Background: This article reviews the pharmacological characteristics of developed dosage forms for intranasal administration. The influence of the type of dosage form on the efficacy of the drug ...
Wound healing effect of organometallic zinc complex in the rat model of planar skin wound
Volume 8, Issue №1, 2022
Background: The complex and dynamic process of wound healing involves the stages of inflammation, proliferation and maturation of the connective tissue of the scar. Zinc, as an essential trace ...
Effect of sodium-glucose cotransporter type 2 inhibitors on the dynamics of functional and structural disorders in the simulation of post-contrast acute kidney injury
Volume 8, Issue №1, 2022
Background: Sodium-glucose cotransporter type 2 inhibitors have significantly changed nephroprotection strategies in various categories of patients over the past few years. However, there is no data on their ...
Pharmacological efficiency of combined eye drug films based on Levofloxacin and Dexpanthenol, and also Dexamethazone and Dexpanthenol in the treatment of infected corneal injury
Volume 7, Issue №4, 2021
Background: When treating infected corneal burns, some patients are not able to comply with the schedule of frequent instillations of drugs, which entails a persistent irreversible decrease in visual ...
Background: Laurel noble – Laurus nobilis L., a plant whose leaves are widely used in cooking and are used in folk medicine. L. nobilis L. leaves contain more than ...
Background: Currently, there are no drugs for the specific treatment of hypertensive retinal changes. The main therapy is for the treatment of a systemic disease – hypertensive disease. Therefore, the ...
Study on the antioxidant capacity of Hibiscus rosa-sinensis decoction in vivo in Mus musculus var. albino
Volume 7, Issue №2, 2021
Background: In humans, many diseases including cancer are associated with the accumulation of free radicals. Antioxidants can scavenge free radicals and minimize those impacts. Therefore, the antioxidants are ...
Background: The anti-inflammatory effect of indolicidin-like peptides, which have a wide range of antimicrobial effects, has been already reported in several studies. The inflammation of the periodontium is ...
Effects of first-line anti-TB drugs on the level of toxic plasma phospholipids
Volume 6, Issue №4, 2020
Background: The target of any toxic effect of anti-tuberculosis chemotherapy is primarily the cell. Changes in the structure and functions of cells affect the lipid composition of their membranes ...
Morphofunctional changes in the retina when modeling the glaucoma process in rats
Volume 6, Issue №4, 2020
Background: Neuroprotective approaches are considered to be the most promising among existing modern directions in the development of antiglaucomatous drugs. The aim of the study: The detection of ...
Background: Pneumococcal meningitis is a severe infectious disease, which is characterized by high mortality and frequent development of residual neurological damage. Effective cerebroprotection can improve the outcome of ...
The final results of the ASSA-II study: the knowledge of therapeutic doctors on the subject of bronchial asthma
Volume 6, Issue №3, 2020
Background: Bronchial asthma (BA) is one of the leading and socially significant diseases of the respiratory system. In recent years, the proportion of this disease has been steadily ...
Exhaled nitric oxide as a predictor of the effectiveness of basic therapy for bronchial asthma in children
Volume 6, Issue №2, 2020
Background: The article discusses the predictive ability of monitoring nitric oxide in exhaled air relative to the level of control and the likelihood of developing exacerbations of bronchial ...
Modern possibilities of using the release-active drug Tenoten for Children in the clinical practice of autonomic disorders in children
Volume 6, Issue №2, 2020
Background: Among the pathological conditions found in children and adolescents, vegetative disorders occupy one of the leading places. The development of autonomic dysfunction is due to an imbalance ...
A study of neuroprotective properties of the MGLUR4 receptor agonist – ZC64-0001 in comparison with Mexidol
Volume 6, Issue №2, 2020
Background: One of the most common neurodegenerative diseases is Parkinson's disease, which is based on the degeneration of dopaminergic neurons of the substantia nigra. The modern treatment for Parkinson's ...
Pharmacological effects of the combined administration of a small dose of Acetylsalicylic acid and methyldopa in ADMA-like preeclampsia
Volume 6, Issue №1, 2020
Background: Hypertensive disorders, in particular preeclampsia, which accounts for 2 to 8% of the total number of pregnancies in the world, are one of the leading causes of ...
Comprehensive assessment of using micronised purified flavonoid fraction in the correction of disorders associated with ADMA-like preeclampsia in experiment
Volume 6, Issue №1, 2020
Background: About 10% of pregnancies in the world are accompanied by hypertensive disorders, while from 2 to 8% are preeclampsia. One of the components of the pathogenesis of preeclampsia is ...
Background: Community-acquired pneumonia (CAP) is an acute infectious inflammatory disease more often of bacterial etiology that occurs in outside hospital settings. This pathology is an important medical and ...
Background: Today, quite a lot of people suffer from allergic conjunctivitis, despite the sufficient market of monocomponent medicines, there is a shortage of combined medicines based on modern substances ...
Background: Common sorrel (Rumex acetosa L.), a plant from the buckwheat family, is promising for introduction into medicine. Phytochemical studies of common sorrel herba showed that the raw material ...
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