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Pharmacology

Morphofunctional changes in the retina when modeling the glaucoma process in rats
 

Volume 6, Issue №4, 2020
Background: Neuroprotective approaches are considered to be the most promising among existing modern directions in the development of antiglaucomatous drugs. The aim of the study: The detection of ...

Investigation of cerebroprotective properties of the drug «Mexidol» on the model of pneumococcal bacterial meningitis in experimental conditions

Volume 6, Issue №3, 2020
Background: Pneumococcal meningitis is a severe infectious disease, which is characterized by high mortality and frequent development of residual neurological damage. Effective cerebroprotection can improve the outcome of ...

Exhaled nitric oxide as a predictor of the effectiveness of basic therapy for bronchial asthma in children
 

Volume 6, Issue №2, 2020
Background: The article discusses the predictive ability of monitoring nitric oxide in exhaled air relative to the level of control and the likelihood of developing exacerbations of bronchial ...

Modern possibilities of using the release-active drug Tenoten for Children in the clinical practice of autonomic disorders in children
 

Volume 6, Issue №2, 2020
Background: Among the pathological conditions found in children and adolescents, vegetative disorders occupy one of the leading places. The development of autonomic dysfunction is due to an imbalance ...

A study of neuroprotective properties of the MGLUR4 receptor agonist – ZC64-0001 in comparison with Mexidol
 

Volume 6, Issue №2, 2020
Background: One of the most common neurodegenerative diseases is Parkinson's disease, which is based on the degeneration of dopaminergic neurons of the substantia nigra. The modern treatment for Parkinson's ...

Feasibility study of the eye drops composition with vitamins for the treatment of allergic conjunctivitis

Volume 5, Issue №4, 2019
Background: Today, quite a lot of people suffer from allergic conjunctivitis, despite the sufficient market of monocomponent medicines, there is a shortage of combined medicines based on modern substances ...

The study of neurodynamic disturbances in rats with cranial injury

Volume 5, Issue №3, 2019
Background: Domestic and occupational injuries, including traumatic brain injury (TBI), are diseases that are a major public health problem in all industrialized countries and result in incapacitation, as well ...

Determination of the antioxidant activity of the infusion of common sorrel herba in vitro

Volume 5, Issue №3, 2019
Background: Common sorrel (Rumex acetosa L.), a plant from the buckwheat family, is promising for introduction into medicine. Phytochemical studies of common sorrel herba showed that the raw material ...

The study of adaptogenic activity and toxicological safety of the Nigella damascena seed fatty oil extract

Volume 5, Issue №3, 2019
Background: Nigella damascena L. is a plant, extracts from which are characterized by a multicomponent composition of biologically active substances, which have an extensive spectrum of pharmacological properties. In this ...

Practical aspects of the analysis of pharmaceutical substances by the indicator «bacterial endotoxins»

Volume 5, Issue №2, 2019
Background: Safety is one of the basic medicine requirements. «Bacterial endotoxins» is the most important safety indicator of parenteral drug products, ensuring their proper quality. The use of the ...

Correction of ischemic and reperfusion damage in the retina by using imidazoline receptors agonists of types I, II in rats

Volume 5, Issue №2, 2019
Background: The authors note that special literature does not make mention of drugs for targeted, specific correction of retinal ischemia. That is why the study of the possibilities of ...

Pharmacological correction of immune and metabolic disorders in acute biliary pancreatitis of varying severity

Volume 5, Issue №1, 2019
Background: The incidence of acute pancreatitis is up to 40 cases per 100,000 adult population per year, including about 10-15% of patients with severe forms of this disease, ...

Comparative evaluation of the effectiveness of DMAE derivative 7-16, carbamilated darbepoetin and substance C7070 in correction of hypertensive neuroretinopathy in rats

Volume 5, Issue №1, 2019
Background: Increasing the effectiveness of drug therapy for hyperintensive neuroretinopathy is one of the important tasks of pharmacology and ophthalmology. The aim of the study: To assess the effectiveness of DMAE ...

Pharmacological correction of metabolic disturbances in experimental acute pancreatitis on the background of chronic alcohol intoxication

Volume 4, Issue №4, 2018
Background: Acute pancreatitis ranks third among all acute surgical diseases of the abdominal cavity and is one of the important unresolved problems in emergency surgery. The aim of the ...
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