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Research Results in Biomedicine

Volume 7, Issue №1, 2021 PDF
Genetics

First molecular cytogenetic characterization of the MMT 060562 murine breast cancer cell line

Background: Murine cell lines are working horses applied as model systems in multiple research studies in many laboratories. Nonetheless, most of them are not well characterized at the ...

Bioinformatic tools and internet resources for functional annotation of polymorphic loci detected by genome wide association studies of multifactorial diseases (review)
 

Background: Genome-wide association studies (GWAS) are a type of genetic research whose purpose is to analyze the associations between genomic variants and phenotypic traits in a population. Over ...

Associations of rs2305948 and rs1870377 polymorphic variants of the vascular endothelial growth factor receptor type 2 (KDR) gene with the risk of coronary heart disease
 

Background: According to statistics, the first place among the causes of death worldwide is occupied by cardiovascular diseases (CVD), of which a large proportion are cases of coronary ...

rs34845949 polymorphism of the SASH1 gene is associated with the risk of preeclampsia
 

Background: Preeclampsia (PE) is a multisystem pathological condition that occurs in the second half of pregnancy (after the 20th week), characterized by arterial hypertension in combination with proteinuria ...

Features of gene control of blood pressure in patients with hypertensive disorders during pregnancy
 

Background: Chronic arterial hypertension and preeclampsia are multifactorial pathologies, in the development of which many groups of genes are involved in combination with negative environmental influence. The aim ...
Pharmacology

Pharmacological effect of indolicidin-like peptides on vasoactive substances content in experimental periodontitis

Background: The anti-inflammatory effect of indolicidin-like peptides, which have a wide range of antimicrobial effects, has been already reported in several studies. The inflammation of the periodontium is ...
Medicine (miscellaneous)

Development of gerontology and geriatrics in Mongolia

Background: The population of Mongolia in 2020 is estimated at 3,305,625 thousand people, thus it has increased by 25.3% since 2000, by about 5.6% per year. The ...

Mismatch of daily biorhythms of blood pressure and heart rate in elderly patients with myocardial infarction

Background: Myocardial infarction in the elderly population of our country is a leading cause of disability and mortality. In the development of myocardial infarction, an important role ...

Induced preterm birth: evaluation of oxidative status, matrix metalloproteinases and their tissue inhibitors in amniotic fluid

Background: Hypoxic brain injury is the most common pathology in newborns. New criteria of viability and progress of perinatal technologies results in high neurological morbidity of surviving very ...

Anxiety-depressive and cognitive impairments in elderly patients with age-related macular degeneration and cataracts

Background: The continuing change in the demographic structure of society in different states is accompanied by a restless increase not only in the proportion of the elderly ...