Research Results in Biomedicine
Volume 5, Issue №2, 2019
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Genetics
An update on small supernumerary marker chromosomes (sSMC)
Background: Small supernumerary marker chromosomes (sSMCs) are a clinical problem in prenatal and postnatal diagnostic cases. They include few well-defined clinical syndromes, like cat eye syndrome or Emanuel ...
Epidеmiоlоgy оf hеrеditаry skin disеаsеs in thе pоpulаtiоn оf thе Rоstоv region
Background: Hereditary skin diseases (HSD) – a group of diseases, mediated by mutations in the genes, responsible for the formation and function of the skin. Literature data on the ...
Analysis of polymorphic gene loci of antioxidant protection enzymes in three ethnic groups of the Republic of Bashkortostan
Background: The ideal dose of drugs varies widely among patients, mainly due to genetic factors. Introduction to clinical practice of pharmacogenetic testing in a certain region should be preceded ...
Analysis of the association between C936T VEGFA gene polymorphism and diabetic foot syndrome in the Ukrainian population
Background: The dysfunction of vascular endothelial growth factor A (VEGFA) is one of the leading factors of macro- and microangiopathy development in diabetic foot syndrome (DFS) patients. Recently, a ...
Pharmacology
Development of the composition, production technology, biological studies of medicinal syrup with ethylmethylhydroxypyridine succinate for the prevention and treatment of hypoxic conditions
Background: Both the dosage form and the complex of auxiliary substances are important pharmaceutical factors determining the final pharmacological effect. It is important to carefully select different groups of ...
Correction of ischemic and reperfusion damage in the retina by using imidazoline receptors agonists of types I, II in rats
Background: The authors note that special literature does not make mention of drugs for targeted, specific correction of retinal ischemia. That is why the study of the possibilities of ...
Practical aspects of the analysis of pharmaceutical substances by the indicator «bacterial endotoxins»
Background: Safety is one of the basic medicine requirements. «Bacterial endotoxins» is the most important safety indicator of parenteral drug products, ensuring their proper quality. The use of the ...
Medicine (miscellaneous)
Factors of social disadaptation of patients with schizophrenia and approaches to psychosocial therapy and rehabilitation (review)
Background: Schizophrenia tends to affect people at the age when they are most active socially and professionally. Therefore, the earliest possible start ...
Forecasting a uterine scar failure through the assessment of mast cells
Background: The formation of a solid uterine scar depends on how adequate reparative process is in the uterine wall. The majority of researchers observe a decrease in the ...
Chronic osteomyelitis of the jaw as a manifestation of oncohematological pathology in old age
Oncohematological diseases often debut with various inflammatory processes localized in different regions, including the maxillofacial region. Myelodysplastic syndrome in a 77-year-old patient with long-lasting hemorrhaging on the skin ...
