16+

Research Results in Biomedicine

Volume 5, Issue №3, 2019 PDF
Genetics

The applicability of interphase chromosome-specific multicolor banding (ICS-MCB) for studying neurodevelopmental and neurodegenerative disorders

Background: Interphase chromosome-specific multicolor banding (ICS-MCB) has been developed for studying whole chromosomes in interphase nuclei at any stage of the cell cycle at molecular resolution. Previously, important biomedical ...

Familial translocation t(5;11)(q32;q23) resulting in Jacobsen syndrome and distal trisomy 5q31 in a female patient

Background: Jacobsen syndrome is a rare contiguous gene disorder caused by partial deletion of the distal part of the long arm of chromosome 11 (prevalence 1/100,000 live births). Most ...

A clinical case of Proteus syndrome in an early age child

Despite the undoubted progress of medical science around the world, recently, there has been a tendency of an increase in the frequency of congenital malformations and hereditary diseases in ...

Search for binding sites for micro RNA in cis-regulatory sequences and in SNP in the lipid, carbohydrate metabolism, oxidative and anti-inflammatory homeostasis genes

Background: Polymorphisms and disruption of the expression profile of miRNA genes are associated with systemic diseases (autoimmune and cardiovascular diseases). The aim of the study: To study the localization ...
Pharmacology

The study of adaptogenic activity and toxicological safety of the Nigella damascena seed fatty oil extract

Background: Nigella damascena L. is a plant, extracts from which are characterized by a multicomponent composition of biologically active substances, which have an extensive spectrum of pharmacological properties. In ...

The study of neurodynamic disturbances in rats with cranial injury

Background: Domestic and occupational injuries, including traumatic brain injury (TBI), are diseases that are a major public health problem in all industrialized countries and result in incapacitation, as well ...

Determination of the antioxidant activity of the infusion of common sorrel herba in vitro

Background: Common sorrel (Rumex acetosa L.), a plant from the buckwheat family, is promising for introduction into medicine. Phytochemical studies of common sorrel herba showed that the raw material ...
Medicine (miscellaneous)

IL-2, IL-10, IL-12 and IL-23 mRNA expression in the decidual tissue in patients with missed and spontaneous abortions in early pregnancy

Background: Miscarriages are one of the most common complications of the first term of pregnancy. The rate of early miscarriages is about 15% of all diagnosed cases. Meanwhile, immune ...

Age-related changes in microcirculation: the role of regular physical activity

Background: The role of age-related changes in adaptive responses of the circulatory system is well known. The most important part of the cardiovascular system is the microvascular bed, where ...

Long-term effects and development of psychosexuality in people – victims of sexual abuse

Background: Numerous studies show the disorganizing effect of sexual abuse in childhood and adolescence in all areas of mental activity. Episodes of sexual abuse remain in the memory ...