Research Results in Biomedicine
Volume 10, Issue №2, 2024
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Genetics
HSPD1 gene polymorphism is associated with an increased risk of ischemic stroke in smokers
Background: Ischemic stroke (IS) is a leading cause of death and disability worldwide. Since the influence of vascular stressors prompts cross-reactivity with microbial and human HSPD1 (HSP60), which ...
Search for molecular markers of joint hypermobility
Background: Joint hypermobility (JH) is a condition that can be either benign or accompanied by pain and early development of osteoarthritis. For early verification of the risk of ...
Polymorphism in the matrix metallopeptidase genes is associated with coronary artery disease risk with concomitant metabolic syndrome
Background: Metabolic syndrome (MS) and its components are the reasons of the development and progression of cardiovascular diseases. Nowadays, the association between coronary artery disease and MS ...
Genetic variant rs11568818 of matrix metalloproteinase MMP7 associated with newborn weight in pregnant women with fetal growth restriction
Background: Fetal growth restriction is a common complication of pregnancy that has been associated with a variety of adverse perinatal outcomes. The condition carries significant risks of ...
Pharmacology
Potential protective effect of alpha lipoic acid against testicular oxidative stress and altered gene expression induced by gentamicin treatment
Background: Gentamicin induces testicular damage in association with oxidative stress explained by different mechanisms, including gene expression suppression of some antioxidant enzymes. The aim of the study: ...
In vitro activity of the novel antimicrobial peptide WR-286 in combination with vancomycin against methicillin-resistant
Staphylococcus aureus
Background: Multidrug resistance bacteria are a serious problem for health specialists and all the people in the world. The main reasons for this problem are the misuse ...
Mechanisms of biological effectiveness of ionic forms of metals of variable valence in respiratory medicine
Background: The task to develop new drugs containing metals of variable valence requires systematization of our knowledge, experimental and clinical studies. The aim of the study: To investigate ...
Medicine (miscellaneous)
The use of psychotropic drugs in oncological diseases (review)
Background: It is estimated that at least 25-30% of cancer patients experience mental disorders. Due to the high prevalence of these disorders among this patient population, psychotropic drugs have ...
Differential expression of CYP19A1 and lncRNA-CTBP1-AS in the granulosa cells of women with polycystic ovary syndrome
Background: Hyperandrogenism is the basic indicator of polycystic ovarian syndrome (PCOS) and a key factor in its pathological processes. Patients with PCOS have higher testosterone levels along with ...
Relationship between the cognitive status of the long-living adults of the Central Federal District of the Russian Federation and socioeconomic factors: analysis of associations
Background: In recent years, an increase in the number of long-living adults has been a dominant demographic trend in Russia. This population group is highly susceptible to cognitive ...
