Research Results in Biomedicine
Volume 5, Issue №4, 2019
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Genetics
The role of interaction of polymorphic loci of the FLG gene in the development of chronic true eczema in women
Background: Eczema is a multifactorial disease. Its development is determined by the polygenic basis and the action of inciting events of exogenous and endogenous nature. The aim of the ...
Association of the mitochondrial DNA haplogroup H1 variants with the risk of acute cardiovascular events
Background: Mitochondria play a major role in providing cells with energy, but at the same time they are a source of free radicals that increase oxidative stress. It is ...
Effect of IL10 (rs1800872) and CXCL10 (rs4386624, rs4256246) genes polymorphism in the development of viral and bacterial infectious diseases
Background: Host-pathogenic interaction is a necessary but not sufficient precondition for the development of the disease. The immune response to the introduction of pathogen is largely controlled by genetic ...
Cytogenetic analysis in the era of high-resolution molecular-cytogenetic methods: the potential of «reverse» karyotyping
Background: The introduction of high-resolution molecular-cytogenetic methods to clinical practice has allowed to reveal complex “cryptic” structural chromosomal rearrangements, which could not be detected by a standard cytogenetic analysis. ...
Population analysis of the polymorphic marker rs1002149 of the glutathione reductase gene in residents of the Republic of Bashkortostan and Abkhazia
Background: Positioned as one of the central members in cellular antioxidant defense, glutathione reductase (GSR) determines the oxidative status of a cell. The level of its activity changes in ...
Pharmacology
A comparative analysis of physicians’ basic knowledge with different work experience in the treatment of community-acquired pneumonia. Project «КnoCAP», II phase (2017-2019)
Background: Community-acquired pneumonia (CAP) is an acute infectious inflammatory disease more often of bacterial etiology that occurs in outside hospital settings. This pathology is an important medical and ...
Feasibility study of the eye drops composition with vitamins for the treatment of allergic conjunctivitis
Background: Today, quite a lot of people suffer from allergic conjunctivitis, despite the sufficient market of monocomponent medicines, there is a shortage of combined medicines based on modern substances ...
Medicine (miscellaneous)
Resilience in gerontology and geriatrics (review)
Background: Currently, due to the increase in life expectancy and the increasing need for the development of specialized types of medical, social, psychological, and spiritual services to people ...
Risk factors of suicidal behavior of minors (based on the materials of postmortem complex forensic psychological and psychiatric examinations)
Background: Numerous studies show that the younger generation has been at high risk for suicidogenesis in recent decades. In various countries of the world, juvenile suicidal behavior has an ...
Individual resilience in the study of longevity factors
Background: In recent years, the issues of longevity and its determining factors have been actively discussed. Among studies of this kind, the study of population longevity, in other ...
Molecular genetic determinants of pre-eclampsia
Background: Pre-eclampsia (PE) is still one of the most severe complications of pregnancy. Molecular genetic factors are involved in the formation of PE. The aim of the study: To study ...
Sarcopenia as a predictor of decreased socialization and quality of life in older patients
Background: The preservation of socialization of older patients is becoming an important problem. A real understanding of the socialization of patients of older age groups requires ...
