russia, so the ...
Background: One of the most common diseases of the female population is breast cancer (BC), which is ...
Background: Phosphatidylethanolamine N-methyltransferase (PEMT) is the enzyme of lipid metabolism that catalyzes the conversion of phosphatidylethanolamine to phosphatidylcholine ...
Background: Eczema is a common chronic disease characterized by inflammation of the skin. The aim of the study: ...
Background: Chronic rhinosinusitis (CRS) is a common disease of the nose and paranasal sinuses with a protracted, relapsing ...
Background: It is known that the development of coronary heart disease (CHD) as a polygenic multifactorial pathology is ...
Background: Today, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery disease (CAD). Despite all technical ...
Background: According to statistics, the first place among the causes of death worldwide is occupied by cardiovascular diseases ...
Background: Positioned as one of the central members in cellular antioxidant defense, glutathione reductase (GSR) determines the oxidative status ...
Cardiovascular diseases are the leading cause of death and disability in Russia and in the world, and hypertension ...
GENETIC INTERRELATIONS OF RUSSIAN AND UKRAINIAN POPULATIONS OF BELGOROD REGION
This article presents the results of the study of genetic relationship between the indigenous Russian and Ukrainian population of Belgorod ...
Background: Chronic arterial hypertension and preeclampsia are multifactorial pathologies, in the development of which many groups of genes are ...
NOS3 GENE POLYMORPHISM VARIANTS AND MAIN CHARACTERISTICS OF HEART RATE VARIABILITY IN NORTHERNERS
Background: Heart rate variability as a demonstration of autonomic nervous system function reflects human health and well-being. By ...
MOLECULAR-GENETIC DETERMINANTS OF INFERTILITY IN GENITAL ENDOMETRYOSIS
Background: Genital endometriosis is an urgent problem of modern medicine. It is one of the hard-to-explain diseases and is ...
Background: Endometriosis is a chronic inflammatory, dyshormonal disease. Genetic factors play an important role in its development. ...
CONTRIBUTION OF RS11927381 POLYMORPHISM OF THE IGF2BP2 GENE TO THE PATHOGENESIS OF TYPE 2 DIABETES
Background: Pancreatic beta-cell dysfunction, along with the insulin resistance of peripheral tissues, is a key element in the ...
Background: HPV infection leads to an imbalance of pro- and anti-inflammatory cytokines, which contributes to the long-term persistence of ...
Background: Preeclampsia (PE) is one of the most serious pregnancy complications and is the leading cause of maternal and ...
Background: Coronary heart disease (CHD) is the leading pathology among all cardiovascular diseases. Elderly patients with concomitant diseases represent ...
Background: Social orphans have a variety of behavioural and intellectual disorders. A number of specific polymorphisms in ...
