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Research Results in Biomedicine

Volume 7, Issue №2, 2021 PDF
Genetics

Association of VEGFA, factor V and prothrombin gene polymorphisms with early pregnancy loss

Background: Many studies conducted to assess the associations between the gene polymorphisms of factor V, prothrombin, and vascular endothelial growth factor gene A and recurrent early pregnancy loss ...

Association of polymorphism of genes STAT3, IL10 and IL12B with a viral load in women with human papillomavirus

Background: HPV infection leads to an imbalance of pro- and anti-inflammatory cytokines, which contributes to the long-term persistence of the virus in infected cells. The aim of the ...

Polymorphism of genes associated with the age at menarche and the risk of complications of pregnancy in women in the Central Black Earth Region of Russia
 

Background: The most common complications of pregnancy associated with metabolic and hemodynamic disorders in the mother-placenta-fetus system are placental insufficiency and preeclampsia. Preeclampsia is one of the leading ...

Influence of some risk factors and rs1799930 polymorphism of the NAT2-590 G>A gene on the development of chronic pancreatitis
 

Background: Genetic and environmental factors are involved in the development of chronic pancreatitis. The aim of the study: To determine the influence of some risk factors and polymorphism ...
Pharmacology

Study on the antioxidant capacity of Hibiscus rosa-sinensis decoction in vivo in Mus musculus var. albino
 

Background: In humans, many diseases including cancer are associated with the accumulation of free radicals. Antioxidants can scavenge free radicals and minimize those impacts. Therefore, the antioxidants are ...
Medicine (miscellaneous)

Estrogens and uterine fibroids: an integrated view
 

Background: Uterine fibroids or uterine leiomyomata (UL) are common benign tumors of the uterine myometrium affecting a significant proportion of women at reproductive age. UL is a disease ...

Influence of clinical and biological variants of premature aging on cognitive functionality
 

Background: Currently, the development of gerontology as a related medical and biological discipline follows the path of concepts; there are three of them in classical gerontology: frailty, intrinsic ...

Changes in the blood complement system in the development of diabetic retinopathy in the elderly
 

Background: In the elderly, diabetic retinopathy causes a significant deterioration in the functional activity and quality of life of patients, but the individual mechanisms of its development and, ...

Vaccination against human papillomavirus is a fundamental factor in the prevention of cervical cancer (review)
 

Background: Infection of the sexually active population with the human papillomavirus is one of the major health problems worldwide, due to the risk of malignant neoplasms of the ...

Cognitive dysfunction in elderly patients with chronic systolic heart failure
 

Background: Nowadays, we can see a rapid increase in systolic chronic heart failure patients. Cognitive decline is one of the most frequent and important among geriatric syndromes. Cognitive ...

Effects of psychopharmacotherapy and patients’ adherence: interdependence within the biopsychosocial paradigm

Background: The expected effects of psychopharmacology in the clinic are mediated by changes in dopamine and serotonin neurotransmission that can determine impaired motivational processes in patients. The aim ...