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Research Results in Biomedicine

Volume 4, Issue №4, 2018
Genetics

Association of the ITGB3 gene T1565C polymorphism with the development of atherosclerosis and in-stent restenosis in patients with stable coronary artery disease

Background: Today, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery disease (CAD). Despite all technical advances in stent designs and techniques, in-stent restenosis (ISR) remains ...

Population genetic characteristics and genetic epidemiological research of candidate genes associations with multifactorial diseases

Background: When studying associations of candidate genes with multifactorial diseases, the formation of samples for research is important. One of the factors that should be considered in the formation ...
Pharmacology, clinical pharmacology

Perspective materials for drug delivery in the ophthalmic dosage form: a short review of polymers for electrospinning

Background: The traditional ophthalmological dosage forms have a low bioavailability, a rapid precorneal clearance and a low corneal permeability. The gelling system or system with a prolonged action (prolonged ...

Pharmacological correction of metabolic disturbances in experimental acute pancreatitis on the background of chronic alcohol intoxication

Background: Acute pancreatitis ranks third among all acute surgical diseases of the abdominal cavity and is one of the important unresolved problems in emergency surgery. The aim of the ...

Development of the composition and analysis of suppositories of antihemorrhoidal action

Background: The study is devoted to the development of composition and assessment of the quality of two-layered suppositories with an oil extract of rowanberries (
Clinical Medicine

Effects of ked peptide on connexin and sirutin expression in atherosclerosis and restinosis in elderly people

Background: Despite the wide range of application of the KED peptide, the molecular mechanisms of its action are still not fully ...

The value of determining concentrations of calcidiol and vascular endothelial growth factor to predict non-developing pregnancy

Background: Non-developing pregnancy is one of the most difficult medical and social problems of modern obstetrics and gynecology, which has no tendency to decrease. Previously occurred non-developing pregnancy is ...

Nonpsychotic mental disorders in patients with benign hypersplasia of the prostate gland (clinic and therapy)

Background: Benign prostatic hyperplasia (BPH) is the most common disease of the genitourinary system in elderly men. It hampers social functioning and reduces the quality of life. The aim ...