Research Results in Biomedicine
Volume 5, Issue №3, 2019
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Genetics
The applicability of interphase chromosome-specific multicolor banding (ICS-MCB) for studying neurodevelopmental and neurodegenerative disorders
Background: Interphase chromosome-specific multicolor banding (ICS-MCB) has been developed for studying whole chromosomes in interphase nuclei at any stage of the cell cycle at molecular resolution. Previously, important biomedical ...
Familial translocation t(5;11)(q32;q23) resulting in Jacobsen syndrome and distal trisomy 5q31 in a female patient
Background: Jacobsen syndrome is a rare contiguous gene disorder caused by partial deletion of the distal part of the long arm of chromosome 11 (prevalence 1/100,000 live births). Most ...
A clinical case of Proteus syndrome in an early age child
Despite the undoubted progress of medical science around the world, recently, there has been a tendency of an increase in the frequency of congenital malformations and hereditary diseases in ...
Search for binding sites for micro RNA in cis-regulatory sequences and in SNP in the lipid, carbohydrate metabolism, oxidative and anti-inflammatory homeostasis genes
Background: Polymorphisms and disruption of the expression profile of miRNA genes are associated with systemic diseases (autoimmune and cardiovascular diseases). The aim of the study: To study the localization of miRNA ...
Pharmacology
The study of adaptogenic activity and toxicological safety of the Nigella damascena seed fatty oil extract
Background: Nigella damascena L. is a plant, extracts from which are characterized by a multicomponent composition of biologically active substances, which have an extensive spectrum of pharmacological properties. In this ...
The study of neurodynamic disturbances in rats with cranial injury
Background: Domestic and occupational injuries, including traumatic brain injury (TBI), are diseases that are a major public health problem in all industrialized countries and result in incapacitation, as well ...
Determination of the antioxidant activity of the infusion of common sorrel herba in vitro
Background: Common sorrel (Rumex acetosa L.), a plant from the buckwheat family, is promising for introduction into medicine. Phytochemical studies of common sorrel herba showed that the raw material ...
Medicine (miscellaneous)
IL-2, IL-10, IL-12 and IL-23 mRNA expression in the decidual tissue in patients with missed and spontaneous abortions in early pregnancy
Background: Miscarriages are one of the most common complications of the first term of pregnancy. The rate of early miscarriages is about 15% of all diagnosed cases. Meanwhile, immune ...
Age-related changes in microcirculation: the role of regular physical activity
Background: The role of age-related changes in adaptive responses of the circulatory system is well known. The most important part of the cardiovascular system is the microvascular bed, where ...
Long-term effects and development of psychosexuality in people – victims of sexual abuse
Background: Numerous studies show the disorganizing effect of sexual abuse in childhood and adolescence in all areas of mental activity. Episodes of sexual abuse remain in the memory ...
