Keyword "GENE" found in the following publications:
MECHANISM OF NEUROPROTECTIVE EFFECT OF MGLUR4 AGONISTS
Introduction: This review of literature is to demonstrate a role of group III metabotropic glutamate receptors in maintaining the level ...
Introduction: PolG-alpha is a nuclear-encoded enzyme which provides replication and repair of mitochondrial DNA. D257A mutation of PolG-alpha leads ...
OVARIAN CANCER: THE SIGNIFICANT OF GENE METHYLATION IN CARCINOGENESIS (REVIEW)
 Background: Epigenetic regulation of genes plays an important role in the development of ovarian cancer. One of ...
MENDELIAN RANDOMIZATION: USING GENETIC INFORMATION IN EPIDEMIOLOGICAL STUDIES (REVIEW)
Background: Mendelian randomization is a research method that exploits the instrumental variable framework using genetic information to assess the ...
The work is devoted to the consideration of two phenomena – the cycle of solar activity (SA), equal to 11 years and ...
MOLECULAR CYTOGENETIC AND CYTOPOSTGENOMIC ANALYSIS OF THE HUMAN GENOME
 Background: Despite the achievements of human genomics, comprehensive genome analysis, including acquiring the knowledge about intercellular and interindividual variations ...
ETHNOGENESIS OF THE UZBEK PEOPLE IN ETHNOGRAPHIC STUDIES OF UZBEKISTAN IN THE YEARS OF INDEPENDENCE
After the establishment of their independent state, almost all the peoples of the world, freed from colonial rule, strive to ...
PSYCHODIAGNOSTIC METHODS AND A TYPOLOGY OF REPRESENTATIVE PERCEPTION SYSTEMS IN STUDENTS
Introduction. The problem of increasing the effectiveness of learning in universities remains relevant. The quality of learning can ...
This paper is dedicated to the development of a concept and software solution for generating human movements based on ...
This article is devoted to the philosophical analysis of the theoretical and methodological foundations of evolutionary and ecological thinking. The ...
ANTI-UTOPIAS AS “SELF-FULFILLING PROPHECIES” ABOUT THE USE OF AI IN INFORMATION WARFARE
The article defines and demonstrates the predictive potential of literary anti-utopias as “self-fulfilling prophecies” describing certain aspects of artificial intelligence ...
Significance. The article compares the existing technologies for solid waste treatment. The analysis is based on the published same-name ...
Background: Atherosclerosis obliterans (AO) and diabetic angiopathy (DA) are known to be peripheral artery diseases (PAD) of multifactorial origin, ...
Background: Disturbances in the differentiation of cells and the processes of cellular renewal of the buccal epithelium, which occur ...
Background: The most common complications of pregnancy associated with metabolic and hemodynamic disorders in the mother-placenta-fetus system are ...
COMPARISON OF EFFICIENCY OF DIFFERENT METHODS OF TRAINING NEURAL NETWORKS
The paper considers several approaches to training multilayer fully connected neural networks. In particular, the authors have developed ...
The article presents the results of research work on the formation of funds of a personal-generic topographic model of the ...
CLINICAL EFFICIENCY OF AZILEKT IN THE THERAPY OF PRIMARY PROGRESSING MULTIPLE SCLEROSIS
Multiple sclerosis − the chronic multifactorial progressing autoimmune disease of the central nervous system developing at any age, but mainly ...
LIFELONG LEARNING FOR ADULTS AND THEORY OF GENERATIONS
The practical implementation of the concept of the «lifelong learning» for adults for their job in the future is considered ...ESTROGENS AND UTERINE FIBROIDS: AN INTEGRATED VIEW
 Background: Uterine fibroids or uterine leiomyomata (UL) are common benign tumors of the uterine myometrium affecting a significant ...
Background: Coronary heart disease (CHD) is the leading pathology among all cardiovascular diseases. Elderly patients with concomitant diseases represent ...
THE EFFECTIVENESS OF THE SYSTEM OF INDICATORS AT THE GENERATING ENTERPRISES OF THE ENERGY COMPLEX
The article discusses the basic concepts of the research problem, where one of the main directions of implementation is ...
PHYTOHORMONAL REGULATION OF IN VITRO FORMATION OF WHEAT ANDROGENIC STRUCTURES
The phenomenon of androgenesis in vitro is widely used in biotechnological investigations of spring wheat. When solving the specific biotechnological ...Background: Chromosome 18p deletion syndrome (18p-) is associated with a loss of chromosomal material of the short arm (partial ...
Background: Phosphatidylethanolamine N-methyltransferase (PEMT) is the enzyme of lipid metabolism that catalyzes the conversion of phosphatidylethanolamine to phosphatidylcholine ...
Background: Hyperandrogenism is the basic indicator of polycystic ovarian syndrome (PCOS) and a key factor in its pathological ...
The article examines religious socialization in the families of Russian Orthodox Church parishioners. The analysis is based on the ...
MORPHOGENIC MICROSPORE AS AN INITIAL CELL OF ANDROGENESIS IN VITRO: REVIEW OF THE PROBLEM
The phenomenon of androgenesis in vitro is widely used in biotechnological investigations of commercially valuable plants. When solving the specific ...The article explores the capabilities of various models of recurrent neural networks in text data generation. ...
NOS3 GENE POLYMORPHISM VARIANTS AND MAIN CHARACTERISTICS OF HEART RATE VARIABILITY IN NORTHERNERS
Background: Heart rate variability as a demonstration of autonomic nervous system function reflects human health and well-being. By ...
GENETIC INTERRELATIONS OF RUSSIAN AND UKRAINIAN POPULATIONS OF BELGOROD REGION
This article presents the results of the study of genetic relationship between the indigenous Russian and Ukrainian population of Belgorod ...
This article discusses the prospects, technologies and methods of using biometric data in cryptosystems. A method of using ...
The article presents the results of the analysis of the problem of “assembly” of the future Russian intellectuals ...
THE PROBLEM OF INCREASING COMPETITIVENESS OF CONSTRUCTION COMPANIES PRODUCTS
The issues of increasing competitiveness of construction companies products were considered on the example of a building complex, namely the ...
The article analyzes the prevalence of radical and extremist beliefs and attitudes in the field of interfaith relations among ...
Background: Mitochondria play a major role in providing cells with energy, but at the same time they are a ...
Background: It is well known that gene polymorphisms of antioxidant defense enzymes contribute to the ischemic stroke (IS) predisposition and ...
ON COURT INTERPRETING IN SWEDEN
The article examines court interpreting in Sweden and analyses one of the main factors that determines court ...
Mesenchymal stem (stromal) cells (MSCs) are self-renewing, cultured adult stem cells which secrete a complex set of multiple soluble biologically ...
The article discusses the construction of a simulation model of the abstract process of converting raw materials into ...
Background: In the genetic and epidemiological study of multifactorial signs (diseases), an important task is to assess the genetic ...
Background: Chronic arterial hypertension and preeclampsia are multifactorial pathologies, in the development of which many groups of genes are ...
Background: Fetal growth retardation (FGR) is one of the most common pregnancy complications that can adversely affect the short- ...
THE STATE OF THE TOURIST B2C MARKET IN RUSSIA
The influence of the market economy on the tourism industry in Russia is great and it is impossible ...
THE CONCEPT OF TECHNOSPHERE: ANALYTICAL REVIEW OF THE FORMATION AND STUDY
The article describes the main theoretical aspects of the study of the technosphere. The authors analyze the definitions and concepts ...
SOCIO-CULTURAL DINAMICS OF RISKS THROUGH «ARROW OF TIME»: THE NEED FOR HUMANISTIC TURN
The article analyzes the postulate of «arrow of time» founded by the Nobel Prize winner I.R. Prigozhin, according to which ...AN ALGORITHM OF SELECTING ECONOMIC OPTIMALITY CRITERIA IN CHEMICAL PRODUCTION
The article provides a comparative analysis of the criteria of optimality of many tonnage chemical-technological systems (CTS). In this ...
Relevance. Glutamate-cysteine ligase (GCL) is the first enzyme of the glutathione cycle, intra- and extracellular antioxidant, whose impaired metabolism ...
Background: To date, bacterial infections caused by microorganisms characterized by antibiotic resistance are one of the leading causes of the ...
MODERN RESEARCH AND THINKING ABOUT THE EPIDEMIOLOGY AND PATHOGENESIS OF UROLITHIASIS
Urolithiasis ranks second in the urologic incidence, being preceded only by infectious and inflammatory diseases of the urinary system. In ...
Background: Coronary heart disease (CHD) is a common disease with a high mortality rate in Russia, so the ...
Introduction. The influence of blended learning on the process of profiling secondary general education is an urgent pedagogical task. ...
Background: Hemorrhagic fever with renal syndrome (HFRS), caused by orthohantaviruses, occupies one of the leading places among natural focal human ...
Background: The pathological process associated with the pathogenic aggregation of tau is called taupathy. The same term is often ...
Background: The use of immune checkpoint inhibitors (ICIs) is a promising therapy in cancer treatment, in particular renal cell ...
The authors carried out a detailed study of the influence of the plasmatic levels of apelin-13 on the development of ...
FAMILY PORTRAIT: EXISTENTIAL OUTLINES AND THE CULTURAL MEANINGS
In modern Russia, which is in the situation of self-determination and strategic guidelines choice, the problem of historical memory has ...ASSOCIATION OF VEGFA, FACTOR V AND PROTHROMBIN GENE POLYMORPHISMS WITH EARLY PREGNANCY LOSS
Background: Many studies conducted to assess the associations between the gene polymorphisms of factor V, prothrombin, and vascular endothelial ...
EVALUATION OF GENETIC DIVERSITY OF VIETNAMESE DOGS BASED ON MITOCHONDRIAL DNA HYPERVARIABLE-1 REGION
Haplogroup E were detected with high frequency in the population of Phu Quoc ridgeback dogs suggesting that this Vietnamese valuable ...CONSIDERING SOME BEHAVIORAL ECONOMIC ISSUES CONCERNING THE DILEMMA OF CUSTOMERS BUYING SMARTPHONES
Different brands are represented on the smartphone market. In this article, the author refers to the study of the dilemma, ...Introduction: The irrational use of medicines leads to a decrease in the quality of care, an increase in treatment costs ...
FUNCTIONAL POTENTIAL OF DEVERBATIVES IN THE ASPECT OF TAXIS RELATIONSHIP ACTUALIZATION
This article deals with the functional potential of deverbative nouns in German.
The article analyzes the aspectual-taxis potential ...
Background: Breast cancer (BC) is a malignant breast tumor, which occupies a leading place both in the structure of ...
Introduction. Since the introduction of profile education in the schools of the Russian Federation, scientific works studying the impact ...
Background: When studying associations of candidate genes with multifactorial diseases, the formation of samples for research is important. One ...
CLINICAL AND GENETIC CHARACTERISTICS OF CYSTIC FIBROSIS IN THE REPUBLIC OF BASHKORTOSTAN
Background: According to estimates of the World Health Organization, 40-50 thousand children worldwide are born each year with ...
- A difficult fundamental problem of developmental biology remains morphogenesis – a continuous chain of changes of shape in ontogeny, resulting ...
The problem of building a picture of the world is closely related to the formation of a person's own image ...
Background: Chronic rhinosinusitis (CRS) is a common disease of the nose and paranasal sinuses with a protracted, relapsing ...
THE USE OF GENERATIVE-ADVERSARIAL NEURAL NETWORKS FOR IMAGE GENERATION
This article discusses the topic of image generation using neural networks. Thanks to the development of deeper learning ...
THE THEORY OF GENERATIONS IN THE CONTEXT OF SOCIOLOGY OF MANAGEMENT
Today, many organizations face the problem of differences in the attitude of employees of different generations to work, ...
MIGRAINE PHARMACOLOGY AND BRAIN ISCHEMIA
 Introduction: The aim of this review article was to analyze in details the mechanism of drugs’ effects in the ...
THE ETHOS OF SCIENCE: HUMANITARIAN EXPERTISE OF INNOVATIVE TECHNOLOGIES IN BIOLOGY AND MEDICINE
The article discusses the ethical problems caused by the development of biomedical technologies. Emphasis is placed on techniques aimed at ...
General aspects of glaucoma: Glaucoma is a heterogeneous multi-factorial disease that is one of the main causes of blindness, along ...
«SMALL NATION IS A STRANGE PHENOMENON…»
The article examines the metaphysical roots of the Serbian tradition. «Small nation» seems to be a strange phenomenon. To explain ...GROWING UP IN THE SHADOW OF THE HOLY SHROUD. MUSLIMS’ SECOND GENERATIONS IN ITALY
Muslims in Italy include not only members of the first generation, but also an increasing number of members of ...
GENERATIONAL CHARACTERISTICS OF PARTICIPATION IN SOCIAL AND POLITICAL PROCESSES
The pertinence of the study of ideas about the peculiarities of participation in socio-political processes of representatives of different ...
THE ROLE OF DNA METHYLATION IN LUNG CANCER (REVIEW)
Background: Lung cancer has been a difficult-to-treat disease for decades, despite the efforts of oncologists and pharmaceutical companies. One ...
FOLK SONGS GENESIS: HISTORICAL AND CULTURAL CONTEXT
The article presents the studies of Russian folk songs evolution in Belgorod Region with reference to culture and history. A ...Introduction: The relationship of numerous metabolic shifts, disorders of hepatocytes functional activity resulting from hypoxia and toxic liver damage ...
CONTRIBUTION OF RS11927381 POLYMORPHISM OF THE IGF2BP2 GENE TO THE PATHOGENESIS OF TYPE 2 DIABETES
Background: Pancreatic beta-cell dysfunction, along with the insulin resistance of peripheral tissues, is a key element in the ...
THE BEGINNINGS OF HUMANITARIAN MATHEMATICS: NUMBER PRENATOLOGY
The main problem of the article is to consider the humanitarian foundations of mathematics, which make it possible to develop ...
STUDY OF PHARMACOLOGICAL ACTIVITY OF NIGELLA DAMASCENA FIXED OIL IN EXPERIMENT
Introduction: Literature data, rich chemical macro-microelement composition set the stage for experimental pharmacological study of adaptogene and lipid protective ...
Background: The widespread use of pesticides can lead to a violation of the ecological balance between the ...
One of the most important problems that exist in Russian historical science and philosophy, starting with the grandiose, but extremely ...
Background: Cystic fibrosis (CF) is an autosomal recessive disease that occurs with a frequency of 1:1,500 to ...
IMPLEMENTATION OF CASE TECHNOLOGY WHEN TEACHING GEOMETRY BY MEANS OF ONLINE SERVICES
 The events of 2020 related to the coronavirus pandemic and the introduction of distance learning have actualized the problem ...
Background: Glycogen synthase 2 (GYS2) catalyzes a key step in glycogenesis in the liver. Loss-of-function mutations in the GYS2 ...
Background: Eczema is a common chronic disease characterized by inflammation of the skin. The aim of the study: ...
MODERN GENOMICS IN STUDYING THE PROBLEMS OF HUMAN ADAPTATION TO CLIMATE IN NORTH SIBERIA
Background: Indigenous people of north Siberia live in some of the harshest natural conditions on Earth, experiencing prolonged ...
Background: The superoxide dismutase 2 (SOD2) gene encodes a mitochondrial enzyme whose main function is to convert superoxide ...
Background: Host-pathogenic interaction is a necessary but not sufficient precondition for the development of the disease. The immune response ...
FOLK CULTURE IN THE ASSESSMENTS OF RUSSIAN STUDENT YOUTH
 Information technologies have changed all spheres of human life. This fact has given particular importance to the context of ...
Background: In the elderly, age-related macular degeneration has a high prevalence and often causes a decrease and complete ...
Background: Gentamicin induces testicular damage in association with oxidative stress explained by different mechanisms, including gene expression ...
This article or essay deals with the specific features of Konstantin Leontiev’s critical study devoted to a comparative investigation of ...
Background: Interphase chromosome-specific multicolor banding (ICS-MCB) has been developed for studying whole chromosomes in interphase nuclei at any stage ...
SOCIOCULTURAL PRACTICE AS A TOOL FOR RAISING THE CULTURAL LEVEL OF STUDENTS
Introduction. The culture of the teacher, including the professional pedagogical culture and other characteristics of the personality, is the ...
MOLECULAR-GENETIC DETERMINANTS OF INFERTILITY IN GENITAL ENDOMETRYOSIS
Background: Genital endometriosis is an urgent problem of modern medicine. It is one of the hard-to-explain diseases and is ...
POLYMORPHISM OF IL10, CTLA4 GENES AND PREDISPOSITION TO RHEUMATOID ARTHRITIS
Background. Rheumatoid arthritis (RA) is a systemic autoimmune disease, accompanied by chronic inflammation of the joints synovial membrane and ...
ZNF804A RS1344706 GENE POLYMORPHISM AND CLINICAL HETEROGENEITY OF SCHIZOPHRENIA
 Background: Replication of genome-wide association study (GWAS) loci for schizophrenia in different populations as well as the study ...
WRITTEN VS GENERATED TEXT: “NATURALNESS” AS A TEXTUAL AND PSYCHOLINGUISTIC CATEGORY
In the context of the development of text generation technologies, the opposition “naturalness − unnaturalness of text” has been ...
REVISTING THE FIRST SCIENTIFIC AND WORLDVIEW EXPERIENCE OF N. N. STRAKHOV
The study is aimed at clarifying the theoretical and methodological originality of the organic approach, as it first appeared in ...Background: Polymorphisms and disruption of the expression profile of miRNA genes are associated with systemic diseases (autoimmune and cardiovascular diseases). ...
A GRAPH-BASED APPROACH TO CLOSED-DOMAIN NATURAL LANGUAGE GENERATION
Graph-based Natural Language Processing (NLP) methods have seen significant advancements in recent years with the development of Large Language ...
GENERALIZED REPRESENTATIONS OF SIBERIA IN ELECTRONIC SCIENTIFIC COMMUNICATIONS
 This paper describes how we identified the images of a region and the regions’ generalized representations based on these multiple ...
Background: Peptic ulcer disease (PUD) is a chronic recurrent disease that occurs with alternating periods of exacerbation and remission, ...
2Q14 DE NOVO INTERSTITIAL DELETION IN A GIRL WITH INTELLECTUAL DISABILITIES AND MALFORMATIONS
Background: Neurodevelopmental disorders have a prevalence of approximately 3% in the population, the genetic factor is involved in ...
STRUCTURE PLAN OF LIVING ORGANISMS. BACKGROUND
The article examines one of the most interesting problems of theoretical biology, the origins of which are already found in ...
Background: Today, percutaneous coronary intervention (PCI) is the most effective treatment of coronary artery disease (CAD). Despite all technical ...
Background: Positioned as one of the central members in cellular antioxidant defense, glutathione reductase (GSR) determines the oxidative status ...
Background: Preeclampsia (PE) is one of the most serious pregnancy complications and is the leading cause of maternal and ...
THE TECHNIQUE OF FORMATION AND CORRECTION OF HIGH RESOLUTION SPACE IMAGES
The paper presents a generalized formalized bipartite graph of a cruising technology of high resolution space image formation and examines ...
Background: Bacterial vaginosis (BV) is a common vaginal infection that causes significant gynecological and obstetric morbidity. Despite ...
RS34845949 POLYMORPHISM OF THE SASH1 GENE IS ASSOCIATED WITH THE RISK OF PREECLAMPSIA
 Background: Preeclampsia (PE) is a multisystem pathological condition that occurs in the second half of pregnancy (after the ...
The leading focus of the Smart City project in Russia is human orientation. The question is raised, which part of ...
Introduction: In modern medicine new pharmacotherapeutic systems significantly reducing the risk of complications are being actively searched for. The study ...
RAPID VARIATIONS IN THE OPERATIONS OF PROBLEM-ORIENTED COMPUTER ARITHMETIC
The authors provide a quick way of building modifications, operations and algorithms of mass data processing with deconvolution of satellite ...
Structure and synthesis of Erythropoietin: Erythropoietin (EPO) is a glycoprotein hormone.
Recombinant Erythropoietin (Epoetin): Human recombinant erythropoietin is characterised as ...
WOUND HEALING EFFECT OF ORGANOMETALLIC ZINC COMPLEX IN THE RAT MODEL OF PLANAR SKIN WOUND
 Background: The complex and dynamic process of wound healing involves the stages of inflammation, proliferation and maturation of the ...
PRINCIPLES OF PHARMACOLOGICAL CORRECTION OF PULMONARY ARTERIAL HYPERTENSION
Definition and classification: Pulmonary hypertension (PH) is a group of life-threatening progressive diseases of various genesis, characterized by a ...
Background: When conducting population-genetic and genetic-epidemiological studies, the endogamy index should be taken into account to assess ...
Introduction: At the present time many clinical and experimental studies are devoted to the correction of hepatocytes and liver ...
Introduction: Tau protein is classically involved in the pathogenesis of a neurodegenerative processes, such as Parkinson’s disease. This study was ...
Background: According to statistics, the first place among the causes of death worldwide is occupied by cardiovascular diseases ...
ASSESSMENT OF DRUG UTILIZATION PATTERN OF STEROIDS IN A DISTRICT GENERAL HOSPITAL IN AMRAVATI REGION
Introduction: Rational use of corticosteroids is very important in the long term for improving patient safety. The main objective of ...
- The study assessed changes in hemodynamic and biochemical parameters, vascular age and 5-year cardiovascular risk on the background of complex ...
HUMANITARIAN EXPERTISE AND PROSPECTIVE GENOMIC RESEARCH
 The article analyzes the influence of the so-called "humanitarian" expertise on research conducted in the field of biology of individual ...
Background: The ideal dose of drugs varies widely among patients, mainly due to genetic factors. Introduction to clinical practice ...
Background: The study of the multifactor nature of anxiety is caused by its role in multiple aspects of human ...
The article discusses the dynamics of various indicators of social capital in Russia and the relationship of social capital ...
Background: Kallmann syndrome (KS) and CHARGE syndrome (CS) are rare heritable disorders in which anosmia and hypogonadotropic hypogonadism ...
INDIVIDUAL RESILIENCE IN THE STUDY OF LONGEVITY FACTORS
Background: In recent years, the issues of longevity and its determining factors have been actively discussed. Among studies ...
Background: The dysfunction of vascular endothelial growth factor A (VEGFA) is one of the leading factors of macro- and ...
OPEN-TYPE TASKS AS A MEANS OF DEVELOPING “SOFT SKILLS” IN MATH LESSONS
The modern multidimensionally transforming world poses the challenges of a new reality, while the presence of a certain cultural ...
FEATURES OF FORMATION THINKING IN THE DIGITAL ENVIRONMENT (COMPARATIVE ANALYSIS OF GENERATIONS)
In the 21st century, it is impossible to imagine human life without the use of digital technologies. Digital technologies ...
Background: Non-developing pregnancy is one of the most difficult medical and social problems of modern obstetrics and gynecology, which ...
Background: The continuing change in the demographic structure of society in different states is accompanied by a restless increase ...
THE CHOICE OF ANTIMICROBIAL THERAPY AMONG PHYSICIANS IN THE TREATMENT OF GESTATIONAL PYELONEPHRITIS
From 1 to 10% of the physiological pregnancy complicated by acute pyelonephritis. The purpose work- analyze the choice of antimicrobial ...
Background: It is known that the development of coronary heart disease (CHD) as a polygenic multifactorial pathology is ...
MOLECULAR AND GENETIC CHARACTERISTICS OF PATIENTS WITH HYPERPLASIA AND ENDOMETRIC POLYPS
Background. Hyperplastic processes of the endometrium (GGE) are among the most frequent gynecological diseases, leading to a loss of ...
This paper is devoted to the study of generative modeling in design used: this is an iterative process ...
GENETIC MARKERS OF KNEE OSTEOARTHRITIS IN WOMEN OF THE CENTRAL CHERNOZEM REGION OF RUSSIA
Background: Knee osteoarthritis (KO) is a multifactorial disease. Among the many risk factors for the disease, the role of ...
Background: Gastric cancer (GC) is one of the most serious diseases, occupying a leading position among the causes of ...
Background: The level of IL-1β in blood plasma is determined not only by pro-inflammatory stimuli, but also by ...
SIGNAL MOLECULES INVOLVED IN THE FORMATION OF NEW NERVE ENDINGS IN ENDOMETRIOSIS (REVIEW)
Background: The mechanism of the development of pain syndrome in endometriosis is heterogeneous. The study has been established that ...
RETROELEMENTS IN TARGETED ANTITUMOR THERAPY (REVIEW)
Background: Pathological expression of retroelements is determined in most malignant tumors, which reflects the pathogenesis of tumors, since activated ...
Background: The priority problem of modern gerontology and geriatrics is currently social isolation, which represents an objective ...
