Genetics
MOLECULAR AND GENETIC CHARACTERISTICS OF PATIENTS WITH HYPERPLASIA AND ENDOMETRIC POLYPS
Volume 4, Issue №2, 2018
Background. Hyperplastic processes of the endometrium (GGE) are among the most frequent gynecological diseases, leading to a loss of reproductive function and a decrease in the quality of life ...
POLYMORPHISM OF IL10, CTLA4 GENES AND PREDISPOSITION TO RHEUMATOID ARTHRITIS
Volume 4, Issue №2, 2018
Background. Rheumatoid arthritis (RA) is a systemic autoimmune disease, accompanied by chronic inflammation of the joints synovial membrane and a wide spectrum of extra-articular manifestations. Today, the problem of ...
BIOMARKERS FOR CHILDHOOD NONMALIGNANT BRAIN DISEASES ASSOCAITED WITH CHROMOSOME INSTABILITY
Volume 4, Issue №2, 2018
Background. Over the past ten years, there has been provided a sufficient amount of data demonstrating that chromosome instability is not limited to being a molecular and cellular mechanism ...
THE ROLE OF POLYMORPHISMS OF GLUTAMATE-CYSTEINE LIGASE IN TYPE 2 DIABETES MELLITUS SUSCEPTIBILITY IN KURSK POPULATION
Volume 4, Issue №1, 2018
Relevance. Glutamate-cysteine ligase (GCL) is the first enzyme of the glutathione cycle, intra- and extracellular antioxidant, whose impaired metabolism plays an important role in type 2 diabetes (T2D) pathogenesis. ...
THE INVOLVEMENT OF GENES OF MATRIX METALLOPROTEINASES IN THE DEVELOPMENT OF ARTEIAL HYPERTENSION AND ITS COMPLICATION (REVIEW)
Volume 4, Issue №1, 2018
Cardiovascular diseases are the leading cause of death and disability in Russia and in the world, and hypertension is considered to be an independent predisposing factor in such ...
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